公开(公告)号：WO2011048472A1

公开(公告)日：2011-04-28

申请号：PCT/IB2010/002682

申请日：2010-10-20

Applicant: OR-EL ORGANSKA ELEKTRONIKA D.O.O. ,  MELPIGNANO, Patrizia

Inventor： MELPIGNANO, Patrizia

IPC: G01N21/64 ,  B01L3/00 ,  G01N21/05 ,  G01N21/03

CPC classification number: G01N33/54373 ,  B01L3/502715 ,  B01L2300/027 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0825 ,  B01L2300/0851 ,  G01N21/05 ,  G01N21/6454 ,  G01N21/6486 ,  G01N2021/0346 ,  G01N2021/056 ,  G01N2021/6439 ,  G01N2201/0628

Abstract: Device to detect at least an analyte, comprising a transparent substrate (2), having a first surface (3) with which a light source (7) is associated, and a second surface (4) on which a plurality of biological protein probes (12) are disposed, a layer (6) of polymer being interposed between said second surface (4) and said biological protein probes (12). A marker (fluorophore) is associated with said analyte, having determinate characteristics of fluorescence and/or phosphorescence correlated to the emission wavelength of the light source (7). Said light source (7) is suitable to emit a light radiation in a range of wavelengths equal to 400-550 nm, inside which range the absorption peak of said marker (fluorophore) used is comprised. The value of the distance ("s") between the wavelength corresponding to the absorption peak of the marker (fluorophore) and the wavelength corresponding to the emission peak of fluorescence (phosphorescence) is comprised between 25 and 150 nm.

Abstract translation: 用于检测至少一种分析物的装置，包括具有与光源（7）相关联的第一表面（3）的透明基底（2），以及第二表面（4），多个生物蛋白探针（ 12），聚合物层（6）插入在所述第二表面（4）和所述生物蛋白质探针（12）之间。 标记（荧光团）与所述分析物相关联，具有与光源（7）的发射波长相关的荧光和/或磷光的确定特性。 所述光源（7）适于发射在等于400-550nm的波长范围内的光辐射，其中包括所使用的所述标记（荧光团）的吸收峰。 对应于标记（荧光团）的吸收峰的波长与对应于荧光（磷光）的发射峰的波长之间的距离（“s”）的值为25-150nm。

公开(公告)号：EP2491371A1

公开(公告)日：2012-08-29

申请号：EP10785512.4

申请日：2010-10-20

Applicant: Or-El Organska Elektronika D.O.O.

Inventor： MELPIGNANO, Patrizia

IPC: G01N21/64 ,  B01L3/00 ,  G01N21/05 ,  G01N21/03

Abstract: Device to detect at least an analyte, comprising a transparent substrate (2), having a first surface (3) with which a light source (7) is associated, and a second surface (4) on which a plurality of biological protein probes (12) are disposed, a layer (6) of polymer being interposed between said second surface (4) and said biological protein probes (12). A marker (fluorophore) is associated with said analyte, having determinate characteristics of fluorescence and/or phosphorescence correlated to the emission wavelength of the light source (7). Said light source (7) is suitable to emit a light radiation in a range of wavelengths equal to 400-550 nm, inside which range the absorption peak of said marker (fluorophore) used is comprised. The value of the distance ("s") between the wavelength corresponding to the absorption peak of the marker (fluorophore) and the wavelength corresponding to the emission peak of fluorescence (phosphorescence) is comprised between 25 and 150 nm.

公开(公告)号：EP2491371B1

公开(公告)日：2020-03-11

申请号：EP10785512.4

申请日：2010-10-20

Applicant: Or-El Organska Elektronika D.O.O.

Inventor： MELPIGNANO, Patrizia

IPC: G01N21/64 ,  B01L3/00 ,  G01N21/05 ,  G01N21/03