公开(公告)号：WO2009009665A2

公开(公告)日：2009-01-15

申请号：PCT/US2008069653

申请日：2008-07-10

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  DEVARAKONDA SURYA NARAYANA ,  YARRAGUNTLA SESHA REDDY ,  NALIVELA VENU ,  THAIMATTAM RAM ,  PEDDIREDDY SUBBAREDDY ,  RAGHUPATI BALAJI ,  BAIG MOHAMMED AZEEZULLA ,  GADE SRINIVAS REDDY ,  MALLEPALLI SRINIVAS REDDY ,  CHITTA VIJAYWARDHAN ,  BOLLIKONDA SATYANARAYANA ,  MOHANARANGAM SARAVANAN ,  KADABOINA RAJASEKHAR

Inventor： DEVARAKONDA SURYA NARAYANA ,  YARRAGUNTLA SESHA REDDY ,  NALIVELA VENU ,  THAIMATTAM RAM ,  PEDDIREDDY SUBBAREDDY ,  RAGHUPATI BALAJI ,  BAIG MOHAMMED AZEEZULLA ,  GADE SRINIVAS REDDY ,  MALLEPALLI SRINIVAS REDDY ,  CHITTA VIJAYWARDHAN ,  BOLLIKONDA SATYANARAYANA ,  MOHANARANGAM SARAVANAN ,  KADABOINA RAJASEKHAR

IPC: A61K31/135 ,  A61K9/22

CPC classification number: A61K31/135 ,  A61K9/146

Abstract: Processes for preparing desvenlafaxine and stable amorphous O-desmethylvenlafaxine succinate solid dispersions with one or more pharmaceutically acceptable carriers.

Abstract translation: 用一种或多种药学上可接受的载体制备Desvenlafaxine和稳定的无定形O-去甲基文拉法辛琥珀酸酯固体分散体的方法。

公开(公告)号：WO2010028105A2

公开(公告)日：2010-03-11

申请号：PCT/US2009/055815

申请日：2009-09-03

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  KADABOINA, Rajasekhar ,  NARIYAM, Sekhar Munaswamy ,  RAMAKRISHNAN, Srividya ,  PEDDIREDDY, Subbareddy ,  BAIG, Mohammed, Azeezulla ,  DUGGIRALA, Nagakiran

Inventor： KADABOINA, Rajasekhar ,  NARIYAM, Sekhar Munaswamy ,  RAMAKRISHNAN, Srividya ,  PEDDIREDDY, Subbareddy ,  BAIG, Mohammed, Azeezulla ,  DUGGIRALA, Nagakiran

IPC: C07D487/04 ,  C07F1/04

CPC classification number: C07D487/04

Abstract: Processes for the preparation of amorphous pemetrexed disodium, and removal of residual solvents from amorphous pemetrexed disodium.

Abstract translation: 制备无定形培美曲塞二钠的方法和从无定形培美曲塞二钠中除去残余溶剂的方法。

公开(公告)号：WO2007112457A2

公开(公告)日：2007-10-04

申请号：PCT/US2007/065474

申请日：2007-03-29

Applicant: DR. REDDY'S LABORTORIES, LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  MATHAD, Vijayavitthal, Thippannachar ,  VANKAWALA, Pravinchandra, Jayantilal ,  ELATI, Raviram, Chandrasekhar ,  MACHARLA, Prabhakar ,  GANGULA, Srinivas ,  KOLLA, Naveen, Kumar ,  KOMAREDDY, Ravi, Kumar ,  DEVARKONDA, Surya, Narayana ,  PEDDIREDDY, Subbareddy

Inventor： MATHAD, Vijayavitthal, Thippannachar ,  VANKAWALA, Pravinchandra, Jayantilal ,  ELATI, Raviram, Chandrasekhar ,  MACHARLA, Prabhakar ,  GANGULA, Srinivas ,  KOLLA, Naveen, Kumar ,  KOMAREDDY, Ravi, Kumar ,  DEVARKONDA, Surya, Narayana ,  PEDDIREDDY, Subbareddy

IPC: A61K31/5377

CPC classification number: C07D413/06

Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.

Abstract translation: 形式I和结晶形式II的紧密混合物，具有比例的形式。

公开(公告)号：WO2010028105A3

公开(公告)日：2010-06-10

申请号：PCT/US2009055815

申请日：2009-09-03

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  KADABOINA RAJASEKHAR ,  NARIYAM SEKHAR MUNASWAMY ,  RAMAKRISHNAN SRIVIDYA ,  PEDDIREDDY SUBBAREDDY ,  BAIG MOHAMMED AZEEZULLA ,  DUGGIRALA NAGAKIRAN

Inventor： KADABOINA RAJASEKHAR ,  NARIYAM SEKHAR MUNASWAMY ,  RAMAKRISHNAN SRIVIDYA ,  PEDDIREDDY SUBBAREDDY ,  BAIG MOHAMMED AZEEZULLA ,  DUGGIRALA NAGAKIRAN

IPC: C07D487/04 ,  C07F1/04

CPC classification number: C07D487/04

Abstract: Processes for the preparation of amorphous pemetrexed disodium, and removal of residual solvents from amorphous pemetrexed disodium.

Abstract translation: 制备无定形培美曲塞二钠的方法，并从无定形培美曲塞二钠中除去残留溶剂。

公开(公告)号：WO2009009665A3

公开(公告)日：2009-01-15

申请号：PCT/US2008/069653

申请日：2008-07-10

Applicant: DR. REDDY'S LABORATORIES, LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  DEVARAKONDA, Surya Narayana ,  YARRAGUNTLA, Sesha Reddy ,  NALIVELA, Venu ,  THAIMATTAM, Ram ,  PEDDIREDDY, Subbareddy ,  RAGHUPATI, Balaji ,  BAIG, Mohammed Azeezulla ,  GADE, Srinivas Reddy ,  MALLEPALLI, Srinivas Reddy ,  CHITTA, Vijaywardhan ,  BOLLIKONDA, Satyanarayana ,  MOHANARANGAM, Saravanan ,  KADABOINA, Rajasekhar

Inventor： DEVARAKONDA, Surya Narayana ,  YARRAGUNTLA, Sesha Reddy ,  NALIVELA, Venu ,  THAIMATTAM, Ram ,  PEDDIREDDY, Subbareddy ,  RAGHUPATI, Balaji ,  BAIG, Mohammed Azeezulla ,  GADE, Srinivas Reddy ,  MALLEPALLI, Srinivas Reddy ,  CHITTA, Vijaywardhan ,  BOLLIKONDA, Satyanarayana ,  MOHANARANGAM, Saravanan ,  KADABOINA, Rajasekhar

IPC: A61K31/135 ,  A61K9/22 ,  C07C217/74

Abstract: Processes for preparing desvenlafaxine and stable amorphous O-desmethylvenlafaxine succinate solid dispersions with one or more pharmaceutically acceptable carriers.

公开(公告)号：US09212172B2

公开(公告)日：2015-12-15

申请号：US13822519

申请日：2011-09-14

Applicant: Sundra Lakshmi Kanniah ,  Rajesham Boge ,  Peddireddy Subbareddy ,  Lalita Kanwar ,  Srividya Ramakrishnan ,  Ramya Kumar ,  Rakeshwar Bandichhor ,  Amarnath Reddy Lekkala ,  Ravi Kumar Mylavarapu ,  Vagwala Raghunath

Inventor： Sundra Lakshmi Kanniah ,  Rajesham Boge ,  Peddireddy Subbareddy ,  Lalita Kanwar ,  Srividya Ramakrishnan ,  Ramya Kumar ,  Rakeshwar Bandichhor ,  Amarnath Reddy Lekkala ,  Ravi Kumar Mylavarapu ,  Vagwala Raghunath

IPC: C07D403/10 ,  C07D403/12 ,  C07D209/12

CPC classification number: C07D403/12 ,  C07D209/12

Abstract: Aspects of the present disclosure include crystalline bazedoxifene free base, crystalline bazedoxifene acetate Form D, and processes for their preparation. The drug compound having the adopted name “bazedoxifene acetate” has a chemical name 1-[4-(2-azepan-1-yl-ethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetic acid, and has the chemical structure shown below as Formula I.

Abstract translation: 本公开内容的方面包括结晶巴西多昔芬游离碱，结晶乙酸巴多昔芬乙酸酯形式D及其制备方法。 具有采用的名称为“醋酸巴多昔芬”的药物化合物具有化学名称1- [4-（2-氮杂环庚烷-1-基 - 乙氧基）苄基] -2-（4-羟基苯基）-3-甲基-1H-吲哚-2-基） 5-醇乙酸，具有如下式I所示的化学结构。

公开(公告)号：US20130225805A1

公开(公告)日：2013-08-29

申请号：US13822519

申请日：2011-09-14

Applicant: Sundra Lakshmi Kanniah ,  Rajesham Boge ,  Peddireddy Subbareddy ,  Lalita Kanwar ,  Srividya Ramakrishnan ,  Ramya Kumar ,  Rakeshwar Bandichhor ,  Amarnath Reddy Lekkala ,  Ravi Kumar Mylavarapu ,  Vagwala Raghunath

Inventor： Sundra Lakshmi Kanniah ,  Rajesham Boge ,  Peddireddy Subbareddy ,  Lalita Kanwar ,  Srividya Ramakrishnan ,  Ramya Kumar ,  Rakeshwar Bandichhor ,  Amarnath Reddy Lekkala ,  Ravi Kumar Mylavarapu ,  Vagwala Raghunath

IPC: C07D403/12

CPC classification number: C07D403/12 ,  C07D209/12

Abstract: Aspects of the present disclosure include crystalline bazedoxifene free base, crystalline bazedoxifene acetate Form D, and processes for their preparation. The drug compound having the adopted name “bazedoxifene acetate” has a chemical name 1-[4-(2-azepan-1-yl-ethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetic acid, and has the chemical structure shown below as Formula I.

Abstract translation: 本公开内容的方面包括结晶巴西多昔芬游离碱，结晶乙酸巴多昔芬乙酸酯形式D及其制备方法。 具有采用的名称为“醋酸巴多昔芬”的药物化合物具有化学名称1- [4-（2-氮杂环庚烷-1-基 - 乙氧基）苄基] -2-（4-羟基苯基）-3-甲基-1H-吲哚-2-基） 5-醇乙酸，其化学结构如式I所示。

公开(公告)号：WO2009117489A1

公开(公告)日：2009-09-24

申请号：PCT/US2009/037516

申请日：2009-03-18

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  KOLLA, Naveen, Kumar ,  MANNE, Nagaraju ,  GANGULA, Srinivas ,  NEELAM, Udaykumar ,  NAREDLA, Anitha ,  BADDAM, Sudhakar, Reddy ,  PATIL, Sumeet, Vishwasrao ,  TUMMALA, Arjunkumar ,  PEDDIREDDY, Subbareddy ,  SHINDE, Sachin, Gulabrao ,  SIGALA, Ashok ,  MUDUNURU, Satish Varma ,  TUMMIDI, Madhu, Kiran

Inventor： KOLLA, Naveen, Kumar ,  MANNE, Nagaraju ,  GANGULA, Srinivas ,  NEELAM, Udaykumar ,  NAREDLA, Anitha ,  BADDAM, Sudhakar, Reddy ,  PATIL, Sumeet, Vishwasrao ,  TUMMALA, Arjunkumar ,  PEDDIREDDY, Subbareddy ,  SHINDE, Sachin, Gulabrao ,  SIGALA, Ashok ,  MUDUNURU, Satish Varma ,  TUMMIDI, Madhu, Kiran

IPC: C07D403/12 ,  C07D235/28 ,  C07D235/24

CPC classification number: C07D401/12 ,  A61K9/1635 ,  A61K9/1652 ,  A61K47/6951 ,  B82Y5/00

Abstract: Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.

Abstract translation: 右兰索拉唑，无效形式的右兰索拉唑，无定形右兰索拉唑的固体分散体和药学上可接受的载体的方法及其制备方法。 还提供了结晶化合物2 - [（R） - [（4-氯-3-甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑和2 - [（R） - [（4-硝基-3- 甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑及其制备方法。

公开(公告)号：WO2007112457A3

公开(公告)日：2008-10-09

申请号：PCT/US2007065474

申请日：2007-03-29

Applicant: REDDY S LABORTORIES LTD DR ,  REDDYS LAB INC DR ,  MATHAD VIJAYAVITTHAL THIPPANNACHAR ,  VANKAWALA PRAVINCHANDRA JAYANTILAL ,  ELATI RAVIRAM CHANDRASEKHAR ,  MACHARLA PRABHAKAR ,  GANGULA SRINIVAS ,  KOLLA NAVEEN KUMAR ,  KOMAREDDY RAVI KUMAR ,  DEVARKONDA SURYA NARAYANA ,  PEDDIREDDY SUBBAREDDY

Inventor： MATHAD VIJAYAVITTHAL THIPPANNACHAR ,  VANKAWALA PRAVINCHANDRA JAYANTILAL ,  ELATI RAVIRAM CHANDRASEKHAR ,  MACHARLA PRABHAKAR ,  GANGULA SRINIVAS ,  KOLLA NAVEEN KUMAR ,  KOMAREDDY RAVI KUMAR ,  DEVARKONDA SURYA NARAYANA ,  PEDDIREDDY SUBBAREDDY

IPC: A61K31/5377 ,  C07D413/06

CPC classification number: C07D413/06

Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.

Abstract translation: 形式I和结晶形式II的紧密混合物，具有比例的形式。