公开(公告)号：WO2010035631A1

公开(公告)日：2010-04-01

申请号：PCT/JP2009/065614

申请日：2009-09-02

Applicant: NISSEI PLASTIC INDUSTRIAL CO., LTD. ,  ART METAL MFG. CO., LTD. ,  SATO, Tomoyuki ,  SUGANUMA, Masashi ,  KARASAWA, Tomonori ,  KANAI, Shoji ,  MATSUMOTO, Akira

Inventor： SATO, Tomoyuki ,  KARASAWA, Tomonori ,  KANAI, Shoji ,  MATSUMOTO, Akira

IPC: F02F3/10 ,  F02F7/00 ,  C25D15/00

CPC classification number: C25D15/00 ,  C25D3/20 ,  C25D15/02 ,  F02F3/10 ,  F02F7/0085 ,  F05C2201/021 ,  F05C2201/0436 ,  F05C2203/0808 ,  F05C2251/048 ,  F05C2251/10 ,  F05C2253/04 ,  Y10T428/12757

Abstract: A technique for using an iron plating for coating an aluminum product that results in adequate durability. An aluminum piston (lθ) used as a plated aluminum product is covered by an iron-based composite plating layer (l l). The iron-based composite plating layer (ll) contains a carbon nanomaterial, which is applied to the aluminum-based base material using a iron-based composite plating bath formed by mixing a carbon nanomaterial into an iron plating bath.

Abstract translation: 一种使用铁电镀涂覆铝制品的技术，其产生足够的耐久性。 用作镀覆铝产品的铝活塞（1'）被铁基复合镀层（11）覆盖。 铁基复合镀层（II）含有碳纳米材料，其使用通过将碳纳米材料混合到镀铁浴中而形成的铁基复合电镀浴将其应用于铝基基材。

公开(公告)号：WO2008139943A1

公开(公告)日：2008-11-20

申请号：PCT/JP2008/058315

申请日：2008-04-24

Applicant: Nissei Plastic Industrial Co., Ltd. ,  ARAI, Keita ,  KATO, Atsushi ,  SUGANUMA, Masashi

Inventor： ARAI, Keita ,  KATO, Atsushi ,  SUGANUMA, Masashi

IPC: C01B31/02 ,  C22C49/14

CPC classification number: C22C47/04 ,  C22C47/08 ,  C22C49/06

Abstract: A method of manufacturing a metal-carbon nanocomposite material in which aluminum is used as the matrix is disclosed. The manufacturing method comprises mixing a Si-coated carbon nanomaterial (30) and a powdered Mg material (33), heating the mixture to a melting point of the Mg material or higher, and thereafter cooling the mixture to obtain an Mg-carbon nanomaterial (34). A metal-carbon nanomaterial in which Al is used as the matrix is provided by cooling the Mg-carbon nanomaterial and molten Al (40) in a mixed state.

Abstract translation: 公开了使用铝作为基体的金属 - 碳纳米复合材料的制造方法。 制造方法包括将Si包覆的碳纳米材料（30）和粉末状Mg材料（33）混合，将混合物加热至Mg材料或更高的熔点，然后冷却该混合物以获得Mg-碳纳米材料（ 34）。 通过将Mg-碳纳米材料和熔融的Al（40）以混合状态进行冷却来提供使用Al作为基体的金属 - 碳纳米材料。

公开(公告)号：WO0121771A3

公开(公告)日：2002-02-14

申请号：PCT/IB0001438

申请日：2000-09-21

Applicant: CANBAS CO LTD ,  SUGANUMA MASASHI ,  KAWABE TAKUMI

Inventor： SUGANUMA MASASHI ,  KAWABE TAKUMI

IPC: G01N33/50 ,  A61K31/506 ,  A61K31/704 ,  A61K33/24 ,  A61K35/76 ,  A61K38/00 ,  A61K38/04 ,  A61K45/00 ,  A61K48/00 ,  A61P35/00 ,  A61P43/00 ,  C07H15/252 ,  C07K14/16 ,  C07K14/47 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/12 ,  C12N9/16 ,  C12N9/99 ,  C12N15/09 ,  C12N15/11 ,  C12N15/62 ,  C12Q1/48 ,  G01N33/15 ,  G01N33/53 ,  G01N33/566 ,  G01N33/574 ,  G01N33/68

CPC classification number: C07K14/4738 ,  A61K38/00 ,  A61K48/00 ,  C07K2319/00

Abstract: The invention provides compositions and methods for inhibiting Chk1 and/or Chk2 kinases. Also provided are compositions and methods for inhibiting G2 cell arrest checkpoint, particularly in mammalian, e.g., human, cells. The compositions and methods of the invention are also used to treat disorders of cell growth, such as cancer. In particular, the invention provides methods for selectively sensitizing G1 checkpoint impaired cancer cells to DNA damaging agents and treatments. Also provided are methods for screening for compounds able to interact with, e.g., inhibit, enzymes involved in the G2 cell cycle arrest checkpoint, such as Chk1 and/or Chk2/Cds1 kinase.

Abstract translation: 本发明提供了用于抑制Chk1和/或Chk2激酶的组合物和方法。 还提供了用于抑制G2细胞停滞检查点的组合物和方法，特别是在哺乳动物例如人的细胞中。 本发明的组合物和方法也用于治疗诸如癌症的细胞生长障碍。 特别地，本发明提供了选择性地使G1检查点受损的癌细胞对DNA损伤剂和治疗敏感的方法。 还提供了筛选能够与例如Chk1和/或Chk2 / Cds1激酶参与的G2细胞周期停滞检查点相关的化合物例如抑制化合物的方法。

公开(公告)号：WO2010035631A8

公开(公告)日：2010-06-10

申请号：PCT/JP2009065614

申请日：2009-09-02

Applicant: NISSEI PLASTICS IND CO ,  ART METAL MFG CO LTD ,  SATO TOMOYUKI ,  SUGANUMA MASASHI ,  KARASAWA TOMONORI ,  KANAI SHOJI ,  MATSUMOTO AKIRA

Inventor： SATO TOMOYUKI ,  SUGANUMA MASASHI ,  KARASAWA TOMONORI ,  KANAI SHOJI ,  MATSUMOTO AKIRA

IPC: F02F3/10 ,  C25D15/00 ,  F02F7/00

CPC classification number: C25D15/00 ,  C25D3/20 ,  C25D15/02 ,  F02F3/10 ,  F02F7/0085 ,  F05C2201/021 ,  F05C2201/0436 ,  F05C2203/0808 ,  F05C2251/048 ,  F05C2251/10 ,  F05C2253/04 ,  Y10T428/12757

Abstract: A technique for using an iron plating for coating an aluminum product that results in adequate durability. An aluminum piston (l?) used as a plated aluminum product is covered by an iron-based composite plating layer (l l). The iron-based composite plating layer (ll) contains a carbon nanomaterial, which is applied to the aluminum-based base material using a iron-based composite plating bath formed by mixing a carbon nanomaterial into an iron plating bath.

Abstract translation: 一种使用铁镀层涂覆铝制品的技术，可以产生足够的耐久性。 用作镀铝产品的铝活塞（1“）被铁基复合镀层（11）覆盖。 铁基复合镀层（11）含有碳纳米材料，该碳纳米材料使用通过将碳纳米材料混合到铁镀浴中形成的铁基复合镀浴而涂覆到铝基基材上。