公开(公告)号：BR8905441A

公开(公告)日：1990-10-23

申请号：BR8905441

申请日：1989-10-25

Applicant: TIDWELL RICHARD R ,  DIETER GERATZ J ,  HALL JAMES E ,  KYLE DENNIS E ,  MAX GROGL ,  KWASI A CHEMENG

Inventor： TIDWELL RICHARD R ,  GERATZ J DIETER ,  HALL JAMES EDWIN ,  KYLE DENNIS E ,  GROGL MAX ,  CHEMENG KWASI A

IPC: A61K31/155 ,  A61K31/41 ,  A61P11/00 ,  A61P33/02 ,  A61P33/10 ,  A61P43/00 ,  C07C257/18 ,  C07C323/60 ,  C07D233/20 ,  C07D239/22 ,  C07D239/24 ,  C07C103/26 ,  C07C103/28

Abstract: New pentamidine analogue compounds and compositions containing the new analogues are disclosed. Methods for the treatment of, and prophylaxis against, Pneumocystis carinii pneumonia, and methods for treating leishmaniasis, giardiasis, and malaria using the new analogues are also disclosed.

公开(公告)号：CA2102035C

公开(公告)日：2006-12-19

申请号：CA2102035

申请日：1993-10-29

Applicant: LAWSON DAVID F ,  HALL JAMES E ,  OZAWA YOICHI

Inventor： LAWSON DAVID F ,  HALL JAMES E ,  OZAWA YOICHI

IPC: C08F4/48 ,  C07D295/22 ,  C08C19/44 ,  C08F4/00 ,  C08F4/06 ,  C08F4/08 ,  C08F4/30 ,  C08F36/04 ,  C08F236/04 ,  C08L21/00

Abstract: An acyclic alkane soluble anionic polymerization initiator includes a mixtur e of from about 90 to about 10 parts by weight of a lithio amine having the gener al formula A1Li and from about 10 to about 90 parts by weight of at least one other lithio amine having the general formula A2Li. A1 and A2 are selected from the dialkyl, alkyl, cycloalkyl and dicycloalkyl amine radicals and cyclic amine radicals. There is also provided a method of forming a mixture of anionic polymerization initiators, a functionalized polymer and a method of forming a functionalized polymer.

公开(公告)号：CA2102035A1

公开(公告)日：1994-05-01

申请号：CA2102035

申请日：1993-10-29

Applicant: LAWSON DAVID F ,  HALL JAMES E ,  OZAWA YOICHI

Inventor： LAWSON DAVID F ,  HALL JAMES E ,  OZAWA YOICHI

IPC: C08F4/48 ,  C07D295/22 ,  C08C19/44 ,  C08F4/00 ,  C08F4/06 ,  C08F4/08 ,  C08F36/04 ,  C08F236/04 ,  C08L21/00 ,  C08F4/30

Abstract: An acyclic alkane soluble anionic polymerization initiator includes a mixture offrom about 90 to about 10 parts by weight of a lithio amine having the general formula A1Li and from about 10 to about 90 parts by weight of at least one other lithio amine having the general formula A2Li. A1 and A2 are selected from the dialkyl, alkyl,cycloalkyl and dicycloalkyl amine radicals and cyclic amine radicals. There is also provided a method of forming a mixture of anionic polymerization initiators, a functionalized polymer and a method of forming a functionalized polymer.

公开(公告)号：CA2001359A1

公开(公告)日：1990-04-25

申请号：CA2001359

申请日：1989-10-24

Applicant: TIDWELL RICHARD R ,  GERATZ J DIETER ,  HALL JAMES E ,  KYLE DENNIS E ,  GROGL MAX ,  OHEMENG KWASI A

Inventor： TIDWELL RICHARD R ,  GERATZ J DIETER ,  HALL JAMES E ,  KYLE DENNIS E ,  GROGL MAX ,  OHEMENG KWASI A

IPC: A61K31/155 ,  A61K31/41 ,  A61P11/00 ,  A61P33/02 ,  A61P33/10 ,  A61P43/00 ,  C07C257/18 ,  C07C323/60 ,  C07D233/20 ,  C07D239/22 ,  C07D239/24

Abstract: New pentamidine analogue compounds and compositions containing the new analogues are disclosed. Methods for the treatment of, and prophylaxis against, Pneumocystis carinii pneumonia, and methods for treating leishmaniasis, giardiasis, and malaria using the new analogues are also disclosed.

公开(公告)号：WO2008085428A3

公开(公告)日：2008-11-13

申请号：PCT/US2007026221

申请日：2007-12-21

Applicant: FIRESTONE POLYMERS LLC ,  DEDECKER MARK N ,  HALL JAMES E ,  GRAVES DANIEL F

Inventor： DEDECKER MARK N ,  HALL JAMES E ,  GRAVES DANIEL F

IPC: C08F287/00 ,  C08L51/00 ,  C08L55/02

CPC classification number: C08F287/00

Abstract: A process for preparing a rubber comprising polymeric composition, and the resulting compositions, and certain isoprene comprising interpolymers.

Abstract translation: 制备橡胶的方法，所述橡胶包含聚合物组合物和所得组合物，以及包含共聚体的某些异戊二烯。

公开(公告)号：WO2008014464A2

公开(公告)日：2008-01-31

申请号：PCT/US2007/074611

申请日：2007-07-27

Applicant: BRIDGESTONE CORPORATION ,  WANG, Xiaorong ,  BOHM, Georg, G.A. ,  WARREN, Sandra ,  PAN, Xiao-Dong ,  HALL, James, E.

Inventor： WANG, Xiaorong ,  BOHM, Georg, G.A. ,  WARREN, Sandra ,  PAN, Xiao-Dong ,  HALL, James, E.

IPC: B32B27/14

CPC classification number: C08L51/006 ,  B82Y30/00 ,  C08F257/02 ,  C08F285/00 ,  C08K2201/011 ,  C08L21/00 ,  C08L51/003 ,  C08L53/005 ,  C08L53/02 ,  C08L2666/24 ,  C08L2666/02

Abstract: A polymeric nanoparticle composition is provided. The nanoparticle may be of a core/shell configuration with an interphase region connecting the core and the shell. The mean average diameter of the polymer nanoparticles may be less than about 250 nm. The size, composition, and/or configuration of the interphase region may be varied to achieve desired physical and/or chemical properties of the resulting polymeric nanoparticles, and of the compositions into which the nanoparticles are compounded.

Abstract translation: 提供聚合物纳米颗粒组合物。 纳米颗粒可以是具有连接芯和壳的相间区域的核/壳构型。 聚合物纳米颗粒的平均直径可以小于约250nm。 相间区域的尺寸，组成和/或构型可以改变以实现所得聚合物纳米颗粒以及纳米颗粒复合到其中的组合物的期望的物理和/或化学性质。

公开(公告)号：WO2004058874A1

公开(公告)日：2004-07-15

申请号：PCT/US2003/040375

申请日：2003-12-18

Applicant: BRIDGESTONE CORPORATION ,  WANG, Xiaorong ,  FUDEMOTO, Hiroyuki ,  HALL, James, E. ,  ARAKI, Shunji ,  HOGAN, Terrence, E. ,  FOLTZ, Victor ,  SADHUKHAN, Pat ,  BOHM, Georg, G., A.

Inventor： WANG, Xiaorong ,  FUDEMOTO, Hiroyuki ,  HALL, James, E. ,  ARAKI, Shunji ,  HOGAN, Terrence, E. ,  FOLTZ, Victor ,  SADHUKHAN, Pat ,  BOHM, Georg, G., A.

IPC: C08K9/04

CPC classification number: C08F8/44 ,  C01B33/44 ,  C01P2002/88 ,  C01P2004/54 ,  C01P2004/61 ,  C07C17/16 ,  C08F8/32 ,  C08F210/10 ,  C08K7/04 ,  C08K9/04 ,  C08L23/22 ,  C08L23/283 ,  C08L2205/02 ,  C09C1/42 ,  C07C22/04 ,  C08F10/10 ,  C08F4/16 ,  C08F2/44 ,  C08L2666/06 ,  C08F222/06

Abstract: A polymer composition of low gas permeability. The composition includes an exfoliated organically-modified clay, butyl rubber, and a polymeric exfoliant. A method for producing the butyl composition by dry mixing the butyl rubber with the exfoliated clay is also provided.

Abstract translation: 低透气性的聚合物组合物。 组合物包括剥离的有机改性粘土，丁基橡胶和聚合物去角质。 还提供了通过将丁基橡胶与剥离粘土干混合来制备丁基组合物的方法。

公开(公告)号：WO2003085040A3

公开(公告)日：2003-10-16

申请号：PCT/US2002/031817

申请日：2002-10-04

Applicant: BRIDGESTONE CORPORATION ,  WANG, Xiaorong ,  LIN, Chenchy, Jeffrey ,  HALL, James, E. ,  WARREN, Sandra ,  KROM, James, A. ,  KONDO, Hajime ,  MORITA, Koichi

Inventor： WANG, Xiaorong ,  LIN, Chenchy, Jeffrey ,  HALL, James, E. ,  WARREN, Sandra ,  KROM, James, A. ,  KONDO, Hajime ,  MORITA, Koichi

IPC: C08F8/00

Abstract: A nano-particle composition including a poly (alkenylbenzene) core and a poly (conjugated diene) or a poly(alkylene) surface layer is provided. The nano-particles have a mean average diameter less than about 100nm. The nano-particles can be modified via, for example, hydrogenation or functionalization. The nano-particles can advantageously be incorporated into rubbers, elastomers, and thermoplastics.

公开(公告)号：WO1996040117A1

公开(公告)日：1996-12-19

申请号：PCT/US1996008972

申请日：1996-06-03

Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ,  GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  DUKE UNIVERSITY ,  AUBURN UNIVERSITY ,  TIDWELL, Richard, R. ,  HALL, James, E. ,  BOYKIN, David, W. ,  DYKSTRA, Christine, C. ,  PERFECT, John, R. ,  BLAGBURN, Byron, L.

Inventor： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ,  GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  DUKE UNIVERSITY ,  AUBURN UNIVERSITY

IPC: A61K31/40

CPC classification number: C07D403/04 ,  A61K31/403 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/506 ,  C07D209/86 ,  C07D209/88 ,  C07D403/14 ,  Y02A50/488

Abstract: The present invention provides methods for treating Cryptococcus neoformans, Cryptosporidium parvum, and Candida albicans in a subject in need of such treatment. The methods comprise administering to the subject a compound of Formula (I), wherein X is located in the para or meta positions and is loweralkyl, loweralkoxy, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, alkylaryl, halogen, or (a), wherein each R2 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl or two R2 groups together represent C2-C10 alkylene, or two R2 groups together represent (b), wherein m is from 1-3 and R4 is H, (c) or -CONHR5NR6R7, wherein R5 is loweralkyl, R6 and R7 are each independently selected from the group consisting of H and lower alkyl; each R8 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl, or two R8 groups together represent C2-C10 alkylene; R9 is H, hydroxy, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl; R3 is H, hydroxy, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl; R1 is H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, alkylaryl, or halogen; or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明提供了在需要这种治疗的受试者中治疗隐球菌新隐球蛋白，小隐孢子虫和白色念珠菌的方法。 所述方法包括向受试者施用式（I）化合物，其中X位于对位或间位，且为低级烷基，低级烷氧基，烷氧基烷基，羟烷基，氨基烷基，烷基氨基烷基，环烷基，芳基，烷基芳基，卤素或（ ），其中每个R 2独立地选自H，低级烷基，烷氧基烷基，羟基烷基，氨基烷基，烷基氨基烷基，环烷基，芳基或烷基芳基或两个R 2基团一起表示C 2 -C 10亚烷基，或两个R 2基团一起表示（b ），其中m为1-3，R4为H，（c）或-CONHR5NR6R7，其中R5为低级烷基，R6和R7各自独立地选自H和低级烷基; 每个R 8独立地选自H，低级烷基，烷氧基烷基，羟基烷基，氨基烷基，烷基氨基烷基，环烷基，芳基或烷基芳基，或两个R 8基团一起表示C 2 -C 10亚烷基; R9是H，羟基，低级烷基，烷氧基烷基，羟基烷基，氨基烷基，烷基氨基烷基，环烷基，芳基或烷基芳基; R3是H，羟基，低级烷基，烷氧基烷基，羟基烷基，氨基烷基，烷基氨基烷基，环烷基，芳基或烷基芳基; R1是H，低级烷基，烷氧基烷基，羟基烷基，氨基烷基，烷基氨基烷基，环烷基，芳基，烷基芳基或卤素; 或其药学上可接受的盐。

公开(公告)号：WO2010045230A2

公开(公告)日：2010-04-22

申请号：PCT/US2009/060500

申请日：2009-10-13

Applicant: BRIDGESTONE CORPORATION ,  QIN, Zengquan ,  POULTON, Jason, T. ,  HALL, James, E. ,  DEDECKER, Mark, N.

Inventor： QIN, Zengquan ,  POULTON, Jason, T. ,  HALL, James, E. ,  DEDECKER, Mark, N.

IPC: C08F216/12 ,  C08F230/08 ,  C08F212/10

CPC classification number: C08C19/44 ,  C08F236/06 ,  C08F297/04 ,  C08F2438/00 ,  C08F230/08 ,  C08F216/1416 ,  C08F212/08

Abstract: Terminally functionalized polymers that are living or pseudo-living polymers reacted with certain allyl glycidyl ethers, or certain allylhalosilanes or combinations thereof, and a process for preparing the terminally functionalized polymers. Rubber- modified polymeric compositions comprising the terminally functionalized polymers.

Abstract translation: 作为活性或假活性聚合物的终端官能化聚合物与某些烯丙基缩水甘油醚或某些烯丙基卤硅烷或其组合反应，以及制备末端官能化聚合物的方法。 包含末端官能化聚合物的橡胶改性聚合物组合物。