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    Photoprotective composition comprising synergistic combination of sunscreen active compounds
    1.
    发明专利
    Photoprotective composition comprising synergistic combination of sunscreen active compounds 有权
    包含活性化合物的协同组合的光保护组合物

    公开(公告)号：JP2013040211A

    公开(公告)日：2013-02-28

    申请号：JP2012257351

    申请日：2012-11-26

    Applicant: Msd Consumer Care Inc ,  エムエスディー コンシューマー ケア, インコーポレイテッド

    Inventor： BEASLEY DONATHAN G ,  MEYER THOMAS A

    IPC: A61K8/37 ,  A61K8/02 ,  A61Q5/00 ,  A61Q17/04

    CPC classification number: A61K8/37 ,  A61K8/40 ,  A61K2800/5922 ,  A61Q17/04 ,  A61Q19/04

    Abstract: PROBLEM TO BE SOLVED: To provide compositions for topical application containing the synergistic combination of sunscreen active compounds.SOLUTION: The compositions for topical application to skin and/or hair, comprise photoprotecting synergistically effective amounts of sunscreen active agents, such as octinoxate, octocrylene, and amiloxate. Methods of protecting skin and/or hair against deleterious effects of sunlight/UV radiation by topical application of compositions are also provided. The composition can comprise an anhydrous or aqueous solid or paste, emulsion, suspension, or dispersion.

    Abstract translation: 待解决的问题：提供含有防晒活性化合物的协同组合的局部施用组合物。 用于局部施用于皮肤和/或头发的组合物包含光保护协同有效量的防晒活性剂，例如辛酸，辛酸和氨基甲酸酯。 还提供了通过局部施用组合物来保护皮肤和/或头发免受阳光/紫外线辐射的有害影响的方法。 组合物可以包含无水或水性固体或糊状物，乳液，悬浮液或分散体。 版权所有（C）2013，JPO＆INPIT

    Phenylephrine pharmaceutical formulation and composition for colonic absorption
    2.
    发明专利
    Phenylephrine pharmaceutical formulation and composition for colonic absorption 审中-公开
    苯并噻唑类药物制剂及其组合物

    公开(公告)号：JP2013006878A

    公开(公告)日：2013-01-10

    申请号：JP2012224253

    申请日：2012-10-09

    Applicant: Msd Consumer Care Inc ,  エムエスディー コンシューマー ケア, インコーポレイテッド

    Inventor： MONTEITH DAVID ,  O'MULLANE JOHN ,  REO JOSEPH P ,  NOWAK ROBERT T ,  WAN JIANSHENG ,  KABIR MOHAMMED A ,  ABUTARIF MALAZ A ,  FRITZ GLENN E

    IPC: A61K31/137 ,  A61K9/06 ,  A61K9/08 ,  A61K9/20 ,  A61K9/32 ,  A61K31/4545 ,  A61K45/00 ,  A61K47/12 ,  A61K47/18 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61P11/00 ,  A61P11/02 ,  A61P31/16

    CPC classification number: A61K31/137 ,  A61K9/167 ,  A61K9/2054 ,  A61K9/209 ,  A61K9/5026 ,  A61K9/5042 ,  A61K31/4545 ,  A61K47/12 ,  A61K47/38

    Abstract: PROBLEM TO BE SOLVED: To provide phenylephrine pharmaceutical formulations and compositions for colonic absorption.SOLUTION: The invention relates to a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration, wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layers. The pharmaceutical composition can further comprise one or more additional therapeutically active agents selected from one or more of the group consisting of antihistamines, analgesics, anti-pyretics, and non-steroidal anti-inflammatory agents.

    Abstract translation: 待解决的问题：提供苯肾上腺素药物制剂和用于结肠吸收的组合物。 解决方案：本发明涉及包含去氧肾上腺素或其药学上可接受的盐和用于口服给药的可溶性层的药物组合物，其中所述组合物通过在结肠中的吸收递送苯肾上腺素或其药学上可接受的盐。 药物组合物包含包含去氧肾上腺素或其药学上可接受的盐的核心和可溶性层，其处于时间依赖性，依赖于pH或结肠特异性的酶依赖性可溶解层，其降解以暴露核心以释放出去氧肾上腺素 结肠。 在一个优选实施例中，可侵蚀层包裹芯。 该组合物任选地还包含在可腐蚀层或其它附加层中的去氧肾上腺素。 药物组合物还可以包含一种或多种另外的治疗活性剂，其选自抗组胺剂，止痛剂，抗热解剂和非甾体抗炎剂中的一种或多种。 版权所有（C）2013，JPO＆INPIT

    Skin care composition
    4.
    发明专利
    Skin care composition 审中-公开
    皮肤护理组合物

    公开(公告)号：JP2013040216A

    公开(公告)日：2013-02-28

    申请号：JP2012259611

    申请日：2012-11-28

    Applicant: Msd Consumer Care Inc ,  エムエスディー コンシューマー ケア, インコーポレイテッド

    Inventor： FOWLER KEVIN C

    IPC: A61K8/88 ,  A01N25/00 ,  A61K8/04 ,  A61K8/06 ,  A61K8/34 ,  A61K8/84 ,  A61Q17/00 ,  A61Q17/02 ,  A61Q17/04 ,  A61Q19/00 ,  C08G69/44

    CPC classification number: A61Q17/00 ,  A61K8/06 ,  A61K8/88 ,  A61K2800/54 ,  A61Q17/02 ,  A61Q17/04

    Abstract: PROBLEM TO BE SOLVED: To provide a formulation showing an improved water resistance, having a physical characteristic that the moving of the formulation traversing the treated skin of a subject is reduced, providing a limited slip grip performance characteristic, and capable of protecting the skin from physical and biochemical effects of ultraviolet ray.SOLUTION: This is an emulsion formulation for topical application to the skin. The formulation contains an aqueous phase, an oil phase, at least a kind of emulsifier, and ethylenediamine/neopentyl glycol/stearyl hydrogenated dimer dilinoleate copolymer.

    Abstract translation: 要解决的问题：提供一种表现出改进的耐水性的配方，其具有使得穿过被处理皮肤的制剂的移动减小的物理特性，提供有限的滑动抓地性能特征，并且能够保护 皮肤从紫外线的物理和生物化学作用。

    解决方案：这是一种局部应用于皮肤的乳液制剂。 该制剂含有水相，油相，至少一种乳化剂，和乙二胺/新戊二醇/硬脂基氢化二聚体二烯丙酯共聚物。 版权所有（C）2013，JPO＆INPIT

    Enhanced photostability of suncare composition containing avobenzone
    6.
    发明专利
    Enhanced photostability of suncare composition containing avobenzone 审中-公开
    增强含有AVOBENZONE的组合物的光化学性能

    公开(公告)号：JP2013173798A

    公开(公告)日：2013-09-05

    申请号：JP2013120815

    申请日：2013-06-07

    Applicant: Msd Consumer Care Inc ,  エムエスディー コンシューマー ケア, インコーポレイテッド

    Inventor： MEYER THOMAS A ,  BEASLEY DONATHAN G

    IPC: A61K8/35 ,  A61K8/44 ,  A61Q17/04

    CPC classification number: A61Q17/04 ,  A61K8/35 ,  A61K8/411 ,  A61K2800/52

    Abstract: PROBLEM TO BE SOLVED: To provide compositions for skin application to protect against harmful effects of ultraviolet radiation, particularly the effects of solar radiation.SOLUTION: The photostability of avobenzone in sunscreen compositions is stabilized against photodegradation through the use of menthyl anthranilate. One example embodiment of the invention encompasses a composition including avobenzone and menthyl anthranilate, wherein the menthyl anthranilate is present in a sufficient amount to stabilize the avobenzone against photodegradation. Another example embodiment of the invention encompasses a method for protecting a skin against ultraviolet radiation, including a step of applying to the skin an effective amount of the composition comprising avobenzone and menthyl anthranilate, wherein the menthyl anthranilate is present in a sufficient amount to stabilize the avobenzone against photodegradation.

    Abstract translation: 要解决的问题：提供用于皮肤应用的组合物，以防止紫外线辐射的有害影响，特别是太阳辐射的影响。解决方案：防晒组合物中阿伏苯宗的光稳定性通过使用邻氨基苯甲酸酯来降解光降解。 本发明的一个示例性实施方案包括组合物，其包含阿伏苯宗和邻氨基苯甲酸薄荷酯，其中以足够的量存在苯甲酸薄荷酯以稳定阿伏苯宗以防光降解。 本发明的另一个示例性实施方案包括用于保护皮肤免受紫外线辐射的方法，包括向皮肤施用有效量的组合物的步骤，所述组合物包含阿伏苯宗和邻氨基苯甲酸薄荷酯，其中以相当的量存在足够的量的稳定 阿伏苯宗抗光降解。

    Device for mitigating odor in article of clothing or footwear
    7.
    发明专利
    Device for mitigating odor in article of clothing or footwear 审中-公开
    用于减轻衣服或鞋子的气味的装置

    公开(公告)号：JP2012179431A

    公开(公告)日：2012-09-20

    申请号：JP2012135876

    申请日：2012-06-15

    Applicant: Msd Consumer Care Inc ,  エムエスディー コンシューマー ケア, インコーポレイテッド

    Inventor： DEVER GERALD R ,  HOWLETT HAROLD A ,  YANG PHILIP C

    IPC: A43B17/00 ,  A43D3/00 ,  A61L9/01 ,  A61L9/04 ,  A61L9/12 ,  B65D85/00

    CPC classification number: A61L9/042 ,  A43D3/1491 ,  A61L9/12

    Abstract: PROBLEM TO BE SOLVED: To provide a deodorizer in particular, a deodorizer substrate with a porous carrier material formed in a monolithic form, and to provide an odor neutralizing composition in the porous carrier material.SOLUTION: There is disclosed an odor deodorizer. The odor deodorizer includes: a disk-shaped porous carrier material of microporous high density polyethylene, having pores in the range of 45-100 microns; an odor neutralizing composition of undecylenic acid and/or a derivative thereof in the porous carrier material; and a disk-shaped talc mixed, injection-moldable polypropylene housing sized to fit in a shoe and having a plurality of holes and containing the porous carrier, the housing being movable between an open to a closed configuration.

    Abstract translation: 要解决的问题：特别是提供除臭剂，具有形成为整体形式的多孔载体材料的除臭基材，并在多孔载体材料中提供气味中和组合物。 解决方案：公开了一种除臭臭味剂。 气味除臭剂包括：微孔高密度聚乙烯的圆盘形多孔载体材料，孔隙在45-100微米的范围内; 多孔载体材料中的十一碳烯酸和/或其衍生物的气味中和组合物; 以及圆盘状滑石混合的可注射成型聚丙烯壳体，其尺寸适于装配在鞋中并且具有多个孔并且容纳多孔载体，所述壳体可在打开至闭合构型之间移动。 版权所有（C）2012，JPO＆INPIT

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