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公开(公告)号：DE69428957D1
公开(公告)日：2001-12-13
申请号：DE69428957
申请日：1994-08-26
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET DR KLAUS , CZECH DR JOERG , HOFFMANN DR DIETER , TILLEQUIN PROF FRANCOIS , FLORENT DR JEAN-CLAUDE , AZOULAY DR MICHEL , MONNERET DR CLAUDE , JACQUESY PROF JEAN-CLAUDE , GESSON PROF JEAN-PIERRE , KOCH PROF MICHEL , VASELLA PROF ANDREA , HOOS ROLAND
IPC: C07H15/203 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P35/00 , A61P43/00 , C07H15/244
Abstract: Enzymatically cleavable prodrugs with reduced Michaelis-Menten constant (Km) are described.
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公开(公告)号：ES2148259T3
公开(公告)日：2000-10-16
申请号：ES94114195
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET KLAUS DR , CZECH JORG DR , HOFFMANN DIETER DR , TILLEQUIN FRANCOIS , FLORENT JEAN-CLAUDE , AZOULAY MICHEL
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号：DE69425356T2
公开(公告)日：2002-04-18
申请号：DE69425356
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET KLAUS , CZECH JOERG , HOFFMANN DIETER , TILLEQUIN FRANCOIS , FLORENT JEAN-CLAUDE , AZOULAY MICHEL , MONNERET CLAUDE , JACQUESY JEAN-CLAUDE , GESSON JEAN-PIERRE , KOCH MICHEL
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号：AT194920T
公开(公告)日：2000-08-15
申请号：AT94114195
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET KLAUS , CZECH JOERG , HOFFMANN DIETER , TILLEQUIN FRANCOIS , FLORENT JEAN-CLAUDE , AZOULAY MICHEL , MONNERET CLAUDE , JACQUESY JEAN-CLAUDE , GESSON JEAN-PIERRE , KOCH MICHEL
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号：AT208213T
公开(公告)日：2001-11-15
申请号：AT94113388
申请日：1994-08-26
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET DR KLAUS , CZECH DR JOERG , HOFFMANN DR DIETER , TILLEQUIN PROF FRANCOIS , FLORENT DR JEAN-CLAUDE , AZOULAY DR MICHEL , MONNERET DR CLAUDE , JACQUESY PROF JEAN-CLAUDE , GESSON PROF JEAN-PIERRE , KOCH PROF MICHEL , VASELLA PROF ANDREA , HOOS ROLAND
IPC: C07H15/203 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P35/00 , A61P43/00 , C07H15/244
Abstract: Enzymatically cleavable prodrugs with reduced Michaelis-Menten constant (Km) are described.
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Patent Agency Ranking
公开(公告)号：DE69428957T2
公开(公告)日：2002-06-06
申请号：DE69428957
申请日：1994-08-26
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET DR KLAUS , CZECH DR JOERG , HOFFMANN DR DIETER , TILLEQUIN PROF FRANCOIS , FLORENT DR JEAN-CLAUDE , AZOULAY DR MICHEL , MONNERET DR CLAUDE , JACQUESY PROF JEAN-CLAUDE , GESSON PROF JEAN-PIERRE , KOCH PROF MICHEL , VASELLA PROF ANDREA , HOOS ROLAND
IPC: C07H15/203 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P35/00 , A61P43/00 , C07H15/244
Abstract: Enzymatically cleavable prodrugs with reduced Michaelis-Menten constant (Km) are described.
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公开(公告)号：PT642799E
公开(公告)日：2002-04-29
申请号：PT94113388
申请日：1994-08-26
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： MONNERET CLAUDE , FLORENT JEAN-CLAUDE , GESSON JEAN-PIERRE , JACQUESY JEAN-CLAUDE , KOCH MICHEL , TILLEQUIN FRANCOIS , BOSSLET KLAUS , AZOULAY MICHEL , JORG CZECH DR , VASELLA ANDREA , DIETER HOFFMANN DR , HOOS ROLAND
IPC: C07H15/203 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P35/00 , A61P43/00 , C07H15/244
Abstract: Enzymatically cleavable prodrugs with reduced Michaelis-Menten constant (Km) are described.
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公开(公告)号：PT648503E
公开(公告)日：2000-11-30
申请号：PT94114195
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： HOFFMANN DIETER , MONNERET CLAUDE , FLORENT JEAN-CLAUDE , GESSON JEAN-PIERRE , CZECH JORG , KOCH MICHEL , TILLEQUIN FRANCOIS , ROSSLET KLAUS , AZOULAY MICHEL , JACOOUESY JEAN-CLAUDE
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号：DK0648503T3
公开(公告)日：2000-10-02
申请号：DK94114195
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： CZECH JOERG DR , HOFFMANN DIETER DR , TILLEQUIN FRANCOIS , AZOULAY MICHEL , MONNERET CLAUDE , KOCH MICHEL , BOSSLET KLAUS DR , FLORENT JEAN-CLAUDE , JACQUESY JEAN-CLAUDE , GESSON JEAN-PIERRE
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号：DE69425356D1
公开(公告)日：2000-08-31
申请号：DE69425356
申请日：1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor： BOSSLET KLAUS , CZECH JOERG , HOFFMANN DIETER , TILLEQUIN FRANCOIS , FLORENT JEAN-CLAUDE , AZOULAY MICHEL , MONNERET CLAUDE , JACQUESY JEAN-CLAUDE , GESSON JEAN-PIERRE , KOCH MICHEL
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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