公开(公告)号：PL2524221T3

公开(公告)日：2022-06-20

申请号：PL11733248

申请日：2011-01-11

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： CHAN LEO L ,  LI PETER

IPC: G01J3/10 ,  G01N21/64 ,  G01J3/44 ,  G01N15/14 ,  G01N21/17 ,  G01N33/50

公开(公告)号：US09186843B2

公开(公告)日：2015-11-17

申请号：US14587932

申请日：2014-12-31

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： Leo L. Chan ,  Jean Qiu

IPC: G01N1/10 ,  B29C59/02 ,  B01L3/00 ,  B29C65/50 ,  B29C65/00 ,  G01N15/14 ,  G01N21/64 ,  G01N21/03 ,  B29L31/00 ,  B29C65/48 ,  B29K33/00 ,  B29K63/00 ,  B29K75/00

CPC classification number: B29C59/021 ,  B01L3/502707 ,  B01L2200/0689 ,  B01L2300/0877 ,  B01L2300/0887 ,  B29C65/4825 ,  B29C65/4835 ,  B29C65/5021 ,  B29C65/5057 ,  B29C66/1122 ,  B29C66/53461 ,  B29C66/71 ,  B29K2033/08 ,  B29K2063/00 ,  B29K2075/00 ,  B29L2031/756 ,  G01N15/14 ,  G01N15/1463 ,  G01N15/1484 ,  G01N21/03 ,  G01N21/6458 ,  G01N2015/1486 ,  G01N2201/02 ,  Y10T29/49826 ,  B29K2067/00 ,  B29K2069/00 ,  B29K2033/12 ,  B29K2025/06 ,  B29K2023/38

Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.

公开(公告)号：DK2524221T3

公开(公告)日：2022-05-23

申请号：DK11733248

申请日：2011-01-11

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： CHAN LEO L ,  LI PETER

IPC: G01J3/10 ,  G01N21/64 ,  G01J3/44 ,  G01N15/14 ,  G01N21/17 ,  G01N33/50

公开(公告)号：WO2019165119A1

公开(公告)日：2019-08-29

申请号：PCT/US2019/019017

申请日：2019-02-21

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： LI, Peter, Y. ,  QIU, Jean ,  CHAN, Leo, L. ,  HASCUP, Justin, R. ,  SMITH, Timothy, F. ,  SOBOLEWSKI, Todd, R. ,  SHAW, Nicholas, N.

IPC: C12M1/00 ,  C12M3/00 ,  G01N1/10 ,  G01N33/483 ,  G01N35/00

Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc .

公开(公告)号：WO2016196567A1

公开(公告)日：2016-12-08

申请号：PCT/US2016/035178

申请日：2016-06-01

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： CHAN, Leo, L. ,  QIU, Jean ,  PETER, Li ,  DERY, Oliver ,  KESSEL, Sarah ,  SMITH, Timothy

IPC: G01N1/30 ,  C12Q1/02

CPC classification number: G01N1/30 ,  C12Q1/02 ,  G01N33/5005 ,  G01N33/52 ,  G01N2001/302

Abstract: The invention provides a method for accurate, efficient and high-throughout measurement of cell viability of diverse biological samples.

Abstract translation: 本发明提供了用于准确，有效和高度全面测量不同生物样品的细胞活力的方法。

公开(公告)号：US11911764B2

公开(公告)日：2024-02-27

申请号：US16963233

申请日：2019-02-21

Applicant: Nexcelom Bioscience LLC

Inventor： Peter Y. Li ,  Jean Qiu ,  Leo L. Chan ,  Justin R. Hascup ,  Timothy F. Smith ,  Todd R. Sobolewski ,  Nicholas N. Shaw

IPC: C12Q1/00 ,  B01L3/00 ,  G01N15/14 ,  G01N33/487 ,  G01N15/10

CPC classification number: B01L3/5085 ,  G01N15/147 ,  G01N33/4875 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/087 ,  B01L2300/0829 ,  G01N2015/1006 ,  G01N2015/1486

Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.

公开(公告)号：US20160025710A1

公开(公告)日：2016-01-28

申请号：US14790482

申请日：2015-07-02

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： Leo L. Chan ,  Jean Qiu ,  Peter Li ,  Kevin Flanagan ,  Timothy Smith

IPC: G01N33/50 ,  G01N21/64

CPC classification number: G01N33/5094 ,  G01N21/6428 ,  G01N21/6456 ,  G01N21/6486 ,  G06F19/26

Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.

公开(公告)号：US20180119195A1

公开(公告)日：2018-05-03

申请号：US15792572

申请日：2017-10-24

Applicant: Nexcelom Bioscience LLC

Inventor： Leo L. Chan ,  Jean Qiu ,  Peter Li ,  Kevin Flanagan

IPC: C12Q1/02 ,  G01N21/64

CPC classification number: C12Q1/02 ,  C12N1/16 ,  G01N15/1475 ,  G01N21/6428 ,  G01N21/6458 ,  G01N2015/0065 ,  G01N2015/0092 ,  G01N2015/1497 ,  G01N2021/6441 ,  G01N2333/395

Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.

公开(公告)号：US20150232906A1

公开(公告)日：2015-08-20

申请号：US14429878

申请日：2013-10-09

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： Leo L. Chan ,  Jean Qiu ,  Peter Li ,  Kevin Flanagan

IPC: C12Q1/02 ,  G01N21/64

CPC classification number: C12Q1/02 ,  C12N1/16 ,  G01N15/1475 ,  G01N21/6428 ,  G01N21/6458 ,  G01N2015/0065 ,  G01N2015/0092 ,  G01N2015/1497 ,  G01N2021/6441 ,  G01N2333/395

Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.

Abstract translation: 本发明一般涉及分析酵母存活率和酵母繁殖率。 更具体地，本发明涉及用于获取和测量酵母细胞的出芽百分比，活力和浓度的有效和有效的方法和组合物。

公开(公告)号：US20150183153A1

公开(公告)日：2015-07-02

申请号：US14587932

申请日：2014-12-31

Applicant: NEXCELOM BIOSCIENCE LLC

Inventor： Leo L. Chan ,  Jean Qiu

IPC: B29C59/02 ,  G01N15/14 ,  G01N21/03

CPC classification number: B29C59/021 ,  B01L3/502707 ,  B01L2200/0689 ,  B01L2300/0877 ,  B01L2300/0887 ,  B29C65/4825 ,  B29C65/4835 ,  B29C65/5021 ,  B29C65/5057 ,  B29C66/1122 ,  B29C66/53461 ,  B29C66/71 ,  B29K2033/08 ,  B29K2063/00 ,  B29K2075/00 ,  B29L2031/756 ,  G01N15/14 ,  G01N15/1463 ,  G01N15/1484 ,  G01N21/03 ,  G01N21/6458 ,  G01N2015/1486 ,  G01N2201/02 ,  Y10T29/49826 ,  B29K2067/00 ,  B29K2069/00 ,  B29K2033/12 ,  B29K2025/06 ,  B29K2023/38

Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.

Abstract translation: 本发明一般涉及用于分析和测量细胞和生物样品的分析和监测系统。 更具体地，本发明涉及一种独特的细胞计数室，例如用于细菌或寄生虫的亮场和荧光成像的薄间隙流体细胞室及其制备方法。