公开(公告)号：WO2012049214A9

公开(公告)日：2012-04-19

申请号：PCT/EP2011/067823

申请日：2011-10-12

Applicant: F.HOFFMANN-LA ROCHE AG ,  ROCHE DIAGNOSTICS GMBH ,  NIERZWICK, Mark ,  PASH, Phillip, E. ,  TENBARGE, James, Duane

Inventor： NIERZWICK, Mark ,  PASH, Phillip, E. ,  TENBARGE, James, Duane

IPC: H04L29/06

Abstract: A diabetes care kit for providing diagnostics and therapy that is preconfigured to reduce initial setup by a user, comprising: a handheld diabetes managing device (104) including: a blood glucose meter (1041) configured to determine a blood glucose level of a user, a first processor (1043) coupled to the blood glucose meter (1041) and configured to generate an insulin pump command based on the blood glucose level, a first memory (1045) coupled to the processor (1043) and preloaded with an encryption key, a first communication module (1047) coupled to the processor and first memory (1045) and configured to generate an encrypted communication message based on the insulin pump command and the encryption key, and a first antenna (1049) coupled to the first communication module (1047) and configured to transmit the encrypted communication message; and an insulin pump (202; 204) including: an insulin dosing module (2041) configured to dispense insulin based on an insulin dose command, a second processor (2043) coupled to the insulin dosing module (2041) and configured to generate the insulin dose command based on the insulin pump command, a second memory (2045) coupled to the second processor (2043) and preloaded with the encryption key, a second communication module (2047) coupled to the second processor (2043) and the second memory (2045) and configured to decode the encrypted communication message based on the encryption key to obtain the insulin pump command, and a second antenna (2049) coupled to the second communication module (2047) and configured to receive the encrypted communication message, wherein the handheld diabetes managing device (104) and the insulin pump (202; 204) are paired such that a secure bidirectional communication link exists between the handheld diabetes managing device (104) and the insulin pump (202; 204).

公开(公告)号：WO2012084234A1

公开(公告)日：2012-06-28

申请号：PCT/EP2011/006484

申请日：2011-12-21

Applicant: ROCHE DIAGNOSTICS GMBH ,  F. HOFFMANN-LA ROCHE AG ,  ENGELHARDT, Timothy, Peter ,  NIERZWICK, Mark ,  PASH, Phillip, E. ,  HANDWERKER, Günter ,  FRISCH, Gerhard

Inventor： ENGELHARDT, Timothy, Peter ,  NIERZWICK, Mark ,  PASH, Phillip, E. ,  HANDWERKER, Günter ,  FRISCH, Gerhard

IPC: G06F19/00

CPC classification number: G16H40/40 ,  G06F19/00

Abstract: A method for storing data at a continuous glucose monitor is presented. The method includes measuring the blood glucose level of the patient. The method also includes receiving a plurality of physical attributes related to the glucose level of the patient. The method further includes determining calibration data based on the measured blood glucose level and at least one of the plurality of physical attribute samples, the calibration data configured to allow the handheld diabetes managing device to determine the estimated glucose level of the patient based on the plurality of physical attribute samples. Finally, the method includes transmitting the calibration data from the handheld diabetes managing device to the continuous glucose monitor for storage at the continuous glucose monitor. The calibration data and plurality of physical attribute samples can be retrieved by a separate device to determine an estimated glucose level of the patient.

Abstract translation: 提出了一种在连续葡萄糖监测器上存储数据的方法。 该方法包括测量患者的血糖水平。 该方法还包括接收与患者的葡萄糖水平相关的多个物理属性。 该方法还包括基于所测量的血糖水平和多个物理属性样本中的至少一个来确定校准数据，所述校准数据被配置为允许手持式糖尿病管理装置基于多个物理属性样本来确定患者的估计的葡萄糖水平 的物理属性样本。 最后，该方法包括将手持式糖尿病管理装置的校准数据传送到连续葡萄糖监测器，以便在连续葡萄糖监测器处储存。 校准数据和多个物理属性样本可以由单独的装置检索以确定患者的估计的葡萄糖水平。

公开(公告)号：WO2012049214A1

公开(公告)日：2012-04-19

申请号：PCT/EP2011/067823

申请日：2011-10-12

Applicant: F.HOFFMANN-LA ROCHE AG ,  ROCHE DIAGNOSTICS GMBH ,  NIERZWICK, Mark ,  PASH, Phillip, E. ,  TENBARGE, James, Duane

Inventor： NIERZWICK, Mark ,  PASH, Phillip, E. ,  TENBARGE, James, Duane

IPC: H04L29/06

CPC classification number: A61M5/1723 ,  G06F19/00 ,  G06F19/3468 ,  G16H40/63 ,  H04L63/061 ,  H04L63/0869 ,  H04W12/04 ,  H04W12/06

Abstract: A diabetes care kit for providing diagnostics and therapy that is preconfigured to reduce initial setup by a user, comprising: a handheld diabetes managing device (104) including: a blood glucose meter (1041) configured to determine a blood glucose level of a user, a first processor (1043) coupled to the blood glucose meter (1041) and configured to generate an insulin pump command based on the blood glucose level, a first memory (1045) coupled to the processor (1043) and preloaded with an encryption key, a first communication module (1047) coupled to the processor and first memory (1045) and configured to generate an encrypted communication message based on the insulin pump command and the encryption key, and a first antenna (1049) coupled to the first communication module (1047) and configured to transmit the encrypted communication message; and an insulin pump (202; 204) including: an insulin dosing module (2041) configured to dispense insulin based on an insulin dose command, a second processor (2043) coupled to the insulin dosing module (2041) and configured to generate the insulin dose command based on the insulin pump command, a second memory (2045) coupled to the second processor (2043) and preloaded with the encryption key, a second communication module (2047) coupled to the second processor (2043) and the second memory (2045) and configured to decode the encrypted communication message based on the encryption key to obtain the insulin pump command, and a second antenna (2049) coupled to the second communication module (2047) and configured to receive the encrypted communication message, wherein the handheld diabetes managing device (104) and the insulin pump (202; 204) are paired such that a secure bidirectional communication link exists between the handheld diabetes managing device (104) and the insulin pump (202; 204).

Abstract translation: 1。一种用于提供诊断和治疗的糖尿病护理套件，其预先配置为减少用户的初始设置，包括：手持式糖尿病管理设备（104），其包括：血糖仪（1041），其被配置为确定用户的血糖水平， 耦合到血糖仪（1041）并被配置为基于血糖水平生成胰岛素泵命令的第一处理器（1043），耦合到处理器（1043）并预加载加密密钥的第一存储器（1045） 耦合到处理器和第一存储器（1045）并被配置为基于胰岛素泵命令和加密密钥生成加密的通信消息的第一通信模块（1047），以及耦合到第一通信模块（1049）的第一天线（1049） 1047），并被配置为发送加密的通信消息; 和胰岛素泵（202; 204），所述胰岛素泵包括：被配置为基于胰岛素剂量指令分配胰岛素的胰岛素给药模块（2041），被连接到所述胰岛素给药模块（2041）并被配置成产生胰岛素的第二处理器 （2043）和预加载加密密钥的第二存储器（2045），与第二处理器（2043）和第二存储器（2043）耦合的第二通信模块（2047） 2045）并且被配置为基于所述加密密钥解码所述加密的通信消息以获得所述胰岛素泵命令;以及第二天线（2049），其耦合到所述第二通信模块（2047）并且被配置为接收所述加密的通信消息，其中所述手持设备 糖尿病管理装置（104）和胰岛素泵（202; 204）配对，使得手持式糖尿病管理装置（104）和胰岛素泵（202; 204）之间存在安全的双向通信链路。 204）。

公开(公告)号：WO2012048833A3

公开(公告)日：2012-04-19

申请号：PCT/EP2011/005035

申请日：2011-10-07

Applicant: ROCHE DIAGNOSTICS GMBH ,  F. HOFFMANN-LA ROCHE AG ,  BIRTWHISTLE, Daniel ,  LONG, James, R. ,  MARKISOHN, D., Bradley ,  NIERZWICK, Mark, Alan ,  PASH, Phillip, E. ,  REINKE, Robert, E. ,  SABO, Robert, P. ,  TENBARGE, James, D. ,  TIMMERMAN, Robert

Inventor： BIRTWHISTLE, Daniel ,  LONG, James, R. ,  MARKISOHN, D., Bradley ,  NIERZWICK, Mark, Alan ,  PASH, Phillip, E. ,  REINKE, Robert, E. ,  SABO, Robert, P. ,  TENBARGE, James, D. ,  TIMMERMAN, Robert

IPC: G06F19/00 ,  G06F11/14

Abstract: The present disclosure describes a handheld diabetes management device that implements a failsafe firmware upgrading protocol to reduce required user interaction and risk of device downtime. The general processing module executes first software from nonvolatile memory. The general processing module receives second software from an external port and writes the second software to the nonvolatile memory. Based on an upgrade signal, the general processing module switches execution from the first software to the second software, evaluates proper operation of the general processing module, and switches execution back to the first software from the second software when proper operation of the general processing module using the second software is not detected. A communications module, in electrical communication with the general processing module, stores third software and executes the third software. The general processing module receives fourth software from the external port and replaces the third software with the fourth software.

公开(公告)号：WO2012048833A2

公开(公告)日：2012-04-19

申请号：PCT/EP2011005035

申请日：2011-10-07

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  BIRTWHISTLE DANIEL ,  LONG JAMES R ,  MARKISOHN D BRADLEY ,  NIERZWICK MARK ALAN ,  PASH PHILLIP E ,  REINKE ROBERT E ,  SABO ROBERT P ,  TENBARGE JAMES D ,  TIMMERMAN ROBERT

Inventor： BIRTWHISTLE DANIEL ,  LONG JAMES R ,  MARKISOHN D BRADLEY ,  NIERZWICK MARK ALAN ,  PASH PHILLIP E ,  REINKE ROBERT E ,  SABO ROBERT P ,  TENBARGE JAMES D ,  TIMMERMAN ROBERT

IPC: G06F19/00

CPC classification number: G06F11/1433 ,  G06F11/1666 ,  G16H40/40

Abstract: The present disclosure describes a handheld diabetes management device that implements a failsafe firmware upgrading protocol to reduce required user interaction and risk of device downtime. The general processing module executes first software from nonvolatile memory. The general processing module receives second software from an external port and writes the second software to the nonvolatile memory. Based on an upgrade signal, the general processing module switches execution from the first software to the second software, evaluates proper operation of the general processing module, and switches execution back to the first software from the second software when proper operation of the general processing module using the second software is not detected. A communications module, in electrical communication with the general processing module, stores third software and executes the third software. The general processing module receives fourth software from the external port and replaces the third software with the fourth software.

Abstract translation: 本公开描述了实施故障安全固件升级协议以减少所需的用户交互和设备停机风险的手持式糖尿病管理设备。 通用处理模块从非易失性存储器执行第一软件。 通用处理模块从外部端口接收第二软件并将第二软件写入非易失性存储器。 基于升级信号，通用处理模块将执行从第一软件切换到第二软件，评估通用处理模块的正确操作，并且当通用处理模块正确操作时将执行从第二软件切换回第一软件 未检测到使用第二个软件。 与通用处理模块电通信的通信模块存储第三软件并执行第三软件。 通用处理模块从外部端口接收第四软件并用第四软件替换第三软件。

公开(公告)号：WO2012048831A3

公开(公告)日：2012-08-30

申请号：PCT/EP2011005033

申请日：2011-10-07

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  FRISCH GERHARD ,  IMHOF ERICH ,  REINKE ROBERT E ,  KONRAD GUIDO ,  LONG JAMES R ,  PASH PHILLIP E

Inventor： FRISCH GERHARD ,  IMHOF ERICH ,  REINKE ROBERT E ,  KONRAD GUIDO ,  LONG JAMES R ,  PASH PHILLIP E

IPC: G06F19/00

CPC classification number: G06F19/3418 ,  G06F19/3468 ,  G06Q50/22 ,  G16H10/60

Abstract: A diabetes management system having a reliable data management scheme is disclosed. The system comprises a plurality of devices, each device performing a different function relating to treatment of diabetes. Each device has a device identifier and each device generates data records relating to the function of the device. Each device includes a metadata generator configured to generate a metadata tag for a data record generated by the device. A metadata tag includes the device identifier of the corresponding device, a record identifier, and a source identifier indicating whether the record was originated by a human or the device. The system further includes a diabetes management device in communication with the plurality of devices and configured to manage records received from the plurality of devices. When a first device of the plurality of devices generates a new record to be communicated to the diabetes management device, the metadata generator of the first device generates a new unique record identifier and a new metadata tag based on the new unique record identifier and the device identifier of the first device, and the first device propagates the new record and the new metadata tag to the second device.

Abstract translation: 公开了具有可靠数据管理方案的糖尿病管理系统。 该系统包括多个装置，每个装置执行与治疗糖尿病有关的不同功能。 每个设备具有设备标识符，并且每个设备生成与设备的功能相关的数据记录。 每个设备包括元数据生成器，其被配置为生成由该设备生成的数据记录的元数据标签。 元数据标签包括相应设备的设备标识符，记录标识符和指示该记录是由人或设备发起的源标识符。 所述系统还包括与所述多个设备通信并被配置为管理从所述多个设备接收的记录的糖尿病管理设备。 当多个设备中的第一设备产生要传达到糖尿病管理设备的新记录时，第一设备的元数据生成器基于新的唯一记录标识符和设备生成新的唯一记录标识符和新的元数据标签 第一设备的标识符，并且第一设备将新记录和新的元数据标签传播到第二设备。

公开(公告)号：WO2012048831A8

公开(公告)日：2012-07-05

申请号：PCT/EP2011005033

申请日：2011-10-07

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  FRISCH GERHARD ,  IMHOF ERICH ,  REINKE ROBERT E ,  KONRAD GUIDO ,  LONG JAMES R ,  PASH PHILLIP E

Inventor： FRISCH GERHARD ,  IMHOF ERICH ,  REINKE ROBERT E ,  KONRAD GUIDO ,  LONG JAMES R ,  PASH PHILLIP E

IPC: G06F19/00

CPC classification number: G06F19/3418 ,  G06F19/3468 ,  G06Q50/22 ,  G16H10/60

Abstract: A diabetes management system having a reliable data management scheme is disclosed. The system comprises a plurality of devices, each device performing a different function relating to treatment of diabetes. Each device has a device identifier and each device generates data records relating to the function of the device. Each device includes a metadata generator configured to generate a metadata tag for a data record generated by the device. A metadata tag includes the device identifier of the corresponding device, a record identifier, and a source identifier indicating whether the record was originated by a human or the device. The system further includes a diabetes management device in communication with the plurality of devices and configured to manage records received from the plurality of devices. When a first device of the plurality of devices generates a new record to be communicated to the diabetes management device, the metadata generator of the first device generates a new unique record identifier and a new metadata tag based on the new unique record identifier and the device identifier of the first device, and the first device propagates the new record and the new metadata tag to the second device.

Abstract translation: 公开了具有可靠数据管理方案的糖尿病管理系统。 该系统包括多个装置，每个装置执行与糖尿病治疗有关的不同功能。 每个设备都有一个设备标识符，每个设备都会生成与设备功能相关的数据记录。 每个设备包括元数据生成器，其被配置为生成由设备生成的数据记录的元数据标签。 元数据标签包括对应设备的设备标识符，记录标识符以及指示记录是由人或设备发起的源标识符。 该系统还包括与多个设备通信并被配置为管理从多个设备接收的记录的糖尿病管理设备。 当多个设备中的第一设备生成要传送给糖尿病管理设备的新记录时，第一设备的元数据生成器基于新的唯一记录标识符和设备生成新的唯一记录标识符和新的元数据标签 第一设备的标识符，并且第一设备将新记录和新元数据标签传播到第二设备。

公开(公告)号：WO2012049224A1

公开(公告)日：2012-04-19

申请号：PCT/EP2011/067841

申请日：2011-10-12

Applicant: F.HOFFMANN-LA ROCHE AG ,  ROCHE DIAGNOSTICS GmbH ,  NIERZWICK, Mark ,  PASH, Phillip E. ,  TENBARGE, James Duane

Inventor： NIERZWICK, Mark ,  PASH, Phillip E. ,  TENBARGE, James Duane

IPC: G06F21/00 ,  H04L9/08 ,  H04L29/06

CPC classification number: H04W12/04 ,  A61B5/002 ,  A61B5/0024 ,  A61B5/14532 ,  G06F19/3468 ,  G16H20/17 ,  G16H40/63 ,  H04L9/0838 ,  H04L9/3242 ,  H04L63/061 ,  H04L63/0869 ,  H04L2209/805 ,  H04L2209/88 ,  H04W12/06

Abstract: The invention relates to a method for pairing a handheld diabetes managing device (104) with an insulin pump (204) for secure wireless communication with limited user interaction, comprising: at the insulin pump (204), outputting (408) a pump identification signal that contains a pump identification code that uniquely identifies the insulin pump (204); at the diabetes managing device (104), receiving (412) the pump identification signal; at the diabetes managing device (104), obtaining (414) the pump identification code from the pump identification signal; at the diabetes managing device (104), displaying (416) the pump identification code on a diabetes managing device display; at the insulin pump (204), displaying (418) the pump identification code on an insulin pump display; at the diabetes managing device (104), receiving (420) an insulin pump selection input that selects the pump identification code corresponding to the insulin pump; at the diabetes managing device (104), generating (428) a first verification string; at the insulin pump (204), generating (430) a second verification string; at the diabetes managing device (104), displaying (432) the first verification string on the diabetes managing device display; at the insulin pump (204), displaying (434) the second verification string on the insulin pump display; at the diabetes managing device (104), receiving (436) a first confirmation input corresponding to the first verification string matching the second verification string; at the insulin pump (204), receiving (438) a second confirmation input corresponding to the first verification string matching the second verification string; and establishing (440; 442) a secure bidirectional communication link between the diabetes managing device (104) and the insulin pump (204) based on the receipt of the first confirmation input by the diabetes managing device and the receipt of the second confirmation input by the insulin pump.

Abstract translation: 本发明涉及一种用于将手持式糖尿病管理装置（104）与胰岛素泵（204）配对以用于有限用户交互的安全无线通信的方法，包括：在胰岛素泵（204）处，输出（408）泵识别信号 其包含唯一地识别胰岛素泵（204）的泵识别码; 在糖尿病管理装置（104）处，接收（412）泵识别信号; 在所述糖尿病管理装置（104）处，从所述泵识别信号获取（414）所述泵识别码; 在糖尿病管理装置（104）上，在糖尿病管理装置显示器上显示（416）泵识别码; 在胰岛素泵（204）上，在胰岛素泵显示器上显示（418）泵标识码; 在所述糖尿病管理装置（104）处，接收（420）胰岛素泵选择输入，所述胰岛素泵选择输入选择对应于所述胰岛素泵的泵识别码; 在糖尿病管理装置（104）处，产生（428）第一验证串; 在所述胰岛素泵（204）处产生（430）第二验证串; 在糖尿病管理装置（104）上显示（432）第一验证串在糖尿病管理装置显示上; 在胰岛素泵（204）上，在胰岛素泵显示器上显示（434）第二验证串; 在所述糖尿病管理装置（104）处，接收对应于与所述第二验证串匹配的所述第一验证字符串的第一确认输入（436） 在所述胰岛素泵（204）处，接收与所述第二验证串匹配的所述第一验证串对应的第二确认输入（438） 以及基于糖尿病管理装置的第一确认输入的接收和第二确认输入的接收，建立（440; 442）在糖尿病管理装置（104）和胰岛素泵（204）之间的安全的双向通信链路 胰岛素泵。