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公开(公告)号:WO2006083833A3
公开(公告)日:2007-02-22
申请号:PCT/US2006003354
申请日:2006-01-31
Applicant: HARVARD COLLEGE , WEIBEL DOUGLAS B , LEE ANDREW , POTENTA SCOTT , SIEGEL ADAM , KRUITHOF MAARTEN , WHITESIDES GEORGE M
Inventor: WEIBEL DOUGLAS B , LEE ANDREW , POTENTA SCOTT , SIEGEL ADAM , KRUITHOF MAARTEN , WHITESIDES GEORGE M
IPC: F16K3/24
CPC classification number: F15B1/04 , B01L3/502738 , B01L3/502746 , B01L2200/0636 , B01L2300/0867 , B01L2400/0487 , B01L2400/0655 , B01L2400/082 , F15B2201/21 , F15B2201/305 , F15B2201/4053 , F16K99/0001 , F16K99/0026 , F16K99/0034 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084 , Y10T137/0318 , Y10T137/0396 , Y10T137/2213 , Y10T137/4824 , Y10T137/6161
Abstract: A microfluidic valve assembly includes a structure defining a microfluidic fluid path and an actuator that can be moved between different positions controlling flow through the channel. In one embodiment, the actuator can be threaded into at least a portion of the structure, and can be moved rotationally between a first position, causing relatively greater constriction of a microfluidic fluid path, and a second position causing relatively lesser constriction of the fluid path. Actuating the actuator, e.g., by rotation, can deform material between the valve and the fluid path, thereby constricting at least a portion of the underlying fluid path and regulating the flow of a fluid in the fluid path. In another aspect, the invention provides a reservoir into which fluid can be placed and from which fluid can be introduced into a microfluidic system. In one embodiment, the reservoir is expandable and thereby able to store fluid under pressure for delivery to a microfluidic system.
Abstract translation: 微流体阀组件包括限定微流体流体路径的结构和可以在控制流过通道的不同位置之间移动的致动器。 在一个实施例中,致动器可以被螺纹连接到结构的至少一部分中,并且可以在第一位置和第二位置之间旋转地移动,第一位置引起微流体流体路径的相对较大的收缩,并且引起相对较小的流体路径收缩的第二位置 。 例如通过旋转来致动致动器可以在阀和流体路径之间变形材料,从而收缩下面的流体路径的至少一部分并且调节流体路径中的流体的流动。 在另一方面,本发明提供了一种储存器,流体可以放置在该储存器中,并且可以从该储存器将流体引入到微流体系统中。 在一个实施例中,储存器是可膨胀的并且因此能够在压力下存储流体以递送到微流体系统。
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公开(公告)号:WO2006083833A2
公开(公告)日:2006-08-10
申请号:PCT/US2006/003354
申请日:2006-01-31
Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE , WEIBEL, Douglas, B. , LEE, Andrew , POTENTA, Scott , SIEGEL, Adam , KRUITHOF, Maarten , WHITESIDES, George, M.
Inventor: WEIBEL, Douglas, B. , LEE, Andrew , POTENTA, Scott , SIEGEL, Adam , KRUITHOF, Maarten , WHITESIDES, George, M.
IPC: F16K3/24
CPC classification number: F15B1/04 , B01L3/502738 , B01L3/502746 , B01L2200/0636 , B01L2300/0867 , B01L2400/0487 , B01L2400/0655 , B01L2400/082 , F15B2201/21 , F15B2201/305 , F15B2201/4053 , F16K99/0001 , F16K99/0026 , F16K99/0034 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084 , Y10T137/0318 , Y10T137/0396 , Y10T137/2213 , Y10T137/4824 , Y10T137/6161
Abstract: A microfluidic valve assembly includes a structure defining a microfluidic fluid path and an actuator that can be moved between different positions controlling flow through the channel. In one embodiment, the actuator can be threaded into at least a portion of the structure, and can be moved rotationally between a first position, causing relatively greater constriction of a microfluidic fluid path, and a second position causing relatively lesser constriction of the fluid path. Actuating the actuator, e.g., by rotation, can deform material between the valve and the fluid path, thereby constricting at least a portion of the underlying fluid path and regulating the flow of a fluid in the fluid path. In another aspect, the invention provides a reservoir into which fluid can be placed and from which fluid can be introduced into a microfluidic system. In one embodiment, the reservoir is expandable and thereby able to store fluid under pressure for delivery to a microfluidic system.
Abstract translation: 微流体阀组件包括限定微流体流体路径的结构和可以在控制流过通道的不同位置之间移动的致动器。 在一个实施例中,致动器可以被螺纹连接到结构的至少一部分中,并且可以在第一位置和第二位置之间旋转地移动,第一位置引起微流体流体路径的相对较大的收缩,并且引起相对较小的流体路径收缩的第二位置 。 例如通过旋转来致动致动器可以在阀和流体路径之间变形材料,从而收缩下面的流体路径的至少一部分并且调节流体路径中的流体的流动。 在另一方面,本发明提供了一种储存器,流体可以放置在该储存器中,并且可以从该储存器将流体引入到微流体系统中。 在一个实施例中,储存器是可膨胀的并且因此能够在压力下存储流体以递送到微流体系统。
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