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    Compounds for the reduction of the deleterious activity of extended nucleotide repeat containing genes
    1.
    发明专利
    Compounds for the reduction of the deleterious activity of extended nucleotide repeat containing genes 未知

    公开(公告)号：IL271595D0

    公开(公告)日：2020-02-27

    申请号：IL27159519

    申请日：2019-12-19

    Applicant: UNIV LELAND STANFORD JUNIOR ,  SUN THOMAS W

    Inventor： SUN THOMAS W

    IPC: A61P20060101

    Abstract: Aspects of the present disclosure include methods of reducing the deleterious impact of a target gene in a cell, such as the deleterious activity of a mutant extended nucleotide repeat (NR) containing target gene in a cell by contacting the cell with an effective amount of a tetrahydrocarbazolamine compound. The deleterious activity (e.g., toxicity and/or dis-functionality of products encoded thereby) of a mutant extended NR containing target gene may be reduced, e.g., by reducing (and in some instances differentially, including selectively, reducing) the production or activity of toxic expression products (e.g., RNA or protein) encoded by the target gene. Kits and compositions for practicing the subject methods are also provided.

    METHOD AND APPARATUS FOR DATA QUANTIZATION AND PACKING WITH VARIABLE BIT WIDTH AND PERIOD
    5.
    发明申请
    METHOD AND APPARATUS FOR DATA QUANTIZATION AND PACKING WITH VARIABLE BIT WIDTH AND PERIOD 审中-公开
    用于数据量化和包装的可变位宽度和周期的方法和装置

    公开(公告)号：WO2012148601A1

    公开(公告)日：2012-11-01

    申请号：PCT/US2012/030197

    申请日：2012-03-22

    Applicant: QUALCOMM INCORPORATED ,  OH, Seokyong ,  SUN, Thomas ,  KRISHNAMOORTHI, Raghuraman

    Inventor： OH, Seokyong ,  SUN, Thomas ,  KRISHNAMOORTHI, Raghuraman

    IPC: H04L25/06 ,  H04L25/03

    CPC classification number: H04L25/03184 ,  H04L25/067

    Abstract: The various embodiments provide circuitry and methods for packing Log Likelihood Ratio ("LLR") values into a buffer memory in a compressed format which reduces the amount of buffer memory required. Various embodiments use a type of quantization which reduces the bit width of the LLR values that are stored, with the particular level of quantization depending upon the code rate of the data. The degree, pattern, and periodicity of bit width compression employed may depend upon the code rate of the received transmission. Bit width patterns use for LLR value quantization may be generated by a shift register circuit which provides an efficient mechanism for controlling an LLR packer circuit based upon the code rate of the received signal.

    Abstract translation: 各种实施例提供用于将对数似然比（“LLR”）值以压缩格式打包到缓冲存储器中的电路和方法，其减少所需的缓冲存储器的量。 各种实施例使用一种类型的量化，其根据数据的码率降低具有特定的量化水平的存储的LLR值的位宽度。 所采用的位宽度压缩的程度，模式和周期可能取决于接收到的传输的码率。 用于LLR值量化的位宽度图案可以由移位寄存器电路产生，该移位寄存器电路基于接收信号的码率提供用于控制LLR封隔器电路的有效机构。

    SCHEDULING DATA WITH TIME DIVERSITY IN FLO SYSTEMS
    8.
    发明申请
    SCHEDULING DATA WITH TIME DIVERSITY IN FLO SYSTEMS 审中-公开
    在FLO系统中调度数据与时间多样性

    公开(公告)号：WO2010059772A1

    公开(公告)日：2010-05-27

    申请号：PCT/US2009/065059

    申请日：2009-11-19

    Applicant: QUALCOMM Incorporated ,  SUN, Thomas ,  LING, Fuyun ,  JIANG, Jing ,  KRISHNAMOORTHI, Raghuraman ,  TIAN, Tao ,  WALKER, Kent

    Inventor： SUN, Thomas ,  LING, Fuyun ,  JIANG, Jing ,  KRISHNAMOORTHI, Raghuraman ,  TIAN, Tao ,  WALKER, Kent

    IPC: H04L1/00 ,  H03M13/29

    CPC classification number: H04L1/0071 ,  H03M13/27 ,  H03M13/2957 ,  H04L1/0041 ,  H04L2001/0098

    Abstract: Methods and systems are described for scheduling data in an FLO system. The method may include turbo encoding the data, and dividing a packet of the turbo-coded data into a plurality of subpackets. The method may include scheduling the turbo-coded packet of data so as to distribute the data across multiple frames of a superframe, by transmitting each one of the subpackets during a different frame of the superframe to increase time diversity. The turbo-coded packet of data may comprise systematic bits and parity bits. The method may include separately scheduling the systematic bits and the parity bits during different frames of the superframe.

    Abstract translation: 描述了用于在FLO系统中调度数据的方法和系统。 该方法可以包括对数据进行turbo编码，并将turbo编码数据的分组划分成多个子分组。 该方法可以包括通过在超帧的不同帧期间发送每个子分组以增加时间分集来调度数据的turbo编码分组以便分布跨超帧的多个帧的数据。 turbo编码的数据分组可以包括系统比特和奇偶校验比特。 该方法可以包括在超帧的不同帧期间单独调度系统比特和奇偶校验比特。

    BUFFERING OF METRIC DATA
    10.
    发明申请
    BUFFERING OF METRIC DATA 审中-公开

    公开(公告)号：WO2007115313A3

    公开(公告)日：2007-10-11

    申请号：PCT/US2007/065985

    申请日：2007-04-04

    Applicant: QUALCOMM Incorporated ,  BAI, Jinxia ,  GANAPATHY, Chinnappa, K. ,  SUN, Thomas

    Inventor： BAI, Jinxia ,  GANAPATHY, Chinnappa, K. ,  SUN, Thomas

    IPC: H04N5/00

    Abstract: Methods and apparatus for dynamic packet mapping. A method is provided for mapping metric data to produce a decodable packet associated with a channel. The method includes obtaining a channel identifier associated with metric data, determining an available buffer from a plurality of buffers based on the channel identifier, writing the metric data to the available buffer, detecting when a decodable packet is formed in a selected buffer of the plurality of buffers, and outputting the decodable packet from the selected buffer. An apparatus includes a plurality of buffers and mapping logic that is configured to obtain a channel identifier associated with metric data, determine an available buffer based on the channel identifier, write the metric data to the available buffer, detect when a decodable packet is formed in a selected buffer, and output the decodable packet from the selected buffer.

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