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    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT
    4.
    发明申请
    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT 审中-公开
    LV阈值测量和捕获管理

    公开(公告)号：WO2006069032A1

    公开(公告)日：2006-06-29

    申请号：PCT/US2005/046054

    申请日：2005-12-20

    Applicant: MEDTRONIC, INC. ,  SHELDON, Todd, J. ,  STROEBEL, John, C. ,  PARIKH, Purvee, Praduman ,  KLECKNER, Karen, J.

    Inventor： SHELDON, Todd, J. ,  STROEBEL, John, C. ,  PARIKH, Purvee, Praduman ,  KLECKNER, Karen, J.

    IPC: A61N1/37

    CPC classification number: A61N1/3627 ,  A61N1/3684 ,  A61N1/371

    Abstract: The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate o ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or "CRT").

    Abstract translation: 本发明提供了用于在非跟踪起搏模式（例如，DDI / R，VVI / R）中确定心室起搏刺激是否捕获节奏心室的方法和装置，包括以下方面中的一些或全部。 例如，将心室起搏速率提高到高于最近的心率的超速起搏速率的标称值，并评估从第一起搏心室到第二感测心室的传导间隔，然后继续监测潜在的速率o确保 阈值测试起搏速率不会超过预定的最小间隔，并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是子阈值和超阈值之一。 所述方法和装置与确保心室起搏方案（例如，心脏再同步治疗或“CRT”）的实际递送相结合特别有用。

    SOFTWARE CONFIGURABLE MEDICAL DEVICE PLATFORM
    6.
    发明申请
    SOFTWARE CONFIGURABLE MEDICAL DEVICE PLATFORM 审中-公开
    软件可配置医疗设备平台

    公开(公告)号：WO2006044406A1

    公开(公告)日：2006-04-27

    申请号：PCT/US2005/036562

    申请日：2005-10-13

    Applicant: MEDTRONIC, INC. ,  DENO, D. Curtis ,  WILKINSON, Jeffrey, D. ,  STROEBEL, John, C.

    Inventor： DENO, D. Curtis ,  WILKINSON, Jeffrey, D. ,  STROEBEL, John, C.

    IPC: A61N1/365

    CPC classification number: A61N1/3625 ,  A61N1/365 ,  A61N1/3956

    Abstract: A new design platform for implantable and external medical devices such as pacemakers, defibrillators, neurostimulators, heart monitors, etc. is provided. A real-time, highly flexible system of software and hardware modules enables both phototypes and products to respond to patient and customer needs with greater design and manufacturing efficiency. Certain embodiments integrate a general-purpose processor with interface circuitry to provide a standard platform for implement. The invention relates to medical devices such as pacemakers, pulse generators, cardioverter-defibrillators and the like and more particularly relates to modular and reconfigurable medical system platforms and methods of designing, testing, controlling and implementing diverse therapies, diagnostics, physiologic sensors and related instrumentation using said medical system platforms. Methods, systems and devices provide a new design platform for implantable and external medical devices such as pacemakers, defibrillators, neurostimulators, heart monitors, etc. A real-time, highly flexible system of software and hardware modules enables both prototypes and products to respond.

    Abstract translation: 提供了一种用于植入式和外部医疗设备（如起搏器，除颤器，神经刺激器，心脏监护仪等）的新设计平台。 实时，高度灵活的软件和硬件模块系统使照片和产品能够以更高的设计和制造效率满足患者和客户的需求。 某些实施例将通用处理器与接口电路集成以提供用于实现的标准平台。 本发明涉及诸如起搏器，脉冲发生器，心律转复除颤器等的医疗装置，更具体地涉及模块化和可重构医疗系统平台以及设计，测试，控制和实施多种疗法，诊断，生理传感器和相关仪器的方法 使用医疗系统平台。 方法，系统和设备为植入式和外部医疗设备（如起搏器，除颤器，神经刺激器，心脏监测器等）提供了一个新的设计平台。实时，高度灵活的软件和硬件模块系统使原型和产品都能够响应。

    FULLY INHIBITED DUAL CHAMBER PACING MODE
    7.
    发明申请
    FULLY INHIBITED DUAL CHAMBER PACING MODE 审中-公开
    完全禁止双室模式

    公开(公告)号：WO2005097259A1

    公开(公告)日：2005-10-20

    申请号：PCT/US2005/009776

    申请日：2005-03-23

    Applicant: MEDTRONIC, INC. ,  STROEBEL, John, C.

    Inventor： STROEBEL, John, C.

    IPC: A61N1/368

    CPC classification number: A61N1/368 ,  A61N1/3688

    Abstract: A pacing mode is provided, in one embodiment, that permits missed or skipped ventricular beats. The mode monitors a full cardiac cycle (A-A interval) for the presence of intrinsic ventricular activity. If ventricular activity is present, a flag is set that is valid for the next cardiac cycle. At the beginning of the next cardiac cycle, the device determines if the flag is present. So long as the flag is present, the device will not deliver a ventricular pacing pulse in that cycle, even if there is no intrinsic ventricular activity. If there is no flag present at the start of a given cardiac cycle, a ventricular pacing pulse is delivered and this ventricular activity sets a flag for the subsequent cardiac cycle.

    Abstract translation: 在一个实施例中，提供允许错过或跳过的心室搏动的起搏模式。 该模式监测整个心脏周期（A-A间隔）是否存在内部心室活动。 如果存在心室活动，则设置对下一个心动周期有效的标志。 在下一个心动周期的开始，该装置确定该标志是否存在。 只要标志存在，即使没有内在的心室活动，该装置也不会在该周期内递送心室起搏脉冲。 如果在给定的心脏周期的开始处没有标志，则输送心室起搏脉冲，并且该心室活动为随后的心动周期设置标志。

    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT
    8.
    发明申请
    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT 审中-公开
    LV阈值测量和捕获管理

    公开(公告)号：WO2007073514A1

    公开(公告)日：2007-06-28

    申请号：PCT/US2006/060813

    申请日：2006-11-13

    Applicant: MEDTRONIC, INC. ,  PAIRKH, Purvee, P. ,  STROEBEL, John, C. ,  SHELDON, Todd, J. ,  KLECKNER, Karen, J.

    Inventor： PAIRKH, Purvee, P. ,  STROEBEL, John, C. ,  SHELDON, Todd, J. ,  KLECKNER, Karen, J.

    IPC: A61N1/362 ,  A61N1/37

    CPC classification number: A61N1/3627 ,  A61N1/3684 ,  A61N1/371

    Abstract: The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate to ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or "CRT").

    Abstract translation: 本发明提供了用于在非跟踪起搏模式（例如，DDI / R，VVI / R）中确定心室起搏刺激是否捕获节奏心室的方法和装置，包括以下方面的一些或全部。 例如，将心室起搏速率增加到高于最近心率的超速起搏速率的标称值，并评估从第一起搏心室到第二感测心室的传导间隔，然后继续监测潜在速率，以确保 阈值测试起搏速率不会超过预定的最小间隔，并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是亚阈值和超阈值之一。 所述方法和装置与确保心室起搏方案（例如，心脏再同步治疗或“CRT”）的实际递送相结合特别有用。

    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT
    9.
    发明申请
    LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT 审中-公开
    LV阈值测量和捕获管理

    公开(公告)号：WO2006069032A9

    公开(公告)日：2006-08-31

    申请号：PCT/US2005046054

    申请日：2005-12-20

    Applicant: MEDTRONIC INC ,  SHELDON TODD J ,  STROEBEL JOHN C ,  PARIKH PURVEE PRADUMAN ,  KLECKNER KAREN J

    Inventor： SHELDON TODD J ,  STROEBEL JOHN C ,  PARIKH PURVEE PRADUMAN ,  KLECKNER KAREN J

    IPC: A61N1/37

    CPC classification number: A61N1/3627 ,  A61N1/3684 ,  A61N1/371

    Abstract: The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate o ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or "CRT").

    Abstract translation: 本发明提供了用于在非跟踪起搏模式（例如，DDI / R，VVI / R）中确定心室起搏刺激是否正在俘获起搏心室的方法和设备，包括以下方面中的一些或全部。 例如，将心室起搏频率增加一个名义量至高于最近心率的超速起搏频率，并评估从第一起搏心室至第二心室的传导时间间隔，然后继续监测基础频率o确保 阈值测试起搏速率将不超过预定的最小时间间隔，并向第一心室提供起搏刺激并感测第二心室以确定对第一心室的起搏刺激是否是亚阈值和超阈值之一。 该方法和装置在确保心室起搏方案（例如心脏再同步治疗或“CRT”）的实际输送方面特别有用。

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