Abstract:
Device and method for rapid extraction of body tissue from an enclosed body cavity. Hollow entry cannula with optional core element provides entry into body tissue space such as bone marrow. Aspiration cannula is inserted through entry cannula into body tissue and is manipulated to advance directionally through body cavity. Optional stylet within aspiration cannula aids in advancing aspiration cannula through body tissue and is removed to facilitate extraction of body tissue through the aspiration cannula. Inlet openings near distal tip of aspiration cannula allow tissue aspiration, with negative pressure source at proximal end of aspiration cannula providing controlled negative pressure. Aspiration cannula may be withdrawn and its path adjusted for multiple entries through the same entry point, following different paths through tissue space for subsequent aspiration of more tissue.
Abstract:
PROBLEM TO BE SOLVED: To provide a device and method for rapid extraction of body tissue from an enclosed body cavity.SOLUTION: A hollow entry cannula 101 provides entry into body tissue space. An aspiration cannula 105 is inserted through an entry cannula 101 into body tissue and is manipulated to advance directionally through body cavity. An optional stylet 106 aids in advancing aspiration cannula 105 through body tissue and is removed to facilitate extraction of body tissue through the aspiration cannula 105. A negative pressure source at proximal end of the aspiration cannula 105 provides controlled negative pressure, and tissue is collected from an inlet openings near a distal tip 130. The aspiration cannula 105 may be inserted for multiple entries through the same entry point, following different paths through tissue space for subsequent aspiration of more tissue.
Simplified title:治疗黄病毒科病毒感染之方法、治疗黄病毒科病毒感染之组合物及用于鉴定供治疗黄病毒科病毒感染之组合物的筛选检测法 METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION
Abstract in simplified Chinese:简言之,本揭示案之实施例包括组合物、医药组合物、治疗经黄病毒(Flaviviridae)科病毒之病毒感染的宿主之方法、治疗宿主中HCV复制之方法、抑制宿主中NS4B多 与HCV负链RNA之3'UTR结合之方法、治疗宿主之肝脏纤维化的方法、鉴定用以治疗C型肝炎病毒(HCV)感染之候选药剂之方法,及其类似方法。
Abstract:
A thyristor device can be used to implement a variety of semiconductor memory circuits, including high-density memory-cell arrays and single cell circuits. In one example embodiment, the thyristor device includes doped regions of opposite polarity, and a first word line that is used to provide read and write access to the memory cell. A second word line is located adjacent to and separated by an insulative material from one of the doped regions of the thyristor device for write operations to the memory cell, for example, by enhancing the switching of the thyristor device from a high conductance state to a low conductance state and/or from the low conductance state to the high conductance. This type of memory circuit can be implemented to significantly reduce standby power consumption and access time.
Abstract:
A thyristor device can be used to implement a variety of semiconductor memory circuits, including high-density memory-cell arrays and single cell circuits. In one example embodiment, the thyristor device includes doped regions of opposite polarity, and a first word line that is used to provide read and write access to the memory cell. A second word line is located adjacent to and separated by an insulative material from one of the doped regions of the thyristor device for write operations to the memory cell, for example, by enhancing the switching of the thyristor device from a high conductance state to a low conductance state and/or from the low conductance state to the high conductance. This type of memory circuit can be implemented to significantly reduce standby power consumption and access time.
Abstract:
The present invention relates to the treatment of Epidermolysis Bullosa, particularly the recessive dystrophic subtype (RDEB), using the Clustered- Regularly Interspaced Short Palindromic Repeats (CRISPR) system. This technology offers the possibility to design a single guide RNA (sgRNA) which is incorporated into a CRISPR- associated protein (Cas9) to recognize and induce DNA double-strand breaks at a specific target location. DNA double-strand breaks will be repaired by homologous recombination (HR) in the presence of a donor sequence for Epidermolysis Bullosa gene repair. In the context of Epidermolysis Bullosa, this allows to repair the mutation/s causing the disease.
Abstract:
Systems and methods for representing and diagnosing interaction sequences in accordance embodiments of the invention are disclosed. In one embodiment of the invention, a group interaction diagnosis and recommendation server system includes a processor and a memory configured to store a set of reference interaction data, where the reference interaction data includes a set of reference interaction sequences, wherein a group interaction diagnosis application configures the processor to obtain a set of group interaction data, generate an interaction model based on the group interaction data and an interaction dynamics language, determine at least one interaction sequence within the set of group interaction data based on the generated interaction model, identify at least one matching interaction sequence within the determined at least one interaction sequence, and recommend at least one improved interaction sequence based on the identified at least one matching interaction sequence and the set of reference interaction data.
Abstract:
In a fuel cell comprising a tubular casing, an electrolyte layer received in the tubular casing, and a pair of gas diffusion electrodes interposing the electrolyte layer and defining a fuel gas passage and an oxidizing gas passage, respectively, each gas diffusion electrode is formed by stacking a plurality of layers of material therefor, for instance in the axial direction of the casing. Because the gas diffusion layers are formed layer by layer, components can be formed in highly fine patterns so that a highly compact tubular fuel cell can be achieved. Similarly, the dimensions of the various elements of the fuel cell can be controlled in a highly accurate manner. Also, the geometric arrangement can be changed at will in intermediate parts of each gas passage.