中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

38 records (took 0.021 seconds)

    PRODUCTION OF STABLE CRYSTALLINE SODIUM ACETYLSALICYLATE
    1.
    发明申请
    PRODUCTION OF STABLE CRYSTALLINE SODIUM ACETYLSALICYLATE 审中-公开
    稳定的水溶性乙酸钠水溶液的生产

    公开(公告)号：WO1987005010A1

    公开(公告)日：1987-08-27

    申请号：PCT/US1987000376

    申请日：1987-02-20

    Applicant: PHARMACONTROL CORP.

    Inventor： PHARMACONTROL CORP. ,  DUCATMAN, Fred, P.

    IPC: C07C67/28

    CPC classification number: C07C67/28

    Abstract: A process for preparing sodium acetylsalicylate (sodium aspirin) in the form of plate-like crystals by preparing a solution of sodium aspirin, transferring the solution to a crystallizer, agitating the solution while cooling the crystallizer, intermittently adding seed crystals as crystallization progresses, separating the crystals from the mother liquor, and drying in a fluid bed dryer.

    Abstract translation: 通过制备钠阿司匹林溶液，将溶液转移到结晶器中，在冷却结晶器的同时搅拌溶液，随着晶体结晶进行间歇加入晶种，分离制备呈板状晶体形式的乙酰水杨酸钠（阿司匹林钠） 来自母液的晶体，并在流化床干燥器中干燥。

    STABLE SODIUM ASPIRIN TABLET COMPOSITIONS
    2.
    发明申请
    STABLE SODIUM ASPIRIN TABLET COMPOSITIONS 审中-公开
    稳定的阿司匹林片组合物

    公开(公告)号：WO1988007859A1

    公开(公告)日：1988-10-20

    申请号：PCT/US1987000849

    申请日：1987-04-13

    Applicant: PHARMACONTROL CORP.

    Inventor： PHARMACONTROL CORP. ,  DUCATMAN, Fred, P. ,  FLANAGAN, John, D.

    IPC: A61K31/60

    CPC classification number: A61K31/60 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018

    Abstract: Compositions are provided for the preparation of stable sodium aspirin tablets. The compositions comprise dry, crystalline sodium aspirin, an anhydrous binder that is unreactive to sodium aspirin and a hydrogenated animal or vegetable oil lubricant but lack the traditional tablet disintegrant. Tablets produced from these compositions can be stored for prolonged periods of time yet disintegrate in water at a rate comparable to that of ordinary aspirin.

    SAMPLING APPARATUS FOR OBTAINING A PLURALITY OF FLUID SAMPLES
    4.
    发明申请
    SAMPLING APPARATUS FOR OBTAINING A PLURALITY OF FLUID SAMPLES 审中-公开
    用于获得大量流体样品的采样设备

    公开(公告)号：WO1983003901A1

    公开(公告)日：1983-11-10

    申请号：PCT/US1983000599

    申请日：1983-04-22

    Applicant: PHARMACONTROL CORP.

    Inventor： PHARMACONTROL CORP. ,  COSGROVE, Robert, J., Jr. ,  SMOLEN, Victor, F.

    IPC: G01N31/00

    CPC classification number: G01N13/00 ,  G01N33/15 ,  G01N35/026 ,  G01N2013/006 ,  G01N2035/00198 ,  G01N2035/00752 ,  Y10S366/605

    Abstract: A sampling apparatus for obtaining a plurality of fluid samples particularly in connection with dissolution testing of various products. The apparatus includes a plurality of sampling containers (12) each having a chamber (26) therein for receipt of a fluid, and a drive device (60, 62, 64, 80) for simultaneously moving the plurality of sample containers to a sampling station. First fluid conduits (14) are provided for each of the sampling containers for conducting a fluid into each of the sampling containers when the sampling containers are positioned at the sampling station, and second fluid conduits (16) are provided for each of the sampling containers for withdrawing a sample fluid from each of the sampling containers when the sampling containers are positioned at the sampling station. Devices (82, 84) are provided for coupling the first and second fluid conduits with the chambers of each of the sampling containers when the sampling containers are positioned at the sampling station, such devices in addition being adapted to individually seal the chambers of each of the sampling chambers when the first and second fluid conduits are coupled thereto. In the preferred embodiment, each of the sampling containers also includes an agitation element (28) for agitating fluid introduced into the containers at the sampling station.

    APPARATUS FOR USE IN SPECTROSCOPICALLY ANALYZING PROPERTIES OF TEST SAMPLES
    5.
    发明申请
    APPARATUS FOR USE IN SPECTROSCOPICALLY ANALYZING PROPERTIES OF TEST SAMPLES 审中-公开
    用于测试样品的光谱分析特性的装置

    公开(公告)号：WO1983003900A1

    公开(公告)日：1983-11-10

    申请号：PCT/US1983000600

    申请日：1983-04-22

    Applicant: PHARMACONTROL CORP.

    Inventor： PHARMACONTROL CORP. ,  COSGROVE, Robert, J., Jr. ,  SMOLEN, Victor, F.

    IPC: G01N21/01

    CPC classification number: G01N21/253 ,  G01N2201/0423

    Abstract: An apparatus (10) for use in spectroscopically analyzing properties of a plurality of test samples. The apparatus includes a support member (12) for stationarily supporting a plurality of test cells (14) containing test samples (16) to be analyzed and suitable devices for directing a beam of radiation successively at the test cells (14) and for then receiving output radiation from the test cells. The radiation directly (20) and detector devices (30) are mounted in fixed relationship to one another, and arranged with respect to the support member (12) so that when the beam of radiation from the radiation directing device (20) is directed onto one of the test cells (14), the radiation detector (30) will receive output radiation from the same cell. The radiation directing (20) and detector devices (30) are moved as a unit relative to the stationary test cells (14) in a manner so that the beam of radiation from the directing device (20) is directed sucessively at the plurality of test cells (14), whereby the radiation detector device (30) will then receive successively output radiation from the plrality of test cells (14). In this manner, analysis of the properties of a plurality of test samples may be quickly and efficiently made. Further, the fact that the test cells (14) are stationarily supported and the radiation directing (20) and detecting devices (30) are moved relative thereto is most advantageous in connection with spectroscopic analysis of flow through fluid test samples in which the sample fluid to be analyzed is continuously introduced into and withdrawn (17a, 17b) from the stationarily supported test cells.

    Abstract translation: 一种用于光谱分析多个测试样品的性质的设备（10）。 该装置包括用于固定地支撑包含要分析的测试样本（16）的多个测试单元（14）的支撑构件（12），以及用于在测试单元（14）处连续地引导辐射束的适当装置，然后接收 输出来自测试单元的辐射。 直接辐射（20）和检测器装置（30）以固定关系彼此安装并相对于支撑构件（12）布置，使得当来自辐射导向装置（20）的辐射束被引导到 测试单元（14）中的一个，辐射检测器（30）将接收来自相同单元的输出辐射。 辐射导向（20）和检测器装置（30）以相对于固定测试电池（14）的单位移动，使得来自引导装置（20）的辐射束在多次测试 单元（14），由此辐射检测器装置（30）将随后从测试单元（14）的一致性接收输出的辐射。 以这种方式，可以快速有效地对多个测试样品的性质进行分析。 此外，测试电池（14）固定支撑并且辐射导向（20）和检测装置（30）相对于其移动的事实与通过流体测试样品的流体的光谱分析相关是最有利的，其中样品流体 被分析的物品从固定支撑的测试单元连续地引入和从中抽出（17a，17b）。

    Stable sodium aspirin tablet compositions
    10.
    发明公开
    Stable sodium aspirin tablet compositions 失效
    稳定的阿司匹林片组合物

    公开(公告)号：EP0213761A3

    公开(公告)日：1988-10-05

    申请号：EP86305927

    申请日：1986-08-01

    Applicant: PHARMACONTROL CORP.

    Inventor： Ducatman, Fred P. ,  Flanagan, John D.

    IPC: A61K31/60 ,  A61K09/20

    CPC classification number: A61K31/60 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018

    Abstract: Compositions are provided for the preparation of stable sodium aspirin tablets. The compositions comprise dry, crystalline sodium aspirin, an anhydrous binder that is unreactive to sodium aspirin and a hydrogenated animal or vegetable oil lubricant but lack the traditional tablet disintegrant. Tablets produced from these compositions can be stored for prolonged periods of time yet disintegrate in water at a rate comparable to that of ordinary aspirin.

Patent Agency Ranking