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公开(公告)号：WO2010036311A2
公开(公告)日：2010-04-01
申请号：PCT/US2009/005169
申请日：2009-09-16
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , MAXHAM, Kenneth, Mark , SORENSON, Jon , EID, John , MARKS, Patrick , TRAVERS, Kevin , GRAY, Donald , EMIG, Robin , CHAISSON, Mark , FLUSBERG, Benjamin
Inventor： MAXHAM, Kenneth, Mark , SORENSON, Jon , EID, John , MARKS, Patrick , TRAVERS, Kevin , GRAY, Donald , EMIG, Robin , CHAISSON, Mark , FLUSBERG, Benjamin
IPC: G01N21/00
CPC classification number: C12Q1/6869 , G01N2021/7786 , Y10T436/143333 , C12Q2525/301 , C12Q2533/101 , C12Q2537/149 , C12Q2565/631 , C12Q2525/307 , C12Q2525/191
Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.
Abstract translation: 提供了在分析反应期间进行间歇检测的方法，装置和系统。 这样的方法有助于从不同的反应时间收集反应数据。 此外，这样的方法可用于在给定的反应时间下降低照明分析反应中一种或多种反应物的光诱导损伤。 在优选的实施方案中，将反应混合物经历至少一个照明和非照射期，并允许进行，使得反应混合物被照射的时间小于光诱导的损伤阈值期。
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Patent Agency Ranking2.发明申请METHODS AND PROCESSES FOR CALLING BASES IN SEQUENCE BY INCORPORATION METHODS 审中-公开通过并入方法对序列进行呼叫的方法和过程
公开(公告)号：WO2008154317A1
公开(公告)日：2008-12-18
申请号：PCT/US2008/065996
申请日：2008-06-05
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , MAXHAM, Kenneth, Mark , MURPHY, Devon , HOLDEN, David , HESTER, Kevin , MARKS, Patrick , TOMANEY, Austin, B.
Inventor： MAXHAM, Kenneth, Mark , MURPHY, Devon , HOLDEN, David , HESTER, Kevin , MARKS, Patrick , TOMANEY, Austin, B.
CPC classification number: C12Q1/6869 , G06F19/22 , C12Q2563/107
Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by- incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.
Abstract translation: 计算机实现的方法和执行这样的方法的系统用于处理来自分析操作和系统的信号数据，特别是处理来自逐个并入过程的信号数据，以鉴定模板核酸和较大核酸分子的核苷酸序列，例如基因组或 片段。
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公开(公告)号：WO2010036311A3
公开(公告)日：2010-06-17
申请号：PCT/US2009005169
申请日：2009-09-16
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , MAXHAM KENNETH MARK , SORENSON JON , EID JOHN , MARKS PATRICK , TRAVERS KEVIN , GRAY DONALD , EMIG ROBIN , CHAISSON MARK , FLUSBERG BENJAMIN
Inventor： MAXHAM KENNETH MARK , SORENSON JON , EID JOHN , MARKS PATRICK , TRAVERS KEVIN , GRAY DONALD , EMIG ROBIN , CHAISSON MARK , FLUSBERG BENJAMIN
IPC: G01N21/00
CPC classification number: C12Q1/6869 , G01N2021/7786 , Y10T436/143333 , C12Q2525/301 , C12Q2533/101 , C12Q2537/149 , C12Q2565/631 , C12Q2525/307 , C12Q2525/191
Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.
Abstract translation: 提供了用于在分析反应期间执行间歇检测的方法，装置和系统。 这种方法便于从不同的反应时间收集反应数据。 此外，此类方法可用于减少在给定反应时间下照明分析反应中一种或多种反应物的光致损伤。 在优选的实施方案中，使反应混合物经历至少一个照射和未照射的时间段并使其进行，使得照射反应混合物的时间小于光诱导的损伤阈值时间段。
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公开(公告)号：WO2010036287A1
公开(公告)日：2010-04-01
申请号：PCT/US2009/001927
申请日：2009-03-27
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , MAXHAM, Kenneth, Mark , SORENSON, Jon , EID, John , MARKS, Patrick , TRAVERS, Kevin
Inventor： MAXHAM, Kenneth, Mark , SORENSON, Jon , EID, John , MARKS, Patrick , TRAVERS, Kevin
CPC classification number: C12Q1/6869 , G01N2021/7786 , Y10T436/143333 , C12Q2525/301 , C12Q2533/101 , C12Q2537/149 , C12Q2565/631 , C12Q2525/307 , C12Q2525/191
Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.
Abstract translation: 提供了用于在分析反应期间执行间歇检测的方法，装置和系统。 这种方法便于从不同的反应时间收集反应数据。 此外，此类方法可用于减少在给定反应时间下照明分析反应中一种或多种反应物的光致损伤。 在优选的实施方案中，使反应混合物经受至少一个照射和未照射的时间段并使其进行，使得照射反应混合物的时间小于光致损伤阈值时间。
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公开(公告)号：WO2006015104A3
公开(公告)日：2007-08-02
申请号：PCT/US2005026757
申请日：2005-07-28
Applicant: MIRRA INC , MAXHAM KENNETH MARK
Inventor： MAXHAM KENNETH MARK
IPC: G06F7/04 , G06F15/16 , G06F15/167 , G06F15/173 , G06F17/30 , H04K1/00 , H04L9/32 , H04N7/16
CPC classification number: H04L67/2819 , H04L67/02 , H04L67/14 , H04L67/28 , H04L67/2823
Abstract: A communication system may include a network, a server, and one or more clients. The server may verify that a communication among two or more of the clients should occur. The server may provide linking data to the two or more peers. The two or more client may use the linking data to send and/or receive a communication. The communication system may include a communication linking module that may receive a communication from one client and may send the communication to at least one other client. The communication may comprise content distribution, content synchronization, or another type of communication.
Abstract translation: 通信系统可以包括网络，服务器和一个或多个客户端。 服务器可以验证是否应该发生两个或多个客户端之间的通信。 服务器可以向两个或更多个对等体提供链接数据。 两个或多个客户端可以使用链接数据来发送和/或接收通信。 通信系统可以包括可以从一个客户端接收通信并且可以将通信发送到至少一个其他客户端的通信链接模块。 通信可以包括内容分发，内容同步或另一种类型的通信。
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公开(公告)号：WO2006015104A2
公开(公告)日：2006-02-09
申请号：PCT/US2005/026757
申请日：2005-07-28
Applicant: MIRRA, INC. , MAXHAM, Kenneth, Mark
Inventor： MAXHAM, Kenneth, Mark
IPC: G06F17/30
CPC classification number: H04L67/2819 , H04L67/02 , H04L67/14 , H04L67/28 , H04L67/2823
Abstract: A communication system may include a network, a server, and one or more clients. The server may verify that a communication among two or more of the clients should occur. The server may provide linking data to the two or more peers. The two or more client may use the linking data to send and/or receive a communication. The communication system may include a communication linking module that may receive a communication from one client and may send the communication to at least one other client. The communication may comprise content distribution, content synchronization, or another type of communication.
Abstract translation: 通信系统可以包括网络，服务器和一个或多个客户端。 服务器可以验证是否应该发生两个或多个客户端之间的通信。 服务器可以向两个或更多个对等体提供链接数据。 两个或多个客户端可以使用链接数据来发送和/或接收通信。 通信系统可以包括通信链接模块，其可以从一个客户端接收通信，并且可以将通信发送到至少一个其他客户端。 通信可以包括内容分发，内容同步或另一种类型的通信。
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