公开(公告)号：US06670407B2

公开(公告)日：2003-12-30

申请号：US10164580

申请日：2002-06-10

Applicant: Steven Melvyn Howdle ,  Vladimir Popov

Inventor： Steven Melvyn Howdle ,  Vladimir Popov

IPC: C08K300

CPC classification number: B05D3/0446 ,  A61K6/033 ,  A61K6/08 ,  A61K6/083 ,  A61K6/087 ,  A61K9/1694 ,  A61L27/44 ,  A61L27/50 ,  B05D7/02 ,  B05D2401/90

Abstract: Process for the preparation of a composition comprising a biofunctional polymer substrate and biofunctional material substrate adapted for use in or in association with the human or animal body, cultivated or uncultivated living matter, wherein the biofunctional material substrate is substantially insoluble in the polymer substrate and/or a supercritical fluid, wherein the process comprises contacting a mixture of the substrates or their precursors with a supercritical fluid under supercritical conditions and conditions of reduced viscosity and physical blending to plasticise and swell the polymer and distribute the biofunctional material substrate throughout the polymer, and releasing the fluid under subcritical conditions, wherein the substrates are adapted to be isolated in form of a solid admixture comprising the biofunctional material substrate in substantially unchanged chemical form, and in substantially unchanged physical form, composition obtained thereby, polymer matrix embodiment thereof and the process for its preparation.

公开(公告)号：US06414050B1

公开(公告)日：2002-07-02

申请号：US09423306

申请日：2000-01-10

Applicant: Steven Melvyn Howdle ,  Vladimir Popov

Inventor： Steven Melvyn Howdle ,  Vladimir Popov

IPC: C08K300

CPC classification number: B05D3/0446 ,  A61K6/033 ,  A61K6/08 ,  A61K6/083 ,  A61K6/087 ,  A61K9/1694 ,  A61L27/44 ,  A61L27/50 ,  B05D7/02 ,  B05D2401/90

Abstract: Compositions comprising an admixture of a biofunctional polymer substrate and a biofunctional material substrate adapted for use in or in association with the human or animal body, cultivated or uncultivated living matter and methods for making and using thereof are disclosed. The biofunctional material substrate retains bioactivity in the admixture. As disclosed, the compositions may be made by a process which comprises contacting a mixture of the substrates or their precursors with a supercritical fluid under supercritical conditions of reduced viscosity to plasticise and swell the biofunctional polymer substrate and under conditions of physical blending to distribute the biofunctional material substrate throughout the biofunctional polymer substrate, and releasing the supercritical fluid under subcritical conditions. Also disclosed are biofunctional polymer matrices and methods of making and using thereof.

Abstract translation: 公开了包含生物功能性聚合物底物和适于在人体或动物体中使用或与人体或动物体结合使用的生物功能性材料底物的混合物的组合物，培养或未培养的生物及其制备和使用方法。 生物功能材料底物在混合物中保留生物活性。 如所公开的，组合物可以通过以下方法制备：包括将底物或其前体的混合物与超临界流体在较低粘度的超临界条件下接触以使生物功能性聚合物底物膨胀并溶胀并在物理共混条件下分配生物官能 在整个生物功能性聚合物基材上的材料基材，以及在亚临界条件下释放超临界流体。 还公开了生物功能性聚合物基质及其制备和使用方法。

公开(公告)号：US08268394B2

公开(公告)日：2012-09-18

申请号：US10595323

申请日：2004-10-08

Applicant: Pier John Anthony Sazio ,  John Victor Badding ,  Dan William Hewak ,  Steven Melvyn Howdle

Inventor： Pier John Anthony Sazio ,  John Victor Badding ,  Dan William Hewak ,  Steven Melvyn Howdle

IPC: B05D5/00 ,  B05D5/06 ,  B05D7/22 ,  B05D3/02 ,  B05D3/06 ,  H01L21/36 ,  H01L21/00

CPC classification number: G02B6/02385 ,  C03B19/00 ,  C03B37/0122 ,  C03B2201/58 ,  C03B2203/42 ,  C03C13/04 ,  C03C25/104 ,  G02B1/007 ,  G02B6/0229 ,  G02B6/02352 ,  G02B6/02357 ,  G02B6/02371 ,  G02B6/0238

Abstract: A method of fabricating a metamaterial is provided, comprising providing a sample of engineered microstructured material that is transparent to electromagnetic radiation and comprises one or more voids, passing through the voids a high pressure fluid comprising a functional material carried in a carrier fluid, and causing the functional material to deposit or otherwise integrate into the engineered microstructured material to form the metamaterial. Many microstructured materials and functional materials can be used, together with various techniques for controlling the location of the integration of the functional material within the microstructured material, so that a wide range of different metamaterials can be produced.

Abstract translation: 提供了一种制造超材料的方法，包括提供对电磁辐射透明的工程化微结构材料的样品，并且包括一个或多个空隙，通过空隙将包含承载在载体流体中的功能材料的高压流体引入， 功能材料沉积或以其他方式整合到工程化微结构材料中以形成超材料。 可以使用许多微结构材料和功能材料，以及用于控制功能材料在微结构材料内的整合位置的各种技术，从而可以产生宽范围的不同的超材料。

公开(公告)号：US06593439B1

公开(公告)日：2003-07-15

申请号：US09719987

申请日：2001-03-06

Applicant: Paul Christian ,  Steven Melvyn Howdle ,  Derek John Irvine

Inventor： Paul Christian ,  Steven Melvyn Howdle ,  Derek John Irvine

IPC: C08F1820

CPC classification number: C08F2/06 ,  Y02P20/544

Abstract: A method of producing a polymer comprises the steps of forming a heterogeneous reaction mixture comprising at least one addition polymerizable monomer, a supercritical fluid, and a stabilizer, wherein the stabilizer comprises a chain which is soluble in the supercritical fluid and functional end-group which is not polymerizable by a free-radical mechanism, and polymerizing said at least one monomer in the reaction mixture. In a preferred system for polymerizing acrylic monomers, the fluid comprises supercritical carbon dioxide and the stabilizer comprises an acid-functionalized perfluoropolyether.

Abstract translation: 制备聚合物的方法包括以下步骤：形成包含至少一种可加成聚合单体，超临界流体和稳定剂的非均相反应混合物，其中稳定剂包括可溶于超临界流体和功能性末端基团的链， 不能通过自由基机理聚合，并且在反应混合物中聚合所述至少一种单体。 在用于聚合丙烯酸单体的优选体系中，流体包含超临界二氧化碳，并且稳定剂包含酸官能化的全氟聚醚。