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1.
公开(公告)号:US20050237480A1
公开(公告)日:2005-10-27
申请号:US10511788
申请日:2003-05-13
Applicant: Nancy Allbritton , Christopher Sims , Guann-Pyng Li , Mark Bachman , Shuwen Hu , Xueqin Ren
Inventor: Nancy Allbritton , Christopher Sims , Guann-Pyng Li , Mark Bachman , Shuwen Hu , Xueqin Ren
IPC: C08J7/18 , G01N27/447 , G02B1/04 , G02C7/04
CPC classification number: C08J7/18 , B01J2219/00605 , B01J2219/0061 , B01J2219/0063 , B01J2219/00635 , B01J2219/00637 , G01N27/44704 , G01N27/44752 , G02B1/043
Abstract: Polymer-based biomaterials are popular due to ease of fabrication and low costs. However, many polymer substrates have undesirable surface properties. The invention provides a procedure to covalently apply a graft polymer to the surface of a polymer substrate by ultraviolet graft polymerization. The graft polymer is formed from monomers such as PEG, AA, monomethoxy acrylate PEG, HEMA, or DMA. Also, mixed monomers may be used to create the graft and the surface properties of the graft may be tailored for different properties, including hydrophobicity, friction coefficient, electroosmotic mobilities and electrophoretic separations. The invention has particular utility in tailoring surface chemistries in ocular lenses and polymer microdevices. I. II. R:—OHAcrylic Acid(AA) —NH2Acrylamide (AM) —N(CH3)2Dimethylacrylamide (DMA) —OCH2CH2OH2-Hydroxyethylacrylate (HEA) —O(CH2CH2O)nCH3PEG monomethyoxylacrylate (PEG)
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