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    TEMPERATURE-REGULATED CULTURE PLATES
    2.
    发明申请
    TEMPERATURE-REGULATED CULTURE PLATES 审中-公开
    温度调节培养板

    公开(公告)号：WO2007092571A3

    公开(公告)日：2007-12-27

    申请号：PCT/US2007003401

    申请日：2007-02-07

    Applicant: WAFERGEN INC ,  JOSEPH VICTOR ,  HUDA AMJAD ,  ROGERS JOSEPH F

    Inventor： JOSEPH VICTOR ,  HUDA AMJAD ,  ROGERS JOSEPH F

    IPC: C12Q1/68 ,  C12N5/00

    CPC classification number: C12M23/48 ,  C12M23/12 ,  C12M23/22 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/44

    Abstract: Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO 2 /O 2 /N 2 levels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.

    Abstract translation: 本文描述的是可用于细胞培养的环境分离的组织培养装置，以及包括这些装置的系统以及使用它们的方法。 这些设备可以包括用于调节设备的一个或多个井内的微环境的控制特征。 例如，板载功能可以调节温度，湿度，pH值，介质水平，介质组成，CO 2 / SUB <2> / N 2 水平，药物浓度，细胞密度，副产物（或产物）生产以及室内物质的混合。 可以在不打开设备的情况下将材料添加到设备的孔中或从设备的孔中取出材料。 本文还描述了用于分析和控制井内的微环境的控制器。 因此，本文所述的平板可以在不需要单独的培养箱的情况下使用，从而允许细胞连续分析（例如成像），允许实时反应，同时在显微镜下监测几小时，几天甚至几周。

    TEMPERATURE-REGULATED CULTURE PLATES
    4.
    发明申请
    TEMPERATURE-REGULATED CULTURE PLATES 审中-公开
    温度调节文化板

    公开(公告)号：WO2007092571A2

    公开(公告)日：2007-08-16

    申请号：PCT/US2007/003401

    申请日：2007-02-07

    Applicant: WAFERGEN, INC. ,  JOSEPH, Victor ,  HUDA, Amjad ,  ROGERS, Joseph, F.

    Inventor： JOSEPH, Victor ,  HUDA, Amjad ,  ROGERS, Joseph, F.

    CPC classification number: C12M23/48 ,  C12M23/12 ,  C12M23/22 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/44

    Abstract: Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO 2 /O 2 /N 2 levels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.

    Abstract translation: 本文描述了可用于细胞培养的环境分离的组织培养装置，以及包括这些装置的系统和使用它们的方法。 这些装置可以包括用于调节装置的井或井内的微环境的控制特征。 例如，车载特征可以调节温度，湿度，pH，介质水平，介质组成，CO 2 / O 2 / N 2 >水平，药物浓度，细胞密度，副产物（或产品）生产以及室内物质的混合。 可以在不打开设备的情况下将材料添加到设备的井中或从设备的井中取出。 本文还描述了用于分析和控制井内微环境的控制器。 因此，可以使用本文所述的板，而不需要单独的培养箱，允许细胞连续分析（例如，成像），允许实时反应，同时在显微镜下监测数小时，数天甚至数周。

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