公开(公告)号：WO2009085990A3

公开(公告)日：2009-09-03

申请号：PCT/US2008087491

申请日：2008-12-18

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  PADI PRATAP REDDY ,  IRENI BABU ,  POLAVARAPU SRINIVAS ,  PADAMATA SHAILAJA ,  NERELLA KAVITHA ,  RAMASAMY VIJAYA ANAND ,  VANGALA RANGA REDDY

Inventor： PADI PRATAP REDDY ,  IRENI BABU ,  POLAVARAPU SRINIVAS ,  PADAMATA SHAILAJA ,  NERELLA KAVITHA ,  RAMASAMY VIJAYA ANAND ,  VANGALA RANGA REDDY

IPC: C07D487/04

CPC classification number: C07D487/04

Abstract: There is provided salts and polymorphs of sitagliptin, processes for the preparation thereof, and pharmaceutical compositions comprising the same.

Abstract translation: 提供西他列汀的盐和多晶型物，其制备方法和包含其的药物组合物。

公开(公告)号：WO2010036904A3

公开(公告)日：2010-07-15

申请号：PCT/US2009058397

申请日：2009-09-25

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  PADI PRATAP REDDY ,  RAMASAMY VIJAYA ANAND ,  IRENI BABU ,  KARROTHU SRIHARI BABU ,  GANTA MADHUSUDHAN REDDY ,  JONNADA KRISHNA ,  POLAVARAPU SRINIVAS ,  YADDANAPUDI VENKATA MADHAVI ,  HALDAR PRANAB ,  VINIGARI KRISHNA ,  PAGADALA NARASIMHA RAO ,  VEDANTHAM RAVINDRA ,  KISARA SATYANARAYANA ,  VETUKURI VENKATA NAGA KALI VARAPRASADA RAJU ,  SUCHITRA SATEESH KAMATH ,  SHANMUGAM SAKTHIVEL ,  MEDISETTI RAMA KRISHNA VENKATA ,  MANUDHANE KUSHAL SURAJMAL

Inventor： PADI PRATAP REDDY ,  RAMASAMY VIJAYA ANAND ,  IRENI BABU ,  KARROTHU SRIHARI BABU ,  GANTA MADHUSUDHAN REDDY ,  JONNADA KRISHNA ,  POLAVARAPU SRINIVAS ,  YADDANAPUDI VENKATA MADHAVI ,  HALDAR PRANAB ,  VINIGARI KRISHNA ,  PAGADALA NARASIMHA RAO ,  VEDANTHAM RAVINDRA ,  KISARA SATYANARAYANA ,  VETUKURI VENKATA NAGA KALI VARAPRASADA RAJU ,  SUCHITRA SATEESH KAMATH ,  SHANMUGAM SAKTHIVEL ,  MEDISETTI RAMA KRISHNA VENKATA ,  MANUDHANE KUSHAL SURAJMAL

IPC: C07D473/18 ,  A61K9/14 ,  A61K9/20 ,  A61K31/52 ,  A61K31/522 ,  C07D473/02

CPC classification number: C07D473/02 ,  Y02P20/582

Abstract: Processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes.

Abstract translation: 制备缬更昔洛韦及其药学上可接受的盐的方法以及该方法的中间体。

公开(公告)号：WO2009085990A2

公开(公告)日：2009-07-09

申请号：PCT/US2008/087491

申请日：2008-12-18

Applicant: DR. REDDY'S LABORATORIES LIMITED ,  DR. REDDY'S LABORATORIES, INC. ,  PADI, Pratap, Reddy ,  IRENI, Babu ,  POLAVARAPU, Srinivas ,  PADAMATA, Shailaja ,  NERELLA, Kavitha ,  RAMASAMY, Vijaya, Anand ,  VANGALA, Ranga, Reddy

Inventor： PADI, Pratap, Reddy ,  IRENI, Babu ,  POLAVARAPU, Srinivas ,  PADAMATA, Shailaja ,  NERELLA, Kavitha ,  RAMASAMY, Vijaya, Anand ,  VANGALA, Ranga, Reddy

IPC: C07D487/04

CPC classification number: C07D487/04

Abstract: There is provided salts and polymorphs of sitagliptin, processes for the preparation thereof, and pharmaceutical compositions comprising the same.

Abstract translation:

本发明提供了盐和西他列汀的多晶型物，它们的制备过程，和药物组合物包含相同的。

公开(公告)号：WO2008077035A2

公开(公告)日：2008-06-26

申请号：PCT/US2007/087924

申请日：2007-12-18

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  GADE, Srinivas Reddy ,  MALLEPALLI, Srinivas Reddy ,  MUVVA, Venkateshwarlu ,  AMIRISETTY, Ravindhranath Tagore ,  HARIKEERTHI, Narasimha Murthy ,  RAMASAMY, Vijaya Anand ,  BANDICHHOR, Rakeshwar ,  MYLAVARAPU, Ravi Kumar ,  KOPPARAPU, Ramachandra Janardana Sarma ,  MANUDHANE, Kushal Surajmal ,  MADDULA, Srinivasula, Reddy

Inventor： GADE, Srinivas Reddy ,  MALLEPALLI, Srinivas Reddy ,  MUVVA, Venkateshwarlu ,  AMIRISETTY, Ravindhranath Tagore ,  HARIKEERTHI, Narasimha Murthy ,  RAMASAMY, Vijaya Anand ,  BANDICHHOR, Rakeshwar ,  MYLAVARAPU, Ravi Kumar ,  KOPPARAPU, Ramachandra Janardana Sarma ,  MANUDHANE, Kushal Surajmal ,  MADDULA, Srinivasula, Reddy

IPC: C07D207/27

CPC classification number: C07D207/27

Abstract: Provided are processes for preparing levetiracetam of the Formula (I):Various aspects and embodiments are provided.

Abstract translation: 提供了制备式（I）的左乙拉西坦的方法：提供了各种方面和实施方案。

公开(公告)号：WO2010036904A2

公开(公告)日：2010-04-01

申请号：PCT/US2009/058397

申请日：2009-09-25

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  PADI, Pratap Reddy ,  RAMASAMY, Vijaya Anand ,  IRENI, Babu ,  KARROTHU, Srihari Babu ,  GANTA, Madhusudhan Reddy ,  JONNADA, Krishna ,  POLAVARAPU, Srinivas ,  YADDANAPUDI, Venkata Madhavi ,  HALDAR, Pranab ,  VINIGARI, Krishna ,  PAGADALA, Narasimha Rao ,  VEDANTHAM, Ravindra ,  KISARA, Satyanarayana ,  VETUKURI, Venkata Naga Kali Varaprasada Raju ,  SUCHITRA, Sateesh Kamath ,  SHANMUGAM, Sakthivel ,  MEDISETTI, Rama Krishna Venkata ,  MANUDHANE, Kushal Surajmal

Inventor： PADI, Pratap Reddy ,  RAMASAMY, Vijaya Anand ,  IRENI, Babu ,  KARROTHU, Srihari Babu ,  GANTA, Madhusudhan Reddy ,  JONNADA, Krishna ,  POLAVARAPU, Srinivas ,  YADDANAPUDI, Venkata Madhavi ,  HALDAR, Pranab ,  VINIGARI, Krishna ,  PAGADALA, Narasimha Rao ,  VEDANTHAM, Ravindra ,  KISARA, Satyanarayana ,  VETUKURI, Venkata Naga Kali Varaprasada Raju ,  SUCHITRA, Sateesh Kamath ,  SHANMUGAM, Sakthivel ,  MEDISETTI, Rama Krishna Venkata ,  MANUDHANE, Kushal Surajmal

IPC: C07D473/18 ,  C07D473/02 ,  A61K31/52 ,  A61K31/522 ,  A61K9/14 ,  A61K9/20

CPC classification number: C07D473/02 ,  Y02P20/582

Abstract: Processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes.

Abstract translation: 制备缬更昔洛韦及其药学上可接受的盐的方法以及该方法的中间体。

公开(公告)号：WO2008077035A3

公开(公告)日：2008-10-09

申请号：PCT/US2007087924

申请日：2007-12-18

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  GADE SRINIVAS REDDY ,  MALLEPALLI SRINIVAS REDDY ,  MUVVA VENKATESHWARLU ,  AMIRISETTY RAVINDHRANATH TAGORE ,  HARIKEERTHI NARASIMHA MURTHY ,  RAMASAMY VIJAYA ANAND ,  BANDICHHOR RAKESHWAR ,  MYLAVARAPU RAVI KUMAR ,  KOPPARAPU RAMACHANDRA JANARDANA SARMA ,  MANUDHANE KUSHAL SURAJMAL ,  MADDULA SRINIVASULA REDDY

Inventor： GADE SRINIVAS REDDY ,  MALLEPALLI SRINIVAS REDDY ,  MUVVA VENKATESHWARLU ,  AMIRISETTY RAVINDHRANATH TAGORE ,  HARIKEERTHI NARASIMHA MURTHY ,  RAMASAMY VIJAYA ANAND ,  BANDICHHOR RAKESHWAR ,  MYLAVARAPU RAVI KUMAR ,  KOPPARAPU RAMACHANDRA JANARDANA SARMA ,  MANUDHANE KUSHAL SURAJMAL ,  MADDULA SRINIVASULA REDDY

IPC: C07D207/27

CPC classification number: C07D207/27

Abstract: A process for preparing levetiracetarn of the Formula (I) via a reaction between S-arnlnobutyramide or its salt: and 4-chlqrobutyrylchloride: which process comprses forming a reaction mixture that includes, the S-aminsbutyrarriide or its salt, the 4-chlorobutyrylchloride, and potassium hydroxide, wherein the potassium hydroxide is added to said reaction mixture in a lot-wise manner...

Abstract translation: 通过S-氨基异丁酰胺或其盐与4-氯丁酰氯的反应来制备式（I）的左乙拉西那嗪的方法：该方法包括形成包含S-氨基丁二酰亚胺或其盐的4-氯丁酰氯的反应混合物， 和氢氧化钾，其中将氢氧化钾以很多方式加入到所述反应混合物中...

公开(公告)号：US07335686B2

公开(公告)日：2008-02-26

申请号：US10747671

申请日：2003-12-30

Applicant: Kanury Venkata Subba Rao ,  Mohan Ramachandran Wani ,  Venkatasamy Manivel ,  Parameswaran Perunninakulath Subrayan ,  Vinod Kumar Singh ,  Ramasamy Vijaya Anand ,  Ehrlich Desa ,  Gyan Chandra Mishra ,  Anil Chatterji

Inventor： Kanury Venkata Subba Rao ,  Mohan Ramachandran Wani ,  Venkatasamy Manivel ,  Parameswaran Perunninakulath Subrayan ,  Vinod Kumar Singh ,  Ramasamy Vijaya Anand ,  Ehrlich Desa ,  Gyan Chandra Mishra ,  Anil Chatterji

IPC: A61K31/195

CPC classification number: A61K31/255 ,  A61K31/16 ,  A61K31/185 ,  A61K31/19 ,  A61K31/194 ,  A61K31/195 ,  C07C305/06 ,  C07C307/02 ,  C07C309/17 ,  C07C309/18

Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.

Abstract translation: 本发明涉及可用作破骨细胞发生抑制剂的新型酸性氨基酸/二羧酸衍生物（天然氨基酸的磺酸/硫酸衍生物及其酰胺）。 本发明还提供了使用通式为ZOC-（CRR）m -COOH的新型酸性氨基酸/二羧酸衍生物的方法，其中：m = 2,3或4; Z是OH或NH 2; 该化合物中的一个R是由SO 3 H，OSO 3 H，CH 2 -SO 3， H，CH 2 -SO 2 SO 3，NHSO 3 H，剩余的R 5是H或NH 2， / SUB>，用于抑制破骨细胞发生。