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公开(公告)号：JP2011505171A
公开(公告)日：2011-02-24
申请号：JP2010528465
申请日：2008-10-10
Applicant: モナ カ テクノロジーMauna Kea Technologies
Inventor： ヴィエルローブ，ベルトラン , ドゥッスー，フランソワ , ブーラロ，ニコラ , ラヴィロニエ，ニコラ , ラコンブ，フランソワ
CPC classification number: G01N21/6458 , A61B1/00165 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/07 , A61B5/0068 , A61B5/0071 , A61B5/0084 , G01N2021/6419 , G01N2021/6421 , G01N2201/024 , G01N2201/0846 , G01N2201/086
Abstract: An imaging device includes an illumination module comprising at least one emitter for emitting at least one excitation beam; a scanning and injection module comprising an image guide, a proximal end and a distal end of which are linked by a plurality of optical fibers; a scanning and injection optical system configured to alternately inject the at least one excitation beam into an optical fiber of the image guide from the proximal end of the image guide; a detection module comprising a detector for detecting a luminous flux collected at the distal end of the image guide, wherein at least one of the illumination module and the detection module is optically conjugated with the scanning and injection module using a conjugating optical fiber.
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公开(公告)号：JP2015006437A
公开(公告)日：2015-01-15
申请号：JP2014186464
申请日：2014-09-12
Applicant: マウナ キア テクノロジーズ , Mauna Kea Technologies , マウナ キア テクノロジーズ
Inventor： BENJAMIN ABRAT , CHARLOTTE CAVE , ALEXANDRE LOISEAU , JEROME LOPEZ , ANNE OSDOIT , BERTRAND VIELLEROBE
CPC classification number: A61B5/0071 , A61B1/043 , A61B1/07 , A61B5/0068 , A61B5/0084 , G01N21/6428 , G01N21/6458 , G01N2021/6484
Abstract: 【課題】費用がかからず且つ組織の画像の迅速な獲得を可能にする生体内イメージングのための簡略化された方法を提案することを課題とする。【解決手段】本発明は、光ビームの走査によって組織を励起する少なくとも一つの光ファイバーを有する獲得システムを使用して、組織から生体内蛍光画像を獲得するための方法に関するものである。本発明に依れば、システムは、組織中に存在するメチレンブルーによって放出される蛍光信号を検知するために使用される。【選択図】図1
Abstract translation: 要解决的问题：提供一种简便的体内成像方法，其便宜并允许快速获取组织成像。解决方案：本发明涉及一种通过使用采集系统从组织获取体内荧光成像的方法，所述采集系统具有 至少一个光纤通过扫描光束激发组织。 根据本发明，该系统用于检测由组织中存在的亚甲基蓝发射的荧光信号。
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公开(公告)号：US10002427B2
公开(公告)日：2018-06-19
申请号：US15028188
申请日：2014-10-13
Applicant: Mauna Kea Technologies
Inventor： Nicolas Linard , Barbara Andre , Julien Dauguet , Tom Vercauteren
CPC classification number: G06T7/0016 , G06T7/174 , G06T2207/10068
Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).
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公开(公告)号：US20180286049A1
公开(公告)日：2018-10-04
申请号：US15997936
申请日：2018-06-05
Applicant: Mauna Kea Technologies
Inventor： Nicolas Linard , Barbara Andre , Julien Dauguet , Tom Vercauteren
Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).
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公开(公告)号：USD1057759S1
公开(公告)日：2025-01-14
申请号：US29904371
申请日：2023-10-05
Applicant: Mauna Kea Technologies
Designer： Francois Lacombe , Margery Rothenberg
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Patent Agency Ranking
公开(公告)号：US09730586B2
公开(公告)日：2017-08-15
申请号：US14731949
申请日：2015-06-05
Applicant: Mauna Kea Technologies
Inventor： Nicolas Boularot , Arnaud Cressant
CPC classification number: A61B5/0084 , A61B1/00154 , A61B1/313 , A61B5/0068 , A61B5/0071 , A61B5/6814 , A61B5/6864 , A61B5/6868 , A61B5/6882 , A61B90/11 , A61B2503/40 , A61B2560/063 , A61B2562/0238 , G02B23/26
Abstract: An intracranial implant to position a fiber bundle to a specified region of a brain of an animal. The implant may include a base support to be fixed to a skull of the animal over an orifice drilled in the skull, a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the animal through the drilled orifice and a first locking member arranged on the base support, to cooperate with a ferrule of the fiber bundle, the first locking member configured to lock the fiber bundle to the specified region of the brain of the animal.
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公开(公告)号：US20180286048A1
公开(公告)日：2018-10-04
申请号：US15997915
申请日：2018-06-05
Applicant: Mauna Kea Technologies
Inventor： Nicolas Linard , Barbara Andre , Julien Dauguet , Tom Vercauteren
Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).
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8.发明申请公开(公告)号：US20160253801A1
公开(公告)日：2016-09-01
申请号：US15028188
申请日：2014-10-13
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： Nicolas Linard , Barbara Andre , Julien Dauguet , Tom Vercauteren
IPC: G06T7/00
CPC classification number: G06T7/0016 , G06T7/174 , G06T2207/10068
Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).
Abstract translation: 根据第一方面，本发明涉及一种通过表征通过视频医疗装置顺序获取的图像来支持临床决定的方法。 该方法包括定义至少一个图像定量标准，对缓冲器中的每个图像（10）存储顺序图像，使用第一算法，基于所述图像定量标准自动确定至少一个输出，并附加所述输出 到时间线（11）。
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9.发明申请CHARACTERIZATION OF BIOLOGICAL TISSUES AT A CELLULAR LEVEL USING RED AND FAR-RED FLUORESCENT DYES 审中-公开使用红色和微红色荧光染料在细胞水平上表征生物组织公开(公告)号：US20150104394A1
公开(公告)日：2015-04-16
申请号：US14401549
申请日：2013-05-17
Applicant: IGR-Institut Gustave Roussy , Mauna Kea Technologies
Inventor： Muriel Abbaci , Odile Casiraghi , Corinne Laplace-Builhe
IPC: A61K49/00
CPC classification number: A61K49/003 , A61B5/0068 , A61B5/0071 , A61B5/443 , A61B5/444 , A61K49/0021 , A61K49/0034 , G01N21/6428 , G01N21/6458
Abstract: A method for observing the morphology of a biological tissue is disclosed. The method involves using a fluorescent dye on the biological tissue, where the fluorescent dye is selected from patent blue V, isosulfan blue, toluidine blue, hypericin, indocyanine green, MVAC, or doxorubicin, and using a microscopic linear or non-linear imaging system to form an image of the biological tissue, where the fluorescence of the dye reveals the morphology of the tissue at cellular scale.
Abstract translation: 公开了一种用于观察生物组织形态的方法。 该方法包括在生物组织上使用荧光染料，其中荧光染料选自专利蓝V，异硫丹蓝，甲苯胺蓝，金丝桃素，吲哚菁绿，MVAC或多柔比星，并使用微观线性或非线性成像系统 以形成生物组织的图像，其中染料的荧光在细胞规模上显示出组织的形态。
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公开(公告)号：US10776920B2
公开(公告)日：2020-09-15
申请号：US15997802
申请日：2018-06-05
Applicant: Mauna Kea Technologies
Inventor： Nicolas Linard , Barbara Andre , Julien Dauguet , Tom Vercauteren
Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).
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