公开(公告)号：CA438990A

公开(公告)日：1947-01-07

申请号：CA438990D

Applicant: STEWART ANDREW GEORGE

Inventor： STEWART ANDREW GEORGE

公开(公告)号：WO1991002799A1

公开(公告)日：1991-03-07

申请号：PCT/AU1990000373

申请日：1990-08-24

Applicant: BIOTECHNOLOGY AUSTRALIA PTY LTD ,  RUSSELL-JONES, Gregory, John ,  STEWART, Andrew, George ,  TSONIS, Con, George

Inventor： BIOTECHNOLOGY AUSTRALIA PTY LTD

IPC: C12N15/62

CPC classification number: C07K7/23 ,  A61K38/00 ,  A61K39/00 ,  C07K14/245 ,  C07K2319/00 ,  C07K2319/035 ,  C07K2319/75 ,  Y10S424/811 ,  Y10S930/13

Abstract: This invention relates to the preparation of novel fusion proteins which comprise an analogue of LHRH and TraTp or an analogue of TraTp. The fusion proteins of the invention are useful as components of vaccines for the inhibition or control of reproductive functions in vertebrate hosts. The invention also relates to polynucleotide molecules encoding the fusion proteins, to transformant hosts expressing the fusion proteins and to methods of inhibiting or controlling reproductive function in vertebrate hosts using the fusion proteins or vaccines of the invention.

Abstract translation: 本发明涉及新型融合蛋白的制备，其包含LHRH和TraTp的类似物或TraTp的类似物。 本发明的融合蛋白可用作在脊椎动物宿主中抑制或控制生殖功能的疫苗的组分。 本发明还涉及编码融合蛋白的多核苷酸分子，表达融合蛋白的转化体宿主以及使用本发明的融合蛋白或疫苗在脊椎动物宿主中抑制或控制生殖功能的方法。