公开(公告)号：WO0230446A3

公开(公告)日：2003-07-24

申请号：PCT/US0132044

申请日：2001-10-12

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  REDL HEINZ ,  SPAETHE REINER ,  SIMUNEK MANUELA

Inventor： REDL HEINZ ,  SPAETHE REINER ,  SIMUNEK MANUELA

IPC: A61K38/36 ,  A61P41/00

CPC classification number: A61K38/363

Abstract: Reducing or preventing adhesions which would form in a patient during or after surgery by administering to the wound surface of a patient a fibrinogen solution in an amount of about 0.025 ml fibrinogen/cm to about 0.25 ml fibrinogen/cm of the surface being at risk for developing adhesions. User of fibrinogen in a preparation comprising fibrinogen at a concentration of 20 to 80 mg/ml for the reduction or prevention of post-surgical adhesion formation.

Abstract translation: 通过向患者的伤口表面施用约0.025ml纤维蛋白原/ cm 2至约0.25ml纤维蛋白原/ cm 2的量的纤维蛋白原溶液来减少或预防在手术期间或手术后形成的粘连 表面有发生粘连的风险。 用于包含浓度为20至80mg / ml的纤维蛋白原的制剂中的纤维蛋白原用于减少或防止手术后粘连形成。