公开(公告)号：IL219694A

公开(公告)日：2017-09-28

申请号：IL21969412

申请日：2012-05-09

Applicant: EVONIK DEGUSSA GMBH ,  OLIVIER ZEHNACKER ,  THOMAS TACKE ,  THOMAS HAAS ,  NICOLE BRAUSCH ,  MARC BECKER

Inventor： OLIVIER ZEHNACKER ,  THOMAS TACKE ,  THOMAS HAAS ,  NICOLE BRAUSCH ,  MARC BECKER

IPC: A23L27/00 ,  A23L27/30 ,  C07H20060101 ,  C13K20060101

Abstract: A sweetener and to a method of production thereof is provided. The task of the present invention consists of providing a sucrose-based sweetener, in the production of which the step of separation of the residual sucrose from the isomerization stage is not required, and which has excellent properties for further processing, for example it can be formulated as sweets.

公开(公告)号：IL219694D0

公开(公告)日：2012-07-31

申请号：IL21969412

申请日：2012-05-09

Applicant: EVONIK DEGUSSA GMBH ,  OLIVIER ZEHNACKER ,  THOMAS TACKE ,  THOMAS HAAS ,  NICOLE BRAUSCH ,  MARC BECKER

IPC: A23L27/00 ,  A23L27/30 ,  C07H20060101

Abstract: A sweetener and to a method of production thereof is provided. The task of the present invention consists of providing a sucrose-based sweetener, in the production of which the step of separation of the residual sucrose from the isomerization stage is not required, and which has excellent properties for further processing, for example it can be formulated as sweets.

公开(公告)号：US10450590B2

公开(公告)日：2019-10-22

申请号：US14763378

申请日：2014-01-10

Applicant: Thomas Haas ,  Philip Engel ,  Jan Christoph Pfeffer ,  Oliver Thum ,  Christian Gehring

Inventor： Thomas Haas ,  Philip Engel ,  Jan Christoph Pfeffer ,  Oliver Thum ,  Christian Gehring

IPC: C12P7/18 ,  C07C67/08 ,  C07C29/136 ,  C12P7/62

Abstract: The invention relates to a process for preparing an α,ω-alkanediol comprising the steps of a) reacting an alkanoic acid with an alkanol to give an ester, b) oxidizing at least one terminal carbon atom of the ester by contacting with a whole-cell catalyst, which expresses an alkane hydroxylase, in aqueous solution and in the presence of molecular oxygen, to give an oxidized ester, c) hydrogenating the oxidized ester to form the alkanediol and alkanol, and d) removing the alkanol by distillation, forming a reaction mixture depleted with respect to the alkanol, and recycling the alkanol in step b).

公开(公告)号：US20180142266A1

公开(公告)日：2018-05-24

申请号：US15579442

申请日：2016-06-10

Applicant: Thomas Haas ,  Anja Hecker ,  Stefan Gilch ,  Thomas Bülter

Inventor： Thomas Haas ,  Anja Hecker ,  Stefan Gilch ,  Thomas Bülter

IPC: C12P7/04 ,  C12N9/02 ,  C12N9/04 ,  C12P7/16

CPC classification number: C12P7/04 ,  C12N9/0006 ,  C12N9/0008 ,  C12N15/52 ,  C12P7/16 ,  C12P7/40 ,  C12P7/62 ,  C12Y101/01001 ,  C12Y102/0101 ,  Y02E50/10

Abstract: There is provided a microbial cell which is capable of producing at least one higher alcohol, wherein the microbial cell is genetically modified to include an increased expression relative to its wild type cell of at least one acyl-CoA reductase (E11). In particular, there is provided a microbial cell capable of producing at least one higher alcohol, wherein the microbial cell is genetically modified to include an increased expression relative to its wild type cell of at least one acyl-CoA reductase (E11) and wherein the cell is capable of producing a carboxylic acid and/or ester thereof using ethanol-carboxylate fermentation.

公开(公告)号：US20160244790A1

公开(公告)日：2016-08-25

申请号：US15073105

申请日：2016-03-17

Applicant: Thomas HAAS ,  Jan Christoph Pfeffer ,  Kurt Faber ,  Michael Fuchs

Inventor： Thomas HAAS ,  Jan Christoph Pfeffer ,  Kurt Faber ,  Michael Fuchs

IPC: C12P13/00 ,  C12P17/04 ,  C12P7/22 ,  C12P17/12

CPC classification number: C12P13/001 ,  C12P7/22 ,  C12P17/04 ,  C12P17/12

Abstract: A method comprising the steps (a) contacting a hydrocarbon comprising a hydroxyl group with a biological agent having oxygen-dependent and cofactor-dependent carbohydrate oxidase activity in the presence of oxygen and carbohydrate oxidase cofactor, and (b) contacting the hydrocarbon produced in step a) with a biological agent having transaminase activity and a biological agent having cofactor-dependent amino acid dehydrogenase activity in the presence of amino acid dehydrogenase cofactor and the substrate amino acid of the amino acid dehydrogenase.

Abstract translation: 一种方法，包括以下步骤：（a）在氧和碳水化合物氧化酶辅因子的存在下使包含羟基的烃与具有氧依赖性和辅因子依赖性碳水化合物氧化酶活性的生物试剂接触，和（b）使步骤 a）具有转氨酶活性的生物制剂和在氨基酸脱氢酶辅因子和氨基酸脱氢酶的底物氨基酸存在下具有辅因子依赖性氨基酸脱氢酶活性的生物试剂。

公开(公告)号：US20160215302A1

公开(公告)日：2016-07-28

申请号：US15009425

申请日：2016-01-28

Applicant: Thomas HAAS ,  Thomas BUELTER ,  Martin DEMLER

Inventor： Thomas HAAS ,  Thomas BUELTER ,  Martin DEMLER

IPC: C12P7/04 ,  C12N1/20

Abstract: The present invention relates to a reaction mixture and a method of producing at least one higher alcohol comprising a reaction mixture comprising a mixed culture of a first and a second microorganism in an aqueous medium comprising carbon monoxide gas, wherein the first microorganism is an acetogenic microorganism capable of converting a carbon source to acetate and/or ethanol; and the second microorganism is selected from the group consisting of Clostridium kluyveri, and C. Carboxidivorans capable of converting the acetate and/or ethanol to form an acid; wherein the first microorganism is further capable of converting the acid to the corresponding higher alcohol and the higher alcohol comprises at least 6 carbon atoms.

Abstract translation: 本发明涉及一种反应混合物和一种生产至少一种高级醇的方法，所述高级醇包括在包含一氧化碳气体的水性介质中包含第​​一和第二微生物的混合培养物的反应混合物，其中第一微生物是产乙酸微生物 能够将碳源转化成乙酸酯和/或乙醇; 并且第二微生物选自克氏梭菌（Clostridium kluyveri）和C.能够转化乙酸盐和/或乙醇以形成酸的羧酰替葡萄糖; 其中第一微生物还能够将酸转化成相应的高级醇，高级醇包含至少6个碳原子。

公开(公告)号：US20160177259A1

公开(公告)日：2016-06-23

申请号：US14969891

申请日：2015-12-15

Applicant: Thomas HAAS ,  Thomas BUELTER ,  Martin DEMLER ,  Anja THIESSENHUSEN

Inventor： Thomas HAAS ,  Thomas BUELTER ,  Martin DEMLER ,  Anja THIESSENHUSEN

IPC: C12N1/20 ,  C12P7/24 ,  C12P7/06

CPC classification number: C12N1/20 ,  C12P7/065 ,  C12P7/24 ,  C12P7/54 ,  Y02E50/17

Abstract: A method of culturing at least one acetogenic bacteria, includes growing the bacteria in an aqueous medium comprising an amount of cysteine and/or cystine, wherein the cysteine and/or cystine concentration in the medium is maintained at a concentration of less than 0.20 g/L.

Abstract translation: 培养至少一种致生菌的方法包括在包含一定量的半胱氨酸和/或胱氨酸的水性介质中培养细菌，其中培养基中的半胱氨酸和/或胱氨酸浓度保持在小于0.20g / L.

公开(公告)号：US20160138061A1

公开(公告)日：2016-05-19

申请号：US14943333

申请日：2015-11-17

Applicant: Thomas HAAS ,  Markus Poetter ,  Steffen Schaffer

Inventor： Thomas HAAS ,  Markus Poetter ,  Steffen Schaffer

IPC: C12P7/64

CPC classification number: C12P7/6409 ,  Y02P20/59

Abstract: At least one fatty acid and/or derivative thereof is produced from a gas containing H2, CO2, and O2 by providing a genetically modified hydrogen oxidizing bacterium in an aqueous medium; and contacting the aqueous medium with the gas containing H2, CO2 and O2 in a weight ratio of 20 to 70 (H2): 10 to 45 (CO2): 5 to 35 (O2); wherein the fatty acid contains at least 5 carbon atoms and wherein the hydrogen oxidizing bacterium is genetically modified relative to the wild type bacterium to increase the expression of enzyme E1 that is capable of catalyzing the conversion of acetyl CoA to acyl ACP via malonyl coA and to increase the expression of enzyme E2 that is capable of catalyzing the conversion of Acyl ACP to the fatty acid.

Abstract translation: 通过在水性介质中提供遗传修饰的氢氧化细菌，从含有H 2，CO 2和O 2的气体产生至少一种脂肪酸和/或其衍生物; 并使含水介质与含有H 2，CO 2和O 2的气体以20至70（H 2）：10至45（CO 2）：5至35（O 2）的重量比接触; 其中所述脂肪酸含有至少5个碳原子，并且其中所述氢氧化细菌相对于野生型细菌被遗传修饰以增加能够通过丙二酰辅酶A催化乙酰辅酶A转化为酰基ACP的酶E1的表达， 增加能够催化酰基ACP向脂肪酸转化的酶E2的表达。

公开(公告)号：US09150890B2

公开(公告)日：2015-10-06

申请号：US14609714

申请日：2015-01-30

Applicant: Markus Poetter ,  Hans-Georg Hennemann ,  Steffen Schaffer ,  Thomas Haas

Inventor： Markus Poetter ,  Hans-Georg Hennemann ,  Steffen Schaffer ,  Thomas Haas

IPC: C12P7/62 ,  C12N1/16 ,  C12N9/02 ,  C12P7/42 ,  C12P13/04 ,  C07C51/347 ,  C07C67/42 ,  C07C227/06 ,  C07C227/08

CPC classification number: C12P7/62 ,  C07C51/347 ,  C07C67/42 ,  C07C227/06 ,  C07C227/08 ,  C12N1/16 ,  C12N9/004 ,  C12N9/0042 ,  C12P7/42 ,  C12P7/625 ,  C12P13/04 ,  C12Y101/01001

Abstract: The invention relates to genetically engineered Candida tropicalis cells, use thereof and a method of production of ω-hydroxycarboxylic acids and ω-hydroxycarboxylic acid esters.

公开(公告)号：US09108473B2

公开(公告)日：2015-08-18

申请号：US12675910

申请日：2008-08-21

Applicant: Thomas Haas ,  Gregor Kuchler

Inventor： Thomas Haas ,  Gregor Kuchler

IPC: B60C23/00 ,  B60C23/04

CPC classification number: B60C23/041 ,  B60C23/0462

Abstract: A method for operating wheel electronics of a tire checking system includes providing wheel electronics having a battery-free power supply encompassing at least one rechargeable power storage medium for supplying power to the wheel electronics. The wheel electronics can be operated in a reduced-power transmission mode and a subsequent normal transmission mode. In the modes, data that relate to tire-specific parameters and are determined by the wheel electronics are transmitted to a vehicle-mounted communication device in the form of modulated transmission signals, with less transmission power being used for the transmission signals in the power-reduced transmission mode than in the normal transmission mode. Wheel electronics and a tire checking system are also provided.

Abstract translation: 一种用于操作轮胎检查系统的轮子电子装置的方法包括提供具有无电池电源的车轮电子装置，其包含用于向车轮电子装置供电的至少一个可再充电电力存储介质。 车轮电子装置可以在低功率传输模式和随后的正常传输模式下工作。 在这些模式中，与轮胎特定参数相关并且由车轮电子装置确定的数据以调制传输信号的形式发送到车载通信装置，其中较少的发射功率被用于功率传输信号中的传输信号， 传输模式比正常传输模式低。 还提供车轮电子和轮胎检查系统。