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公开(公告)号：US20220106382A1
公开(公告)日：2022-04-07
申请号：US17425095
申请日：2020-01-21
Applicant: PAUL SCHERRER INSTITUT , INTERAX BIOTECH AG
Inventor： BENOIT MEGER , MARTIN KONRAD OSTERMAIER , PHILIPP BERGER , MIRJAM ZIMMERMANN , MARIA WALDHOER
IPC: C07K14/72
Abstract: The invention relates to the field of arrestin mutants, especially mutants of beta-arrestin, a complex of the mutant beta-arrestin and a G-protein-coupled receptor (GPCR), and a vector encoding the mutant beta-arrestin.
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公开(公告)号：WO2020152152A1
公开(公告)日：2020-07-30
申请号：PCT/EP2020/051394
申请日：2020-01-21
Applicant: INTERAX BIOTECH AG , PAUL SCHERRER INSTITUT
Inventor： MEGER, Benoit , OSTERMAIER, Martin, Konrad , WALDHOER, Maria , BERGER, Philipp , ZIMMERMANN, Mirjam
Abstract: The present invention relates to the field of arrestin mutants, especially mutants of beta-arrestin, a complex of the mutant beta-arrestin of the invention and a GPCR, and a vector encoding the mutant beta-arrestin of the invention.
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公开(公告)号：WO2022148879A1
公开(公告)日：2022-07-14
申请号：PCT/EP2022/050415
申请日：2022-01-11
Applicant: STICHTING VU , INTERAX BIOTECH AG
Inventor： RIEMENS, Rick , BOSMA, Reggie , ARIMONT SEGURA, Marta , LEURS, Rob , DE ESCH, Iwan , WIJTMANS, Maikel , VISSCHER, Henry , WALDHOER, Maria , RIZK, Aurélien , ZIMMERMANN, Mirjam , ROTH, Susanne , DOBBERSTEIN, Nadine
IPC: C07D401/12 , C07D239/95 , C07D403/12 , C07D405/12 , A61P35/00 , A61K31/517
Abstract: The present disclosure relates to compounds of formula (I) comprising a heteroaryl, such as derivatives of quinazolines, which can act as modulators of ACKR3. The present disclosure also relates to the use of these compounds as a drug.
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Patent Agency Ranking
公开(公告)号：CA3127255A1
公开(公告)日：2020-07-30
申请号：CA3127255
申请日：2020-01-21
Applicant: INTERAX BIOTECH AG , SCHERRER INST PAUL
Inventor： MEGER BENOIT , OSTERMAIER MARTIN KONRAD , WALDHOER MARIA , BERGER PHILIPP , ZIMMERMANN MIRJAM
Abstract: The present invention relates to the field of arrestin mutants, especially mutants of beta-arrestin, a complex of the mutant beta-arrestin of the invention and a GPCR, and a vector encoding the mutant beta-arrestin of the invention.
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公开(公告)号：EP4238970A1
公开(公告)日：2023-09-06
申请号：EP22159896.4
申请日：2022-03-03
Applicant: InterAx Biotech AG , Stichting VU
Inventor： RIEMENS, Rick , BOSMA, Reggie , LEURS, Rob , DE ESCH, Iwan , WIJTMANS, Maikel , VISSCHER, Henry , NIKOLAEV, Yaroslav , KANEV, Georgi , ZIMMERMANN, Mirjam , RIZK, Aurélien , POTENZA, Alessandro , STEPNIEWSKI, Tomasz Maciej
IPC: C07D413/06 , A61P35/00
Abstract: The present disclosure relates to compounds of formula (I) comprising a (4-piperidinylmethyl) carboxamide moiety, which can act as modulators of ACKR3. The present disclosure also relates to the use of these compounds as a drug.
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公开(公告)号：EP4486739A1
公开(公告)日：2025-01-08
申请号：EP23707976.9
申请日：2023-03-03
Applicant: InterAx Biotech AG , Stichting VU
Inventor： RIEMENS, Rick , BOSMA, Reggie , LEURS, Rob , DE ESCH, Iwan , WIJTMANS, Maikel , VISCHER, Henry , NIKOLAEV, Yaroslav , KANEV, Georgi , ZIMMERMANN, Mirjam , RIZK, Aurélien , POTENZA, Alessandro , STEPNIEWSKI, Tomasz Maciej , WIJFFELAARS, Laura
IPC: C07D413/06 , A61P35/00
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公开(公告)号：EP3914916A1
公开(公告)日：2021-12-01
申请号：EP20700744.4
申请日：2020-01-21
Applicant: InterAx Biotech AG , Paul Scherrer Institut
Inventor： MEGER, Benoit , OSTERMAIER, Martin, Konrad , WALDHOER, Maria , BERGER, Philipp , ZIMMERMANN, Mirjam
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公开(公告)号：EP3878447A1
公开(公告)日：2021-09-15
申请号：EP20162433.5
申请日：2020-03-11
Applicant: InterAx Biotech AG
Inventor： Waldhoer, Maria , Zenone, Luca , Wilhelm, Florian , Zimmermann, Mirjam , Ostermaier, Martin Konrad , Scharf, Magdalena Martina , Kolb, Peter
Abstract: The present invention relates to a β-adrenergic receptor antagonist and provides compositions and pharmaceutical compositions for the treatment, amelioration and / or prevention of disease.
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