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    SELF-ALIGNING NOZZLE ARRAY FOR PIPETTE TIP ARRAY PLATE
    3.
    发明申请
    SELF-ALIGNING NOZZLE ARRAY FOR PIPETTE TIP ARRAY PLATE 审中-公开

    公开(公告)号：WO2002045857A3

    公开(公告)日：2002-06-13

    申请号：PCT/US2001/046319

    申请日：2001-12-04

    Applicant: ROBBINS SCIENTIFIC CORPORATION ,  STANCHFIELD, Jim, E. ,  WRIGHT, Dave, J. ,  ROBINSON, David ,  ROBBINS, Paul, B. ,  CHRISTENSEN, Kenneth, J.

    Inventor： STANCHFIELD, Jim, E. ,  WRIGHT, Dave, J. ,  ROBINSON, David ,  ROBBINS, Paul, B. ,  CHRISTENSEN, Kenneth, J.

    IPC: G01N1/00

    Abstract: An apparatus (10) for dispensing liquid in conjunction with an array of pipette tips (14), where each pipette tip (36) includes a socket portion (42). The liquid dispensing apparatus (10) includes tubes (25), each including a barrel (28) and a lower end (33), and a nozzle (34), each nozzle (34) having a shoulder (68) and a mouth (44) configured of appropriate diameter to enter into the socket portion (42) of each pipette tip (36), and form a liquid-tight seal therewith. A bottom plate (24) includes a number of through-holes (72) through which each of the nozzles passes (34). The through holes (72) are of larger diameter than the nozzles (34) so that limited lateral movement is allowed. A second embodiment (100) is convertible, so that separation of upper (73) and lower boundaries (75) may be decreased such that the upper boundary (73) contacts the shoulders (68) of said nozzles (34), to hold the nozzles (34) in fixed position, for use with pipette tip arrays (96) which are not bound together in fixed spatial relation to each other, but which are themselves allowed limited lateral movement. Both embodiments (10, 100) may further include a shucker plate (50) such that when the shucker plate (50) is made to travel away from the bottom plate (24) by an ejection mechanism (85), the pipette tips (36, 97) are pushed off of the nozzle mouths (44).

    COMPARTMENTALIZED MULTI-WELL CONTAINER
    4.
    发明申请
    COMPARTMENTALIZED MULTI-WELL CONTAINER 审中-公开
    隔音多层容器

    公开(公告)号：WO1997006890A1

    公开(公告)日：1997-02-27

    申请号：PCT/US1996012985

    申请日：1996-08-09

    Applicant: ROBBINS SCIENTIFIC CORPORATION ,  ROBBINS, Paul, B.

    Inventor： ROBBINS SCIENTIFIC CORPORATION

    IPC: B01L03/00

    CPC classification number: B01L3/50851 ,  B01L3/5085 ,  B01L2300/0893

    Abstract: A multi-well container (10) is provided in which a greater number of wells may exist than heretofore possible while still maintaining a standard multi-well plate tube array format and footprint. The multi-well container (10) is comprised of a rectangular array of tubes (12) in standard tube format held together by an integrally fashioned plate portion (16). The tubes (12) are subdivided by partitions or septa (14) which extend the height of the tubes (12). Each septum (14) may constitute a single wall or may be comprised of any number of fins (32) which are integral with internal tube surfaces (28). In a symmetrical design with four such fins (32), the fins (32) radiate at angular intervals of 90 degrees from a common central axis (34) with which all four fins (32) are integral. Thus, the septa (14) serve to compartmentalize each tube (12) into symmetrical quadrants of four smaller wells or sub-tubes (30). The preferred embodiment is directed toward usage in conjunction with PCR thermal cyclers, but the multi-well container (10) and the elements as are embodied therein are generally applicable to any laboratory procedure where multiple samples must be treated, evaluated, or stored.

    Abstract translation: 提供了一种多孔容器（10），其中可以存在比迄今为止更多的孔，同时仍保持标准的多孔板管阵列格式和占地面积。 多孔容器（10）由标准管形式的由整体形成的板部分（16）保持在一起的矩形管阵列（12）组成。 管（12）通过延伸管（12）的高度的隔板（14）细分。 每个隔膜（14）可以构成单个壁，或者可以由与内部管表面（28）成一体的任何数量的翅片（32）构成。 在具有四个这样的翅片（32）的对称设计中，翅片（32）以与所有四个翼片（32）为一体的公共中心轴线（34）成90度的角度间隔辐射。 因此，隔片（14）用于将每个管（12）分隔成四个较小孔或子管（30）的对称象限。 优选实施方案涉及与PCR热循环仪结合使用，但是多孔容器（10）和其中体现的元件通常可应用于必须处理，评估或储存多个样品的任何实验室程序。

    RECIPROCATING BATH SHAKER
    5.
    发明申请
    RECIPROCATING BATH SHAKER 审中-公开
    复制浴袍

    公开(公告)号：WO1997011773A1

    公开(公告)日：1997-04-03

    申请号：PCT/US1996015461

    申请日：1996-09-27

    Applicant: ROBBINS SCIENTIFIC CORPORATION

    Inventor： ROBBINS SCIENTIFIC CORPORATION

    IPC: B01F11/00

    CPC classification number: B01F11/0014 ,  B01L7/02

    Abstract: A bath shaker (10) is provided for agitating liquid baths. The bath shaker (10) incorporates a "flexible parallelogram" mode of movement wherein a bath shelf (20) is attached to and supported by two, parallel opposing flexible arms (112). Present on each flexible arm (112) is a first attachment portion (124) sandwichedly held by an upright extension (120) and a first hold plate (110), the arrangement causing the first attachment portion (124) to serve as a flexible hinge. A drive mechanism (16) produces a reciprocating action of the bath shelf (20) through the use of an eccentric (80) and a pivoting lever (46) attached to both the eccentric (80) and the bath shelf (20). The flexible parallelogram arrangement defines the reciprocating motion to be substantially rectilinear and makes for an entirely noiseless mode of travel, while producing an extremely smooth transition between reciprocations. Two bath containers (24) are supported by the bath shelf (20) and are provided with a highly accurate temperature control system (26).

    Abstract translation: 提供用于搅拌液浴的洗浴摇床（10）。 洗浴摇床（10）包含“柔性平行四边形”运动模式，其中浴架（20）附接到两个平行的相对的柔性臂（112）并由其支撑。 存在于每个柔性臂（112）上的是由直立延伸部（120）和第一保持板（110）夹持的第一附接部分（124），该第一连接部分使得第一附接部分（124）用作柔性铰链 。 驱动机构（16）通过使用偏心轮（80）和附接到偏心轮（80）和浴架（20）两者的枢转杆（46）来产生浴架（20）的往复运动。 柔性平行四边形布置将往复运动定义为基本上直线的，并且使得完全无声的行进模式，同时在往复运动之间产生非常平滑的过渡。 两个洗浴容器（24）由浴架（20）支撑，并设置有高精度的温度控制系统（26）。

    RECIPROCATING BATH SHAKER
    6.
    发明公开
    RECIPROCATING BATH SHAKER 失效
    往复浴摇床

    公开(公告)号：EP0852514A1

    公开(公告)日：1998-07-15

    申请号：EP96933916.0

    申请日：1996-09-27

    Applicant: ROBBINS SCIENTIFIC CORPORATION

    Inventor： NEUMANN, Hans, D. ,  ROBBINS, Arthur, J. ,  WRIGHT, David, J.

    IPC: B01F11 ,  B01L7

    CPC classification number: B01F11/0014 ,  B01L7/02

    Abstract: A bath shaker (10) is provided for agitating liquid baths. The bath shaker (10) incorporates a 'flexible parallelogram' mode of movement wherein a bath shelf (20) is attached to and supported by two, parallel opposing flexible arms (112). Present on each flexible arm (112) is a first attachment portion (124) sandwichedly held by an upright extension (120) and a first hold plate (110), the arrangement causing the first attachment portion (124) to serve as a flexible hinge. A drive mechanism (16) produces a reciprocating action of the bath shelf (20) through the use of an eccentric (80) and a pivoting lever (46) attached to both the eccentric (80) and the bath shelf (20). The flexible parallelogram arrangement defines the reciprocating motion to be substantially rectilinear and makes for an entirely noiseless mode of travel, while producing an extremely smooth transition between reciprocations. Two bath containers (24) are supported by the bath shelf (20) and are provided with a highly accurate temperature control system (26).

    Abstract translation: 浴缸摇床（10）用于搅动液体浴缸。 沐浴摇床（10）结合了“柔性平行四边形”运动模式，其中沐浴架（20）附接到两个平行相对的柔性臂（112）并由其支撑。 存在于每个柔性臂112上的是由直立延伸部120和第一保持板110夹持地夹持的第一附接部124， 。 驱动机构（16）通过使用连接到偏心轮（80）和沐浴搁架（20）的偏心轮（80）和枢转杠杆（46）产生浴盆（20）的往复运动。 柔性平行四边形装置将往复运动定义为基本直线的并且使得完全无噪音的行进模式，同时在往复运动之间产生非常平滑的过渡。 两个浴槽（24）由浴架（20）支撑，并设置有高度精确的温度控制系统（26）。

    MULTI-WELL ARRAY WITH ADJUSTABLE PLENUM
    7.
    发明公开
    MULTI-WELL ARRAY WITH ADJUSTABLE PLENUM 审中-公开
    具有调节腔室多HOLE MATRIX

    公开(公告)号：EP1156879A1

    公开(公告)日：2001-11-28

    申请号：EP00919269.1

    申请日：2000-02-04

    Applicant: ROBBINS SCIENTIFIC CORPORATION

    Inventor： STANCHFIELD, James, E. ,  WRIGHT, David, J. ,  BAILEY, Chris, N. ,  ROBBINS, Paul, B.

    IPC: B01L3/00 ,  B01L9/00 ,  B01L11/00

    CPC classification number: B01L3/5025 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00335 ,  B01J2219/00351 ,  B01J2219/00585 ,  C40B60/14

    Abstract: An apparatus for multiple simultaneous synthesis (110), having a number of vials (28), each vial (28) having an upper end (31), a lower end (30), and a barrel (29), the upper end (31) opening into a mouth (32). It also includes a lower frame assembly (181) having a number of holes (101, 103, 105) for receiving the vials (28), and an upper frame assembly (180), which includes inner side-walls (195) and a ceiling portion (190). A gas-tight seal (197) surrounds a plenum (85), the plenum (85) being formed between the ceiling portion (190) of the upper frame assembly (180) and the lower frame assembly (181). The plenum (85) is adjustable in volume by the positioning of the upper frame assembly (180) in variable relation to the lower frame assembly (181), while maintaining the gas-tight seal (197). The volume of the plenum (85) is adjustable to a minimum whereby the mouths (32) of the vials (28) are sealed by the ceiling (190) of the gas-tight seal (197), which is optionally an upper gasket (90). Also disclosed is a plenum enclosure (182) for multiple simultaneous synthesis used in conjunction with vials (28), which includes the upper frame assembly (180) and lower frame assembly (181) and the gas-tight seal (197), as well as a gasket vial holder (185) to be used in the plenum enclosure (182).

    COMPARTMENTALIZED MULTI-WELL CONTAINER
    8.
    发明公开
    COMPARTMENTALIZED MULTI-WELL CONTAINER 失效
    与下多个孔SPLIT CONTAINER

    公开(公告)号：EP0843593A1

    公开(公告)日：1998-05-27

    申请号：EP96928113.0

    申请日：1996-08-09

    Applicant: ROBBINS SCIENTIFIC CORPORATION

    Inventor： ROBBINS, Paul, B.

    IPC: B01L3

    CPC classification number: B01L3/50851 ,  B01L3/5085 ,  B01L2300/0893

    Abstract: A multi-well container (10) is provided in which a greater number of wells may exist than heretofore possible while still maintaining a standard multi-well plate tube array format and footprint. The multi-well container (10) is comprised of a rectangular array of tubes (12) in standard tube format held together by an integrally fashioned plate portion (16). The tubes (12) are subdivided by partitions or septa (14) which extend the height of the tubes (12). Each septum (14) may constitute a single wall or may be comprised of any number of fins (32) which are integral with internal tube surfaces (28). In a symmetrical design with four such fins (32), the fins (32) radiate at angular intervals of 90 degrees from a common central axis (34) with which all four fins (32) are integral. Thus, the septa (14) serve to compartmentalize each tube (12) into symmetrical quadrants of four smaller wells or sub-tubes (30). The preferred embodiment is directed toward usage in conjunction with PCR thermal cyclers, but the multi-well container (10) and the elements as are embodied therein are generally applicable to any laboratory procedure where multiple samples must be treated, evaluated, or stored.

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