Abstract:
A fluid handling system for transferring fluids is disclosed. The fluid handling system incorporates a plurality of transfer units for dispensing and/or collecting fluids as part of a closed analytical system. The plurality of transfer units are capable of functioning independently and/or collectively when assembled in a unitary array format. Methods of making and using the fluid handling system are also disclosed. The fluid handling system allows a sub-array of transfer units to shift in a vertical direction independent from a position of another sub-array of transfer units that are assembled within the same fluid head. Therefore, the fluid handling system facilitates multi-port fluid delivery and collection in an array format. Further, the fluid handling system aligned with a sensing surface enables label-free detection assays to be performed in an analytical system.
Abstract:
A microplate device for performing flow-through assays is disclosed. The device includes an array of chambers or channels accessible by way of multiple ports or transfer units of a fluid dispensing system. Ports in the covering or closure of the device permit entrance of fluid into the inlet ports through a channel to the outlet ports. A sealing interface between the device and the multiple transfer units includes the ports and forms a closed analytical array of flow-through channels. Methods of making and using the device are also disclosed such that a sealing interface between the device and a fluid dispensing system permits continuous flow-through assays in a closed system. A sensing surface included in the closed system enables label-free detection of flow-through assays performed in the device.
Abstract:
Described herein are methods of producing an aluminide barrier layer, wherein the barrier layer includes nickel aluminide, iron aluminide, or a combination thereof, and the barrier layer is produced by a diffusion coating process on at least one surface of the article. The methods described herein are useful for preventing or reducing the migration of a metal species at or near at least one surface of the article. The articles produced by the methods described herein have numerous applications in the construction and operation of fuel cells.
Abstract:
Described herein are methods of producing an aluminide barrier layer, wherein the barrier layer includes nickel aluminide, iron aluminide, or a combination thereof, and the barrier layer is produced by a diffusion coating process on at least one surface of the article. The methods described herein are useful for preventing or reducing the migration of a metal species at or near at least one surface of the article. The articles produced by the methods described herein have numerous applications in the construction and operation of fuel cells.
Abstract:
Capacitive devices are described having electrical isolators for electrodes which possess efficient electrical contact between current collectors, electrical isolation of electrodes, and/or electrochemical stability, while minimizing the mechanical stress and strain applied to the electrodes. The capacitive devices are adaptable to a wide range of electrode diameters and electrode stack lengths.