Abstract:
The present invention provides a novel linker compound which minimizes any nonspecific hydrophobic interactions and is capable of easily adjusting the length to a disulfide group subjected to metal bond to thereby enable effective formation of a metal-sulfur bond; novel ligand conjugate and ligand carrier, and a process for producing them. The linker compound is of a structure represented by the following general formula (1) (see formula 1) where a, b, d, e are independently an integer of 0 to 6. X has a structure serving as a multi-branched structure moiety including three or more hydrocarbon derivative chains, wherein the hydrocarbon derivative chains each include an aromatic amino group at an end thereof, and may or may not include a carbon-nitrogen bond in a main chain thereof. The ligand conjugate includes the linker compound having a sugar molecule introduced therein.
Abstract:
A linker compound having a structure represented by the following general formula (1): (1) wherein n is an integer of 1 to 6, and wherein X has a structure being a multi-branched structure moiety comprising three or four hydrocarbon chains which has an aromatic amino group at the terminal thereof and may contain a carbon-nitrogen bond in the main chain thereof; and a ligand which comprises the linker compound and a saccharide introduced therein.
Abstract:
A versatile linker compound has a structure represented by the following general formula (1), wherein Y has a structure represented by 0 or NH, and X has a structure serving as a multi-branched moiety including four hydrocarbon derivative chains each of which has an aromatic amino group at an end thereof, and may or may not have a carbon-nitrogen bond in a backbone thereof. With the versatile linker compound, sugar molecules can be two-dimensionally arranged on a surface of a protein-analyzing supporter with high reproducibility. Also, a ligand includes the versatile linker compound and a sugar molecule introduced thereinto.
Abstract:
Described herein are pharmaceutical compositions capable of blocking entry of a virus into a host cell and containing one or more compounds of the general formula I or a pharmaceutically acceptable derivative thereof and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat viral infections.
Abstract:
The present invention relates to antibodies which bind human ghrelin and their use in methods of treating or preventing reduced appetite. The invention further relates to diagnostic tools for determining whether an individual is likely to respond to a method of treating or preventing reduced appetite.
Abstract:
The Present Invention provides a heat pipe and an electronic device which can efficiently cool a light emitting element arranged in an end portion, so that it is possible to efficiently mount the heat pipe in a narrow space. The heat pipe is provided with an upper plate (3), a lower plate (4) opposing the upper plate (3), one intermediate plate or a plurality of intermediate plates (5) laminated between the upper plate (3) and the lower plate (4), a main body portion (2) formed by lamination of the upper plate (3), the lower plate (4) and the intermediate plate (5) and capable of sealing a cooling medium, a vapor diffusion path (6) capable of diffusing a vaporized cooling medium, and a capillary flow path (7) capable of reflowing a condensed cooling medium, and the vapor diffusion path (6) is formed from a first end portion (15) of the main body portion toward a second end portion (16) opposing the first end portion (15).
Abstract in simplified Chinese:提供一种小型、重量轻且可以高亮度发光的照明设备。在照明设备(1)中,包括:发光单元(2);导热板(6),其与发光单元(2)传热地接触,扩散从发光单元(2)传来的热;热管(9),其一端与导热板(6)传热地接触,把热从上述一端输送到另一端;以及下部冷却片列(10)和上部冷却片列(11),其与热管(9)的另一端传热地接触,把从热管(9)传来的热发散到环境中。
Abstract in simplified Chinese:在借由对形成于加热基板(3)上之加热薄膜(7)通电而发热之加热设备(1)中,设有加热基板(3)、复数个加热薄膜(7)以及分别对该复数个加热薄膜(7)独立供电之供电端子(8)。并且,于加热薄膜(7)之底面形成复数个传感薄膜9。另外,设置并保持加热基板(3),并设有安装基板(4),其上形成加热薄膜(7)、以及使加热薄膜(7)和外部机器电性连接之供电用配线薄膜(10)及传感用配线薄膜(11)。