中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

6 records (took 0.022 seconds)

    TAGGED POLYMERS, WATER TREATMENT COMPOSITIONS, AND METHODS OF THEIR USE IN AQUEOUS SYSTEMS
    4.
    发明申请
    TAGGED POLYMERS, WATER TREATMENT COMPOSITIONS, AND METHODS OF THEIR USE IN AQUEOUS SYSTEMS 审中-公开
    标签聚合物，水处理组合物及其在水性体系中的使用方法

    公开(公告)号：WO2013025332A1

    公开(公告)日：2013-02-21

    申请号：PCT/US2012/048803

    申请日：2012-07-30

    Applicant: BUCKMAN LABORATORIES INTERNATIONAL, INC. ,  MCNEEL, Thomas, E. ,  WHITTEMORE, Marilyn, S. ,  CLARK, Richard, A. ,  GRABOWICZ, Jadwiga, J.

    Inventor： MCNEEL, Thomas, E. ,  WHITTEMORE, Marilyn, S. ,  CLARK, Richard, A. ,  GRABOWICZ, Jadwiga, J.

    IPC: G01N33/18 ,  C02F5/08 ,  C02F5/14 ,  C09K11/06

    CPC classification number: G01N33/1826 ,  C02F1/008 ,  C02F1/5209 ,  C02F2209/06 ,  C02F2303/20 ,  C09K11/06 ,  G01N33/18 ,  Y02A20/206 ,  Y10S210/917 ,  Y10T436/13

    Abstract: A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomelic unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material in the aqueous system. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.

    Abstract translation: 描述了一种方法和组合物，用于使用标记（荧光）聚合物在含水体系中控制污垢物质如水垢的生长。 标记的聚合物可以是具有至少一种衍生自荧光团的荧光单体单元的荧光聚合物，其具有至少一个包含烯属基团的末端。 控制水性体系中至少一种结垢材料的生长的方法可以包括以下步骤：将标记的聚合物加入待处理的水性体系中，荧光测量监测标记的聚合物的浓度，并根据需要调节浓度 的标记聚合物和成比例地使用的水处理化合物或有效控制水性体系中至少一种结垢材料生长的化合物。 荧光信号测定前pH值的调节可用于提高荧光团的灵敏度，并使背景干扰最小化。

    METHOD AND COMPOSITION TO CONTROL THE GROWTH OF MICROORGANISMS IN AQUEOUS SYSTEMS AND ON SUBSTRATES
    5.
    发明申请
    METHOD AND COMPOSITION TO CONTROL THE GROWTH OF MICROORGANISMS IN AQUEOUS SYSTEMS AND ON SUBSTRATES 审中-公开
    控制水质体系和底物微生物生长的方法与组成

    公开(公告)号：WO2006138271A1

    公开(公告)日：2006-12-28

    申请号：PCT/US2006/022928

    申请日：2006-06-13

    Applicant: BUCKMAN LABORATORIES INTERNATIONAL, INC. ,  ZHOU, Xiangdong ,  BRYANT, Stephen, D. ,  MCNEEL, Thomas, E.

    Inventor： ZHOU, Xiangdong ,  BRYANT, Stephen, D. ,  MCNEEL, Thomas, E.

    IPC: A01N63/02 ,  A01N59/00 ,  A01N59/24 ,  A01P1/00

    CPC classification number: A01N63/02 ,  A01N2300/00

    Abstract: A method and composition for killing, preventing, or inhibiting the growth of microorganisms in an aqueous system or on a substrate capable of supporting a growth of microorganisms are provided by providing a lactoperoxidase, hydrogen peroxide or a peroxide source, a halide, other than a chloride, or a thiocyanate, and, optionally, an ammonium source, under conditions in which the lactoperoxidase, peroxide from the hydrogen peroxide or peroxid Ie source, halide or thiocyanate and ammonium from the ammonium source interact to provide an antimicrobial agent to the aqueous system or substrate.

    Abstract translation: 通过提供乳过氧化物酶，过氧化氢或过氧化物源，卤化物，除了能够支持微生物生长的水系统或基底上的微生物的生长以杀死，预防或抑制微生物的生长的方法和组合物 氯化物或硫氰酸盐，以及任选的铵源，其中乳过氧化物酶，来自过氧化氢或过氧化物源的过氧化物，卤化物或硫氰酸盐和来自铵源的铵相互作用以提供抗微生物剂到水系统 或底物。

    AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF
    6.
    发明申请
    AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF 审中-公开
    AMINO-和MERCURIO-取代的4'，5'-二氢松香油及其治疗用途

    公开(公告)号：WO0031081A3

    公开(公告)日：2000-11-23

    申请号：PCT/US9927739

    申请日：1999-11-24

    Applicant: BUCKMAN LABOR INC ,  HEINDEL NED D ,  LASKIN JEFFREY D ,  HECK DIANE E ,  RAPP ROBERT D ,  MCNEEL THOMAS E ,  JABIN IVAN ,  WHITTEMORE MARILYN S

    Inventor： HEINDEL NED D ,  LASKIN JEFFREY D ,  HECK DIANE E ,  RAPP ROBERT D ,  MCNEEL THOMAS E ,  JABIN IVAN ,  WHITTEMORE MARILYN S

    IPC: A61P17/06 ,  A61P35/00 ,  C07D311/44 ,  C07D311/56 ,  C07D493/04 ,  C07F3/14 ,  A61K31/34

    CPC classification number: C07D493/04 ,  C07D311/44 ,  C07D311/56 ,  C07F3/14

    Abstract: 5'- substituted, 4', 5'- dihydropsoralen compounds (5) bearing tertiary amines (and salts thereof), quaternary ammonium moieties or organomercurial moieties are described. Also described are 2- substituted mercurimethyl -2-3- dihydro -benzofurans of formula (7). Also reported are versatile direct syntheses through a hitherto unknown compounds such as 3-R-4, 8-dimethyl -4',5'-dihydro -5'-bromomethylpsoralen or a 3-R-4, 8-dimethyl-4, 5'-dihydro- 5'-iodomethylpsoralen to prepare a structurally diverse array of partially reduced psoralens and benzofurans. The presence of a permanent ammonium charge in these psoralens precludes membrane passage and the mono-unsaturation precludes the cross linking of nuclear DNA, thereby minimizing the mutagenic/carcinogenic side effects long associated with psoralen-derived therapies. The presence of a mercury functionality provides a reactive cell-binding group on these psoralens with unique cytotoxicity without light activation and an enhancement of cytotoxicity activity upon light activation. The invention also relates to these partially reduced and quaternized psoralens, amino-substituted psoralens, and mercurio psoralens display impressive pharmacology against PAM 212 keratinocytes, a model cell line employed as a test system to indicate epidermal cytotoxicity and cancer. The compounds of the invention also have antimicrobicidal activity useful in pharmacologic agents for mammals (e.g. the treatment of tuberculosis) as well as in controlling the growth of microorganisms on substrates and in aqueous systems.

    Abstract translation: 描述了带有叔胺（及其盐），季铵部分或有机金属部分的5'-取代的，4'，5'-二氢补骨脂化合物（5）。 还描述了式（7）的2-取代的汞甲基-2-3-二氢 - 苯并呋喃。 还报道了通过迄今未知的化合物如3-R-4,8-​​二甲基-4'，5'-二氢-5'-溴甲基补骨脂素或3-R-4,8-​​二甲基-4,5 ' - 二氢-5'-碘甲基补骨脂素以制备结构多样化的部分减少的补骨脂素和苯并呋喃。 这些补骨脂素中永久性铵电荷的存在排除了膜通道，单不饱和度排除了核DNA的交联，从而使与补骨脂素衍生疗法长期相关的致突变/致癌性副作用最小化。 汞功能的存在提供了这些补骨脂素上的反应性细胞结合基团，其具有独特的细胞毒性而没有光激活并且在光活化时增强细胞毒性活性。 本发明还涉及这些部分还原的和季铵化的补骨脂素，氨基取代的补骨脂素和补骨脂素显示出对PAM212角质形成细胞的令人印象深刻的药理学，PAM212角质形成细胞是用作表明表皮细胞毒性和癌症的测试系统的模型细胞系。 本发明化合物还具有抗哺乳动物药理活性剂（例如治疗结核病）以及控制微生物在底物和水系统中生长的抗微生物活性。

Patent Agency Ranking