公开(公告)号：WO2014168953A1

公开(公告)日：2014-10-16

申请号：PCT/US2014/033343

申请日：2014-04-08

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION ,  KC CENTER FOR TECHNOLOGY COMMERCIALIZATION ,  YAN, Ziying ,  ENGELHARDT, John F. ,  QIU, Jianming

Inventor： YAN, Ziying ,  ENGELHARDT, John F. ,  QIU, Jianming

IPC: A61K39/23

CPC classification number: C12N7/00 ,  A61K39/00 ,  A61K39/23 ,  A61K2039/5256 ,  C07K14/435 ,  C12N15/86 ,  C12N15/8645 ,  C12N2750/14111 ,  C12N2750/14121 ,  C12N2750/14132 ,  C12N2750/14143 ,  C12N2750/14144 ,  C12N2750/14145 ,  C12N2750/14322 ,  C12N2750/14333 ,  C12N2810/6027

Abstract: The invention provides an isolated chimeric virus comprising bocavirus capsid protein and a recombinant adeno-associated viral (AAV) genome, an isolated rBoV comprising human bocavirus capsid protein and a recombinant BoV genome, and uses therefor.

Abstract translation: 本发明提供了包含bocavirus衣壳蛋白和重组腺相关病毒（AAV）基因组的分离的嵌合病毒，包含人bocavirus衣壳蛋白和重组BoV基因组的分离的rBoV，并且用于其。