公开(公告)号：WO2013030707A1

公开(公告)日：2013-03-07

申请号：PCT/IB2012/054169

申请日：2012-08-16

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  MALLYA, Yogisha ,  BZDUSEK, Karl Antonin

Inventor： MALLYA, Yogisha ,  BZDUSEK, Karl Antonin

IPC: G06T7/00 ,  A61N5/10

CPC classification number: G06T7/0012 ,  A61N5/103 ,  G06F3/0481 ,  G06F3/04845 ,  G06T7/30 ,  G06T2200/24 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/20012 ,  G06T2207/20104 ,  G06T2207/30096

Abstract: Adeformation vector field (DVF) (22)is computed that relatively spatially registers a first image (16)and a second image (14). A contour (26)delineating a structure in the first image is adapted using the DVF to generate an initial contour (52)for the structure in the second image. A final contour (56)is received for the structure in the second image. The DVF is corrected based on the initial and final contours for the structure in the second image to generate a corrected DVF (32).The correction may comprise computing an adjustment DVF (62)relating the initial and final contoursand combining the DVF and the adjustment DVF to generate the corrected DVF.The final contour may be received by displaying the second image overlaid with the initial contour, and receiving user adjustments of the overlaid contour withthe overlaid contour updated for each received user adjustment.

Abstract translation: 计算相对空间地登记第一图像（16）和第二图像（14）的信息矢量场（DVF）（22）。 使用DVF来适应描绘第一图像中的结构的轮廓（26），以生成第二图像中的结构的初始轮廓（52）。 接收第二图像中的结构的最终轮廓（56）。 基于第二图像中的结构的初始和最终轮廓来校正DVF以产生校正的DVF（32）。校正可以包括计算与初始和最终轮廓相关联的调整DVF（62），并将DVF和调整 DVF以产生校正的DVF。可以通过显示覆盖有初始轮廓的第二图像来接收最终轮廓，并且接收用于对每个接收的用户调整更新的重叠轮廓的用户调整。

公开(公告)号：WO2012017375A3

公开(公告)日：2012-02-09

申请号：PCT/IB2011/053411

申请日：2011-08-01

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY AND STANDARDS GMBH ,  BYSTROV, Daniel ,  SCHADEWALDT, Nicole ,  SCHULZ, Heinrich ,  VIK, Torbjoern ,  KUMAR, Prashant ,  MALLYA, Yogisha

Inventor： BYSTROV, Daniel ,  SCHADEWALDT, Nicole ,  SCHULZ, Heinrich ,  VIK, Torbjoern ,  KUMAR, Prashant ,  MALLYA, Yogisha

IPC: G06T7/00 ,  G06T19/20

Abstract: Interactive mesh deformation for in-plane 3D segmentation / delineation for radiation therapy planning done on a slice by slice basis of a region / a volume of interest (VOI, ROI). Segmentation starts by some automatic 3D algorithm approximating the organ surface roughly by some triangular surface mesh which mesh is afterwards manually refined by the user who deforms it to bring it closer to the region of interest. The deformation is an invertible, i.e. one-to-one, mapping avoiding self - intersections of the deformed mesh thereby preserving the topology of the anatomy. The deformation mapping involves a Gaussian function (Gaussian deformation kernel) restricting the deformation to a local region. The user picks with the pointer a start point on a selected image slice through the volume and moves it to some end point. The distance the mesh vertices move decreases exponentially with the distance to the start point. Additionally, surface mesh resolution is increased by iteratively subdividing mesh triangles in the vicinity of a user- selected contour in a surface mesh until every pixel or voxel contains at least one triangle vertex.

公开(公告)号：WO2012080949A1

公开(公告)日：2012-06-21

申请号：PCT/IB2011/055638

申请日：2011-12-13

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  MALLYA, Yogisha ,  POSTON, Timothy

Inventor： MALLYA, Yogisha ,  POSTON, Timothy

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06T7/30 ,  G06T2207/10072

Abstract: A method includes obtaining first volumetric image data, which is acquired at a first time, including a region of interest with a structural feature located at a first position. The method further includes obtaining second volumetric image data, which is acquired at a second different time, including the region of interest with the structural feature located at a second different position. The method further includes determining a registration transformation that registers the first and second volumetric image data such that the at least one structural feature in the first volumetric image data aligns with the at least one structural feature in the second volumetric image data. The registration transformation is based at least on a contour guided deformation registration. The method further includes generating a signal indicative of the registration transformation.

Abstract translation: 一种方法包括获得第一时间获取的第一体积图像数据，其包括具有位于第一位置的结构特征的感兴趣区域。 该方法还包括获得在第二不同时间获取的第二体积图像数据，所述第二体积图像数据包括位于第二不同位置处的结构特征的感兴趣区域。 该方法还包括确定注册变换，其注册第一和第二体积图像数据，使得第一体积图像数据中的至少一个结构特征与第二体积图像数据中的至少一个结构特征对齐。 注册变换至少基于轮廓引导变形配准。 该方法还包括产生指示登记变换的信号。

公开(公告)号：WO2012017375A2

公开(公告)日：2012-02-09

申请号：PCT/IB2011053411

申请日：2011-08-01

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  BYSTROV DANIEL ,  SCHADEWALDT NICOLE ,  SCHULZ HEINRICH ,  VIK TORBJOERN ,  KUMAR PRASHANT ,  MALLYA YOGISHA

Inventor： BYSTROV DANIEL ,  SCHADEWALDT NICOLE ,  SCHULZ HEINRICH ,  VIK TORBJOERN ,  KUMAR PRASHANT ,  MALLYA YOGISHA

IPC: G06T19/00

CPC classification number: G06T15/00 ,  G06T7/10 ,  G06T7/11 ,  G06T7/149 ,  G06T19/20 ,  G06T2207/10072 ,  G06T2210/41 ,  G06T2219/2021

Abstract: When segmenting a surface mesh diagnostic image, invertible transformations are facilitated by adjusting a Gaussian kernel size on the fly. Kernel size is adjusted as a function of distance traveled by a cursor during user selection of a contour to be adjusted. Additionally, surface mesh resolution is increased by iteratively subdividing mesh triangles (242) in the vicinity of a user-selected contour in a surface mesh (100, 220, 240, 318) until every pixel or voxel contains at least one triangle vertex. A fuzzy line change (FLC) algorithm (332) is then executed to snap the nearest mesh contour to a user- indicated position.

Abstract translation: 当分割表面网格诊断图像时，通过在飞行中调整高斯内核大小来促进可逆转换。 在用户选择要调整的轮廓的过程中，内核大小作为光标行进的距离的函数进行调整。 此外，通过在表面网格（100,220,240,318）中的用户选择的轮廓附近迭代地分割网格三角形（242）直到每个像素或体素包含至少一个三角形顶点，来增加表面网格分辨率。 然后执行模糊线变化（FLC）算法（332）以将最近的网格轮廓捕捉到用户指示的位置。

公开(公告)号：WO2011073879A3

公开(公告)日：2011-09-01

申请号：PCT/IB2010055768

申请日：2010-12-13

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  KUMAR PRASHANT ,  SANJAYA KUMARA ,  VENKATESAN SOURI RAJAN ,  MALLYA YOGISHA

Inventor： KUMAR PRASHANT ,  SANJAYA KUMARA ,  VENKATESAN SOURI RAJAN ,  MALLYA YOGISHA

IPC: A61B7/04 ,  G06F19/00

CPC classification number: A61B7/04 ,  A61B5/0452 ,  A61B7/005

Abstract: The present invention refers to a signal processing apparatus and its method of operation. The apparatus comprises a phonocardiogram interface adapted to receive a phonocardiogram signal captured according to a first set of capturing properties, a processor adapted to analyze the phonocardiogram signal to determine an analysis result for the phonocardiogram signal and a confidence value of the determined analysis result, and a flow control adapted to determine, whether a subsequent capture of the phonocardiogram signal according to a second set of capturing properties is likely to improve an accuracy of the determined analysis result. If applicable the flow control coordinates the subsequent capture of the phonocardiogram signal according to the second set of capturing properties. The invention also refers to a corresponding computer program product. Also described is a signal processing apparatus comprising a user interface adapted to present the captured phonocardiogram signal to a user and to receive a user correction. Based on the user correction the phonocardiogram signal may be reanalyzed.

Abstract translation: 本发明涉及一种信号处理装置及其操作方法。 该装置包括适于接收根据第一组捕获属性捕获的心音图信号的心音图界面，适于分析心音图信号以确定心音图信号的分析结果和确定的分析结果的置信度的处理器，以及 流量控制适于确定根据第二组捕获属性的后续的所述心音图信号的捕获是否可能提高所确定的分析结果的准确性。 如果适用，流量控制根据第二组捕获属性协调随后的心音图信号的捕获。 本发明还涉及相应的计算机程序产品。 还描述了一种信号处理装置，其包括适于向用户呈现所捕获的心音图信号并接收用户校正的用户界面。 基于用户校正，可以重新分析心音图信号。

公开(公告)号：WO2011095918A1

公开(公告)日：2011-08-11

申请号：PCT/IB2011/050378

申请日：2011-01-28

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  MALLYA, Yogisha ,  RAMASWAMY, Shivakumar, Kunigal ,  AYYAKAD KRISHNAN, Narayanan ,  ZAGORCHEV, Lyubomir, Georgiev

Inventor： MALLYA, Yogisha ,  RAMASWAMY, Shivakumar, Kunigal ,  AYYAKAD KRISHNAN, Narayanan ,  ZAGORCHEV, Lyubomir, Georgiev

IPC: G06F19/00

CPC classification number: G06F19/321 ,  G06F19/00 ,  G16H10/20

Abstract: A system for processing multi-subject volumes comprises a volume input (1) for receiving an input volume image dataset (13) comprising a plurality of subjects scanned simultaneously. A metadata input (2) receives metadata (15) relating to individual ones of the subjects. A subject finder (3) identifies a plurality of portions of the input volume image dataset (13), each portion comprising one of the subjects. A volume image dataset generator (4) generates a plurality of separate volume image datasets (16), each separate volume image dataset (7) comprising one of the portions of the input volume image dataset. A metadata handler (5) associates the metadata (15) relating to a subject with the separate volume image dataset (7) comprising the portion comprising the subject.

Abstract translation: 一种用于处理多目标体积的系统包括用于接收包括同时扫描的多个被摄体的输入体积图像数据集（13）的体积输入（1）。 元数据输入（2）接收与个体个体有关的元数据（15）。 主体取景器（3）识别输入音量图像数据集（13）的多个部分，每个部分包括其中一个被摄体。 卷图像数据集生成器（4）生成多个单独的卷图像数据集（16），每个单独的卷图像数据集（7）包括输入卷图像数据集的部分之一。 元数据处理程序（5）将与主题相关的元数据（15）与包括该对象的部分的单独的卷图像数据集（7）相关联。

公开(公告)号：WO2011073879A2

公开(公告)日：2011-06-23

申请号：PCT/IB2010/055768

申请日：2010-12-13

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  KUMAR, Prashant ,  SANJAYA, Kumara ,  VENKATESAN, Souri, Rajan ,  MALLYA, Yogisha

Inventor： KUMAR, Prashant ,  SANJAYA, Kumara ,  VENKATESAN, Souri, Rajan ,  MALLYA, Yogisha

IPC: A61B7/04 ,  G06F19/00

CPC classification number: A61B7/04 ,  A61B5/0452 ,  A61B7/005

Abstract: The present invention refers to a signal processing apparatus and its method of operation. The apparatus comprises a phonocardiogram interface adapted to receive a phonocardiogram signal captured according to a first set of capturing properties, a processor adapted to analyze the phonocardiogram signal to determine an analysis result for the phonocardiogram signal and a confidence value of the determined analysis result, and a flow control adapted to determine, whether a subsequent capture of the phonocardiogram signal according to a second set of capturing properties is likely to improve an accuracy of the determined analysis result. If applicable the flow control coordinates the subsequent capture of the phonocardiogram signal according to the second set of capturing properties. The invention also refers to a computer program product comprising instructions that enable a processor to carry out the method of operation of the signal processing apparatus.

Abstract translation: 本发明涉及一种信号处理装置及其操作方法。 该装置包括适于接收根据第一组捕获属性捕获的心音图信号的心音图界面，适于分析心音图信号以确定心音图信号的分析结果和确定的分析结果的置信度的处理器，以及 流量控制适于确定根据第二组捕获属性的后续的所述心音图信号的捕获是否可能提高所确定的分析结果的准确性。 如果适用，流量控制根据第二组捕获属性协调随后的心音图信号的捕获。 本发明还涉及一种计算机程序产品，其包括使处理器能够执行信号处理装置的操作方法的指令。