公开(公告)号：WO2012061451A2

公开(公告)日：2012-05-10

申请号：PCT/US2011/058881

申请日：2011-11-02

Applicant: POCARED DIAGNOSTICS INC. ,  INGBER, Gal

Inventor： INGBER, Gal

IPC: C12M1/34 ,  C12M1/24 ,  C12M1/18 ,  C12Q1/04

CPC classification number: G01N21/0303 ,  B01L3/508 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/028 ,  B01L2200/12 ,  B01L2300/0809 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/168 ,  C12M41/36 ,  G01N21/6452 ,  G01N35/025 ,  G01N2021/0321 ,  G01N2021/0382 ,  G01N2021/6469 ,  G01N2021/6482 ,  G01N2035/00346 ,  G01N2035/0429 ,  G01N2035/0449

Abstract: The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

Abstract translation: 本发明涉及一种用于对微生物（例如生物样品中的细菌）进行鉴定和定量的系统。 更具体地说，本发明涉及一种包括一次性盒和具有锥形表面的光学杯或比色皿的系统; 其中所述壁成角度以允许更好的涂层和更好的光线条纹，光学系统包括光学读取器和热控制器; 光学分析仪; 一个冷却系统; 和一个改进的光谱仪。 该系统可以使用样品处理器中的一次性盒和光学分析仪中的光学杯或比色皿。

公开(公告)号：WO2012061451A3

公开(公告)日：2012-06-28

申请号：PCT/US2011058881

申请日：2011-11-02

Applicant: POCARED DIAGNOSTICS INC ,  INGBER GAL

Inventor： INGBER GAL

IPC: C12M1/34 ,  C12M1/18 ,  C12M1/24 ,  C12Q1/04

CPC classification number: G01N21/0303 ,  B01L3/508 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/028 ,  B01L2200/12 ,  B01L2300/0809 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/168 ,  C12M41/36 ,  G01N21/6452 ,  G01N35/025 ,  G01N2021/0321 ,  G01N2021/0382 ,  G01N2021/6469 ,  G01N2021/6482 ,  G01N2035/00346 ,  G01N2035/0429 ,  G01N2035/0449

Abstract: The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

Abstract translation: 本发明涉及用于进行微生物（例如生物样品中的细菌）的鉴定和定量的系统。 更具体地，本发明涉及一种包括一次性盒和具有锥形表面的光学杯或比色杯的系统; 其中所述壁成角度以允许所述光的更好的涂覆和更好的条纹，包括光学读取器和热控制器的光学系统; 光学分析仪; 冷却系统; 和改进的光谱仪。 该系统可以利用样品处理器中的一次性盒，以及光学分析仪中的光学杯或反应杯。

公开(公告)号：WO2012103174A2

公开(公告)日：2012-08-02

申请号：PCT/US2012022488

申请日：2012-01-25

Applicant: POCARED DIAGNOSTICS INC ,  INGBER GAL

Inventor： INGBER GAL

IPC: C12M1/34 ,  C12M1/12 ,  C12M1/42 ,  C12Q1/04

CPC classification number: G01N21/07 ,  G01N21/31 ,  G01N2201/063

Abstract: A system and a method for optimizing an iris setting, used in combination with a lamp, for each excitation wavelength for each carousel run in an apparatus for identifying and measuring bacteria in biological samples. The system includes a feedback control loop positioned between a filter wheel and an optical cup for measuring the intensity level of the excitation wavelength, and feeding this information to an iris having an iris setting control device such that the iris setting may be adjusted based upon the measured intensity level to control and optimize the level of light fed to the filter wheel from the lamp. The iris setting can be adjusted so that the level of light fed to the filter wheel remains constant during the lifetime of the lamp and to ensure that the level of light fed to the sample remains below the level at which photo-bleaching occurs.

Abstract translation: 用于在用于识别和测量生物样品中的细菌的装置中运行的每个转盘的每个激发波长优化与灯组合使用的虹膜设置的系统和方法。 该系统包括位于滤光轮和光学杯之间的反馈控制回路，用于测量激发波长的强度水平，并将该信息馈送到具有光圈设置控制装置的光圈，使得可以基于 测量强度水平以控制和优化从灯进入滤光轮的光的水平。 可以调节光圈设置，使得在灯的寿命期间馈送到滤光轮的光的水平保持恒定，并且确保馈送到样品的光的水平保持低于发生光漂白的水平。

公开(公告)号：WO2012103174A3

公开(公告)日：2012-08-02

申请号：PCT/US2012/022488

申请日：2012-01-25

Applicant: POCARED DIAGNOSTICS INC. ,  INGBER, Gal

Inventor： INGBER, Gal

IPC: C12M1/34 ,  C12M1/42 ,  C12M1/12 ,  C12Q1/04

Abstract: A system and a method for optimizing an iris setting, used in combination with a lamp, for each excitation wavelength for each carousel run in an apparatus for identifying and measuring bacteria in biological samples. The system includes a feedback control loop positioned between a filter wheel and an optical cup for measuring the intensity level of the excitation wavelength, and feeding this information to an iris having an iris setting control device such that the iris setting may be adjusted based upon the measured intensity level to control and optimize the level of light fed to the filter wheel from the lamp. The iris setting can be adjusted so that the level of light fed to the filter wheel remains constant during the lifetime of the lamp and to ensure that the level of light fed to the sample remains below the level at which photo-bleaching occurs.

公开(公告)号：CA2853976A1

公开(公告)日：2012-05-10

申请号：CA2853976

申请日：2011-11-02

Applicant: POCARED DIAGNOSTICS INC

Inventor： INGBER GAL

IPC: C12M1/34 ,  C12M1/18 ,  C12M1/24 ,  C12Q1/04

Abstract: The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

公开(公告)号：EP2668257A2

公开(公告)日：2013-12-04

申请号：EP12739232.2

申请日：2012-01-25

Applicant: Pocared Diagnostics Inc.

Inventor： INGBER, Gal

IPC: C12M1/34 ,  C12M1/42 ,  C12M1/12 ,  C12Q1/04

CPC classification number: G01N21/07 ,  G01N21/31 ,  G01N2201/063

Abstract: A system and a method for optimizing an iris setting, used in combination with a lamp, for each excitation wavelength for each carousel run in an apparatus for identifying and measuring bacteria in biological samples. The system includes a feedback control loop positioned between a filter wheel and an optical cup for measuring the intensity level of the excitation wavelength, and feeding this information to an iris having an iris setting control device such that the iris setting may be adjusted based upon the measured intensity level to control and optimize the level of light fed to the filter wheel from the lamp. The iris setting can be adjusted so that the level of light fed to the filter wheel remains constant during the lifetime of the lamp and to ensure that the level of light fed to the sample remains below the level at which photo-bleaching occurs.

公开(公告)号：EP2635670A2

公开(公告)日：2013-09-11

申请号：EP11838716.6

申请日：2011-11-02

Applicant: Pocared Diagnostics Inc.

Inventor： INGBER, Gal

IPC: C12M1/34 ,  C12M1/24 ,  C12M1/18 ,  C12Q1/04

CPC classification number: G01N21/0303 ,  B01L3/508 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/028 ,  B01L2200/12 ,  B01L2300/0809 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/168 ,  C12M41/36 ,  G01N21/6452 ,  G01N35/025 ,  G01N2021/0321 ,  G01N2021/0382 ,  G01N2021/6469 ,  G01N2021/6482 ,  G01N2035/00346 ,  G01N2035/0429 ,  G01N2035/0449

Abstract: The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

Abstract translation: 本发明涉及用于进行微生物（例如生物样品中的细菌）的鉴定和定量的系统。 更具体地，本发明涉及一种包括一次性盒和具有锥形表面的光学杯或比色杯的系统; 其中所述壁成角度以允许所述光的更好的涂覆和更好的条纹，包括光学读取器和热控制器的光学系统; 光学分析仪; 冷却系统; 和改进的光谱仪。 该系统可以利用样品处理器中的一次性盒，以及光学分析仪中的光学杯或比色皿。