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公开(公告)号：WO2008128028A2
公开(公告)日：2008-10-23
申请号：PCT/US2008/060010
申请日：2008-04-11
Applicant: DR. REDDY'S LABORATORIES LTD. , DR. REDDY'S LABORATORIES, INC. , KHARWADE, Pramod , SNEHALATHA, Movva , PATIL, Atul Vishvanath , VISHWANATHAN, Narayanan Badri , BHUSHAN, Indu , SREEDHARALA, Venkata Nookaraju , BHAGWATWAR, Harshal Prabhakar , DEVARAKONDA, Surya Narayana , KOMAREDDY, Ravi Kumar , MOHAMMED, Azeezulla Baig , TUMMALA, Arjun Kumar , LILAKAR, Jaydeepkumar Dahyabhai , KIKKURU, Srirami Reddy , DUDIPALA, Swarupa
Inventor： KHARWADE, Pramod , SNEHALATHA, Movva , PATIL, Atul Vishvanath , VISHWANATHAN, Narayanan Badri , BHUSHAN, Indu , SREEDHARALA, Venkata Nookaraju , BHAGWATWAR, Harshal Prabhakar , DEVARAKONDA, Surya Narayana , KOMAREDDY, Ravi Kumar , MOHAMMED, Azeezulla Baig , TUMMALA, Arjun Kumar , LILAKAR, Jaydeepkumar Dahyabhai , KIKKURU, Srirami Reddy , DUDIPALA, Swarupa
IPC: A61K9/14 , A61K31/439 , A61K31/4725 , A61P13/10
CPC classification number: A61K31/439 , A61K9/145 , A61K9/146 , A61K9/1611 , A61K9/1694 , A61K9/2054 , A61K9/2077 , A61K9/4858 , A61K31/4725 , A61K47/40
Abstract: Compositions and/or formulations comprising solifenacin or a salt thereof and processes for preparing the same. Certain compositions and formulations contain a stable amorphous form of solifenacin succinate.
Abstract translation: 包含索非那新或其盐的组合物和/或制剂及其制备方法。 某些组合物和制剂含有稳定的无定形形式的solifenacin琥珀酸酯。
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公开(公告)号：WO2011037976A3
公开(公告)日：2011-08-25
申请号：PCT/US2010049785
申请日：2010-09-22
Applicant: REDDYS LAB LTD DR , REDDYS LAB INC DR , MOVVA SNEHALATHA , JOSHI HEMANTH PRAKASH , KHARWADE PRAMOD , NARAYANAN BADRI VISHWANATHAN , MOLUGU PRASHANTH REDDY , VURE PRASAD , SHAREEF MD AJMAL , VYSYARAJU NAGESWARA RAO , SINGH PREM PRAKASH , YEOLA BHUSHAN SUBHASH , BHAGWATWAR HARSHAL PRABHAKAR
Inventor： MOVVA SNEHALATHA , JOSHI HEMANTH PRAKASH , KHARWADE PRAMOD , NARAYANAN BADRI VISHWANATHAN , MOLUGU PRASHANTH REDDY , VURE PRASAD , SHAREEF MD AJMAL , VYSYARAJU NAGESWARA RAO , SINGH PREM PRAKASH , YEOLA BHUSHAN SUBHASH , BHAGWATWAR HARSHAL PRABHAKAR
CPC classification number: A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2068 , A61K9/2095 , A61K31/428
Abstract: Aspects of the present application relate to pharmaceutical formulations comprising pramipexole or pharmaceutically acceptable salts thereof, methods for manufacturing the same, and uses thereof. Further aspects relate to stable extended release formulations for oral administration comprising pramipexole or pharmaceutically acceptable salts thereof and microcrystalline cellulose, methods for manufacturing the same, and uses thereof.
Abstract translation: 本申请的方面涉及包含普拉克索或其药学上可接受的盐的药物制剂，其制备方法及其用途。 其它方面涉及用于口服给药的稳定的延长释放制剂，其包含普拉克索或其药学上可接受的盐和微晶纤维素，其制备方法及其用途。
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3.发明申请A PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF BETA BLOCKER AND AN ACE INHIBITOR 审中-公开包含BETA阻断剂与ACE抑制剂组合的药物组合物
公开(公告)号：WO2007010501A2
公开(公告)日：2007-01-25
申请号：PCT/IB2006/052513
申请日：2006-07-21
Applicant: RANBAXY LABORATORIES LIMITED , KHARWADE, Pramod , CHAWLA, Manish , RAGHUVANSHI, Rajeev, Singh , RAMPAL, Ashok
Inventor： KHARWADE, Pramod , CHAWLA, Manish , RAGHUVANSHI, Rajeev, Singh , RAMPAL, Ashok
IPC: A61K31/135 , A61K31/403 , A61K9/48 , A61P9/00 , A61P9/12
CPC classification number: A61K9/5078 , A61K9/2081 , A61K9/209 , A61K9/4808 , A61K31/135 , A61K31/138 , A61K31/403
Abstract: A once a day pharmaceutical composition for use in the treatment of cardiovascular disorders includes (a) a first active ingredient comprising a beta blocker; (b) a second active ingredient comprising an ACE inhibitor; and (c) optionally one or more pharmaceutically acceptable excipients. The beta blocker is present in an extended release form and the ACE inhibitor is present in an immediate release form.
Abstract translation: 每天一次用于治疗心血管疾病的药物组合物包括（a）包含β阻断剂的第一活性成分; （b）包含ACE抑制剂的第二活性成分; 和（c）任选的一种或多种药学上可接受的赋形剂。 β受体阻滞剂以延长释放形式存在，ACE抑制剂以即时释放形式存在。
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公开(公告)号：WO2011037976A2
公开(公告)日：2011-03-31
申请号：PCT/US2010/049785
申请日：2010-09-22
Applicant: DR. REDDY'S LABORATORIES LIMITED , DR. REDDY'S LABORATORIES, INC. , MOVVA, Snehalatha , JOSHI, Hemanth, Prakash , KHARWADE, Pramod , NARAYANAN, Badri, Vishwanathan , MOLUGU, Prashanth, Reddy , VURE, Prasad , SHAREEF MD, Ajmal , VYSYARAJU, Nageswara, Rao , SINGH, Prem, Prakash , YEOLA, Bhushan, Subhash , BHAGWATWAR, Harshal, Prabhakar
Inventor： MOVVA, Snehalatha , JOSHI, Hemanth, Prakash , KHARWADE, Pramod , NARAYANAN, Badri, Vishwanathan , MOLUGU, Prashanth, Reddy , VURE, Prasad , SHAREEF MD, Ajmal , VYSYARAJU, Nageswara, Rao , SINGH, Prem, Prakash , YEOLA, Bhushan, Subhash , BHAGWATWAR, Harshal, Prabhakar
CPC classification number: A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2068 , A61K9/2095 , A61K31/428
Abstract: Aspects of the present application relate to pharmaceutical formulations comprising pramipexole or pharmaceutically acceptable salts thereof, methods for manufacturing the same, and uses thereof. Further aspects relate to stable extended release formulations for oral administration comprising pramipexole or pharmaceutically acceptable salts thereof and microcrystalline cellulose, methods for manufacturing the same, and uses thereof.
Abstract translation: 本申请的方面涉及包含普拉克索或其药学上可接受的盐的药物制剂，其制备方法及其用途。 其它方面涉及用于口服给药的稳定的延长释放制剂，包括普拉克索或其药学上可接受的盐和微晶纤维素，其制备方法及其用途。
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Patent Agency Ranking5.发明申请A PROCESS FOR THE PREPARATION OF CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION OF METOPROLOL 审中-公开制备金属醇的控释药物组合物的方法
公开(公告)号：WO2005084636A2
公开(公告)日：2005-09-15
申请号：PCT/IB2005/000501
申请日：2005-02-25
Applicant: RANBAXY LABORATORIES LIMITED , RAGHUVANSHI, Rajeev, Singh , KHARWADE, Pramod , MANDAOGADE, Prashant, Manohar , RAMPAL, Ashok
Inventor： RAGHUVANSHI, Rajeev, Singh , KHARWADE, Pramod , MANDAOGADE, Prashant, Manohar , RAMPAL, Ashok
IPC: A61K9/00
CPC classification number: A61K31/138 , A61K9/2081 , A61K9/5042 , A61K9/5078
Abstract: The present invention relates to processes for preparing an oral controlled-release pharmaceutical composition of metoprolol succinate comprising a plurality of beads, which comprise a water soluble or water swellable inert core. Further, the present invention relates to processes of preparing oral controlled-release pharmaceutical compositions of metoprolol succinate comprising a plurality of beads, which comprise an inert core and one or more drug layers comprising metoprolol, wherein the soluble component of inert core and one or more drug layers comprise less than 95% w/w of a salt of metoprolol.
Abstract translation: 本发明涉及制备包含多个珠粒的美托洛尔琥珀酸酯的口服缓释药物组合物的方法，其包含水溶性或水可溶胀的惰性核。 此外，本发明涉及制备包含多个珠粒的口服缓释药物组合物的方法，其包含惰性核心和包含美托洛尔的一种或多种药物层，其中惰性核心的可溶组分和一种或多种 药物层包含小于95％w / w的美托洛尔盐。
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公开(公告)号：WO2008128028A3
公开(公告)日：2009-02-12
申请号：PCT/US2008060010
申请日：2008-04-11
Applicant: REDDYS LAB LTD DR , REDDYS LAB INC DR , KHARWADE PRAMOD , SNEHALATHA MOVVA , PATIL ATUL VISHVANATH , VISHWANATHAN NARAYANAN BADRI , BHUSHAN INDU , SREEDHARALA VENKATA NOOKARAJU , BHAGWATWAR HARSHAL PRABHAKAR , DEVARAKONDA SURYA NARAYANA , KOMAREDDY RAVI KUMAR , MOHAMMED AZEEZULLA BAIG , TUMMALA ARJUN KUMAR , LILAKAR JAYDEEPKUMAR DAHYABHAI , KIKKURU SRIRAMI REDDY , DUDIPALA SWARUPA
Inventor： KHARWADE PRAMOD , SNEHALATHA MOVVA , PATIL ATUL VISHVANATH , VISHWANATHAN NARAYANAN BADRI , BHUSHAN INDU , SREEDHARALA VENKATA NOOKARAJU , BHAGWATWAR HARSHAL PRABHAKAR , DEVARAKONDA SURYA NARAYANA , KOMAREDDY RAVI KUMAR , MOHAMMED AZEEZULLA BAIG , TUMMALA ARJUN KUMAR , LILAKAR JAYDEEPKUMAR DAHYABHAI , KIKKURU SRIRAMI REDDY , DUDIPALA SWARUPA
IPC: A61K9/14 , A61K31/439 , A61K31/4725 , A61P13/10
CPC classification number: A61K31/439 , A61K9/145 , A61K9/146 , A61K9/1611 , A61K9/1694 , A61K9/2054 , A61K9/2077 , A61K9/4858 , A61K31/4725 , A61K47/40
Abstract: Compositions and/or formulations comprising solifenacin or a salt thereof and processes for preparing the same. Certain compositions and formulations contain a stable amorphous form of solifenacin succinate.
Abstract translation: 包含索非那新或其盐的组合物和/或制剂及其制备方法。 某些组合物和制剂含有稳定的无定形形式的solifenacin琥珀酸酯。
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7.发明申请A PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF BETA BLOCKER AND AN ACE INHIBITOR 审中-公开包含BETA阻断剂与ACE抑制剂组合的药物组合物
公开(公告)号：WO2007010501A3
公开(公告)日：2008-03-20
申请号：PCT/IB2006052513
申请日：2006-07-21
Applicant: RANBAXY LAB LTD , KHARWADE PRAMOD , CHAWLA MANISH , RAGHUVANSHI RAJEEV SINGH , RAMPAL ASHOK
Inventor： KHARWADE PRAMOD , CHAWLA MANISH , RAGHUVANSHI RAJEEV SINGH , RAMPAL ASHOK
IPC: A61K9/50 , A61K9/20 , A61K9/48 , A61K31/138 , A61K31/403
CPC classification number: A61K9/5078 , A61K9/2081 , A61K9/209 , A61K9/4808 , A61K31/135 , A61K31/138 , A61K31/403
Abstract: A once a day pharmaceutical composition for use in the treatment of cardiovascular disorders includes (a) a first active ingredient comprising a beta blocker; (b) a second active ingredient comprising an ACE inhibitor; and (c) optionally one or more pharmaceutically acceptable excipients. The beta blocker is present in an extended release form and the ACE inhibitor is present in an immediate release form.
Abstract translation: 每天一次用于治疗心血管疾病的药物组合物包括（a）包含β阻断剂的第一活性成分; （b）包含ACE抑制剂的第二活性成分; 和（c）任选的一种或多种药学上可接受的赋形剂。 β受体阻滞剂以延长释放形式存在，ACE抑制剂以即时释放形式存在。
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8.发明申请A PROCESS FOR THE PREPARATION OF CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION OF METOPROLOL 审中-公开制备金属醇的控释药物组合物的方法
公开(公告)号：WO2005084636A3
公开(公告)日：2006-11-30
申请号：PCT/IB2005000501
申请日：2005-02-25
Applicant: RANBAXY LAB LTD , RAGHUVANSHI RAJEEV SINGH , KHARWADE PRAMOD , MANDAOGADE PRASHANT MANOHAR , RAMPAL ASHOK
IPC: A61K9/50 , A61K9/00 , A61K9/20 , A61K31/138
CPC classification number: A61K31/138 , A61K9/2081 , A61K9/5042 , A61K9/5078
Abstract: The present invention relates to processes for preparing an oral controlled-release pharmaceutical composition of metoprolol succinate comprising a plurality of beads, which comprise a water soluble or water swellable inert core. Further, the present invention relates to processes of preparing oral controlled-release pharmaceutical compositions of metoprolol succinate comprising a plurality of beads, which comprise an inert core and one or more drug layers comprising metoprolol, wherein the soluble component of inert core and one or more drug layers comprise less than 95% w/w of a salt of metoprolol.
Abstract translation: 本发明涉及制备包含多个珠粒的美托洛尔琥珀酸酯的口服缓释药物组合物的方法，其包含水溶性或水可溶胀的惰性核。 此外，本发明涉及制备包含多个珠粒的口服缓释药物组合物的方法，其包含惰性核心和包含美托洛尔的一种或多种药物层，其中惰性核心的可溶组分和一种或多种 药物层包含小于95％w / w的美托洛尔盐。
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公开(公告)号：WO2005023221A1
公开(公告)日：2005-03-17
申请号：PCT/IB2004/002867
申请日：2004-09-03
Applicant: RANBAXY LABORATORIES LIMITED , KHARWADE, Pramod , RAGHUVANSHI, Rajeev , RAMPAL, Ashok
Inventor： KHARWADE, Pramod , RAGHUVANSHI, Rajeev , RAMPAL, Ashok
IPC: A61K9/14
CPC classification number: A61K9/146 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2077
Abstract: The technical field of the invention relates to solid pharmaceutical compositions of clarithromycin with enhanced absorption and dissolution characteristics provided by micronizing the clarithromycin and one or more wetting agents.
Abstract translation: 本发明的技术领域涉及克拉霉素的固体药物组合物，其具有通过使克拉霉素和一种或多种润湿剂微粉化而提供的增强的吸收和溶解特性。
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