APPARATUS AND METHODS FOR CONTROLLING ORGAN TEMPERATURE PRIOR TO AND/OR DURING TRANSPLANTATION PROCEDURES

    公开(公告)号:US20240023541A1

    公开(公告)日:2024-01-25

    申请号:US18029316

    申请日:2021-09-29

    CPC classification number: A01N1/021 A01N1/0247 A01N1/0252 A01N1/0284

    Abstract: The invention discloses a temperature control, optionally cooling, apparatus comprising: a first and second and/or plurality of fillable chambers each having a first layer, a second layer, an elongated edge, preferably longitudinal edge, an inlet and an outlet in the elongated, preferably longitudinal edge, and retention members between the first layer and second layer in a series of spaced veins creating a continuous channel extending from the inlet to the outlet; and a method of cooling and or maintaining an organ comprising: a method for cooling, warming and/or maintaining the temperature of an organ prior to or during a transplant procedure, the method comprising: contacting the organ with temperature control, optionally the cooling and/or temperature maintaining, apparatus; securing the apparatus to the organ; attaching the inlets of the first and second and/or plurality of fillable chambers of the apparatus to a circulation fluid source; and/or infusing circulation fluid into the inlet, through the continuous channel, and out the outlet of each of the first and second and/or plurality of fillable chambers of the apparatus.

    DIELECTRIC STRAP WAVEGUIDES, ANTENNAS, AND MICROWAVE DEVICES
    2.
    发明申请
    DIELECTRIC STRAP WAVEGUIDES, ANTENNAS, AND MICROWAVE DEVICES 审中-公开
    电介质波导波导,天线和微波器件

    公开(公告)号:US20150303546A1

    公开(公告)日:2015-10-22

    申请号:US14410369

    申请日:2013-06-21

    Abstract: A new class of antennas and microwave components are introduced. In this approach a high-permittivity dielectric film is applied (i.e. printed) on a dielectric substrate, which may be grounded. By changing the shape of the high-permittivity film, different microwave devices (e.g. waveguides, filters, couplers, and antennas) are produced. By changing the size and permittivity of the high-permittivity film and dielectric substrate, these elements are designed at different frequencies for different applications. Highly-efficient microwave devices can result due to the absence of surface currents.

    Abstract translation: 引入了一类新型的天线和微波元件。 在这种方法中,将高介电常数介质膜施加(即印刷)在可以接地的电介质基板上。 通过改变高介电常数膜的形状,产生不同的微波器件(例如波导,滤波器,耦合器和天线)。 通过改变高介电常数薄膜和电介质基片的尺寸和介电常数,这些元件在不同的应用中被设计在不同的频率上。 由于没有表面电流,可以产生高效的微波器件。

    APPARATUS AND METHODS FOR CONTROLLING ORGAN TEMPERATURE PRIOR TO AND/OR DURING TRANSPLANTATION PROCEDURES

    公开(公告)号:WO2022067429A1

    公开(公告)日:2022-04-07

    申请号:PCT/CA2021/051355

    申请日:2021-09-29

    Abstract: The invention discloses a temperature control, optionally cooling, apparatus comprising: a first and second and/or plurality of fillable chambers each having a first layer, a second layer, an elongated edge, preferably longitudinal edge, an inlet and an outlet in the elongated, preferably longitudinal edge, and retention members between the first layer and second layer in a series of spaced veins creating a continuous channel extending from the inlet to the outlet; and a method of cooling and or maintaining an organ comprising: a method for cooling, warming and/or maintaining the temperature of an organ prior to or during a transplant procedure, the method comprising: contacting the organ with temperature control, optionally the cooling and/or temperature maintaining, apparatus; securing the apparatus to the organ; attaching the inlets of the first and second and/or plurality of fillable chambers of the apparatus to a circulation fluid source; and/or infusing circulation fluid into the inlet, through the continuous channel, and out the outlet of each of the first and second and/or plurality of fillable chambers of the apparatus.

    SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME
    4.
    发明申请
    SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME 审中-公开
    具有中枢神经系统活性的半胱氨酸和含有其的药物制剂

    公开(公告)号:WO1996040628A1

    公开(公告)日:1996-12-19

    申请号:PCT/CA1996000380

    申请日:1996-06-07

    CPC classification number: C07C281/14

    Abstract: A compound of general formula (I) useful as an anticonvulsant for disorders of the central nervous system wherein: R , R , R and R may be the same or different and each represents a hydrogen or halogen atom, or a C1-9alkyl, C3-9cycloalkyl, cyano, C1-9alkoxy or C6-10aryloxy group; R represents a hydrogen atom or a C1-9alkyl, C3-9cycloalkyl or C6-10aryl group; and X is oxygen or sulfur; or a pharmaceutically-acceptable salt thereof. The compound may be administered orally for treating convulsions in humans or animals.

    Abstract translation: 用作中枢神经系统障碍的抗惊厥药的通式(I)化合物,其中:R 1,R 2,R 3和R 4可以相同或不同,并且各自表示 氢或卤原子,或C1-9烷基,C3-9环烷基,氰基,C1-9烷氧基或C6-10芳氧基; R 5表示氢原子或C 1-8烷基,C 3-9环烷基或C 6-10芳基; X为氧或硫; 或其药学上可接受的盐。 该化合物可以口服给药以治疗人或动物的抽搐。

    PORCINE ADENOVIRUS E1 AND E4 REGIONS
    8.
    发明公开
    PORCINE ADENOVIRUS E1 AND E4 REGIONS 审中-公开
    E1 E4和猪腺病毒区

    公开(公告)号:EP1430137A2

    公开(公告)日:2004-06-23

    申请号:EP02799137.1

    申请日:2002-09-24

    Abstract: The present invention relates to the characterization of the porcine adenovirus E1 and E4 regions. The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3), providing the characterization of the PAV3 E1 and E4 region, is described herein. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals.

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