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公开(公告)号：WO2012065043A9
公开(公告)日：2012-12-20
申请号：PCT/US2011060338
申请日：2011-11-11
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
Inventor： FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了用于表征修饰的核酸的方法，组合物和系统。 在某些优选的实施方案中，提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰包括化学修饰的碱基，酶修饰的碱基，无碱基位点，非天然碱基，二级结构和与模板核酸结合的试剂。
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公开(公告)号：WO2012065043A3
公开(公告)日：2012-08-16
申请号：PCT/US2011060338
申请日：2011-11-11
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
Inventor： FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了方法，组合物和系统用于表征修饰的核酸。 在某些优选实施方案中，提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰物包括化学修饰的碱基，酶修饰的碱基，脱碱基位点，非天然碱基，二级结构和与模板核酸结合的试剂。
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3.发明申请METHOD, SYSTEM AND GRAPHICAL USER INTERFACE FOR PROVIDING REVIEWS FOR A PRODUCT 审中-公开方法，系统和图形用户界面提供产品评论
公开(公告)号：WO2006065546A2
公开(公告)日：2006-06-22
申请号：PCT/US2005043459
申请日：2005-11-30
Applicant: GOOGLE INC , RUHL JAN M , DATAR MAYUR D , LEE JESSICA Y
Inventor： RUHL JAN M , DATAR MAYUR D , LEE JESSICA Y
CPC classification number: G06Q30/02
Abstract: The embodiments disclosed herein include new, more efficient ways to collect product reviews from the Internet, aggregate reviews for the same product, and provide an aggregated review to end users in a searchable format. One aspect of the invention is a graphical user interface on a computer that includes a plurality of portions of reviews for a product and a search input area for entering search terms to search for reviews of the product that contain the search terms.
Abstract translation: 本文公开的实施例包括从因特网收集产品评论的新的，更有效的方式，对同一产品的综合评论，并以可搜索的格式向最终用户提供综合审查。 本发明的一个方面是计算机上的图形用户界面，其包括用于产品的多个评论部分和用于输入搜索项以搜索包含搜索项的产品的评论的搜索输入区域。
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Patent Agency Ranking
公开(公告)号：WO2012065043A2
公开(公告)日：2012-05-18
申请号：PCT/US2011/060338
申请日：2011-11-11
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FLUSBERG, Benjamin , KORLACH, Jonas , WEGENER, Jeffrey , CLARK, Tyson, A. , VILFAN, Igor , KISLYUK, Andrey , TURNER, Stephen , SORENSON, Jon , TRAVERS, Kevin , HEINER, Cheryl , TOMANEY, Austin, B. , MARKS, Patrick , LEE, Jessica , JIA, Lei , WEBSTER, Dale , LYLE, John , HANES, Jeremiah , PUGLISI, Joseph
Inventor： FLUSBERG, Benjamin , KORLACH, Jonas , WEGENER, Jeffrey , CLARK, Tyson, A. , VILFAN, Igor , KISLYUK, Andrey , TURNER, Stephen , SORENSON, Jon , TRAVERS, Kevin , HEINER, Cheryl , TOMANEY, Austin, B. , MARKS, Patrick , LEE, Jessica , JIA, Lei , WEBSTER, Dale , LYLE, John , HANES, Jeremiah , PUGLISI, Joseph
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了用于表征修饰的核酸的方法，组合物和系统。 在某些优选的实施方案中，提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰包括化学修饰的碱基，酶修饰的碱基，无碱基位点，非天然碱基，二级结构和与模板核酸结合的试剂。
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公开(公告)号：WO2010068289A2
公开(公告)日：2010-06-17
申请号：PCT/US2009/006517
申请日：2009-12-10
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
Inventor： FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q2561/113 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
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公开(公告)号：WO2010068289A3
公开(公告)日：2010-10-14
申请号：PCT/US2009006517
申请日：2009-12-10
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , TURNER STEPHEN , LEE JESSICA , JIA LEI , KORLACH JONAS , SORENSON JON , WEBSTER DALE , LYLE JOHN , TRAVERS KEVIN , HANES JEREMIAH
Inventor： FLUSBERG BENJAMIN , TURNER STEPHEN , LEE JESSICA , JIA LEI , KORLACH JONAS , SORENSON JON , WEBSTER DALE , LYLE JOHN , TRAVERS KEVIN , HANES JEREMIAH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q2561/113 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了方法，组合物和系统用于表征修饰的核酸。 在某些优选实施方案中，提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰物包括化学修饰的碱基，酶修饰的碱基，脱碱基位点，非天然碱基，二级结构和与模板核酸结合的试剂。
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公开(公告)号：WO2012166934A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/040231
申请日：2012-05-31
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SCHUMACHER, Mark A. , THEODORE, Pierre R. , DESAI, Tejal Ashwin , DINAKAR, Hariharasudhan Chirra , CHU, Catherine , EILERS, Helge , LEE, Jessica , ZAVALA, Kathryn
Inventor： SCHUMACHER, Mark A. , THEODORE, Pierre R. , DESAI, Tejal Ashwin , DINAKAR, Hariharasudhan Chirra , CHU, Catherine , EILERS, Helge , LEE, Jessica , ZAVALA, Kathryn
IPC: A61K31/495
CPC classification number: A61K31/495 , A61K31/122 , A61K45/06 , A61K2300/00
Abstract: The present disclosure provides compositions and methods for use in the treatment of pain, wherein the compounds useful in such compositions and methods inhibit activity of transient receptor potential cation channel subfamily V member 1 (TRPV1) transcription factors, which in some embodiments may be administered in combination with a compound that modulates the activity of TRPV1.
Abstract translation: 本公开提供了用于治疗疼痛的组合物和方法，其中可用于该组合物和方法的化合物抑制瞬时受体潜在阳离子通道亚族V成员1（TRPV1）转录因子的活性，其在一些实施方案中可以以 与调节TRPV1活性的化合物组合。
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公开(公告)号：WO2006065546A3
公开(公告)日：2006-06-22
申请号：PCT/US2005/043459
申请日：2005-11-30
Applicant: GOOGLE, INC. , RUHL, Jan, M. , DATAR, Mayur, D. , LEE, Jessica, Y.
Inventor： RUHL, Jan, M. , DATAR, Mayur, D. , LEE, Jessica, Y.
IPC: G06F17/30
Abstract: The embodiments disclosed herein include new, more efficient ways to collect product reviews from the Internet, aggregate reviews for the same product, and provide an aggregated review to end users in a searchable format. One aspect of the invention is a graphical user interface on a computer that includes a plurality of portions of reviews for a product and a search input area for entering search terms to search for reviews of the product that contain the search terms.
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