中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

32 records (took 0.03 seconds)

    METHODS AND APPARATUS FOR MOLECULAR DATA STORAGE, RETRIEVAL AND ANALYSIS
    3.
    发明申请
    METHODS AND APPARATUS FOR MOLECULAR DATA STORAGE, RETRIEVAL AND ANALYSIS 审中-公开
    用于分子数据存储，检索和分析的方法和装置

    公开(公告)号：WO2003089666A2

    公开(公告)日：2003-10-30

    申请号：PCT/CA2003/000574

    申请日：2003-04-17

    Applicant: UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. ,  LEE, Jeremy, S. ,  WETTIG, Shawn, D. ,  KRAATZ, Heinz-Bernhard

    Inventor： LEE, Jeremy, S. ,  WETTIG, Shawn, D. ,  KRAATZ, Heinz-Bernhard

    IPC: C12Q1/68

    CPC classification number: G01N33/48721 ,  B82Y10/00 ,  C12Q1/6825 ,  C12Q1/6827 ,  G11C13/0014 ,  G11C13/0019 ,  H01L51/0093 ,  H01L51/0595 ,  C12Q2565/629 ,  C12Q2565/631 ,  C12Q2563/137

    Abstract: In various aspects, the invention provides molecular systems for storing and retrieving information. In some embodiments, polymers capable of selectively binding metal ions, such as nucleic acids, are used to record information in the form of a particular molecular conformation. Electrochemical assay methods employing nanopores may be used to read and write information using such polymeric media. In some embodiments, information may be recorded in a nucleic acid polymer by magnetically modulating the translocation of the nucleic acid through a channel in a medium, while simultaneously modulating the electrostatic potential across the channel. In this way, the incorporation of a divalent metal ion in the nucleic acid duplex may be modulated to store information. In an alternative aspect, the invention provides analogous processes for detecting a base pair mismatch in a nucleic acid polymer.

    Abstract translation: 在各个方面，本发明提供用于存储和检索信息的分子系统。 在一些实施方案中，能够选择性地结合金属离子（例如核酸）的聚合物用于以特定分子构象的形式记录信息。 使用纳米孔的电化学测定方法可用于使用这种聚合物介质读取和写入信息。 在一些实施方案中，可以通过磁性调节核酸通过介质中的通道的易位，同时同时调节跨过该通道的静电势来将信息记录在核酸聚合物中。 以这种方式，可以调节在核酸双链体中引入二价金属离子以存储信息。 在另一方面，本发明提供用于检测核酸聚合物中碱基对错配的类似方法。

    NUCLEIC ACID CIRCUIT ELEMENTS AND METHODS
    5.
    发明申请
    NUCLEIC ACID CIRCUIT ELEMENTS AND METHODS 审中-公开
    核酸电路元件和方法

    公开(公告)号：WO2002095840A1

    公开(公告)日：2002-11-28

    申请号：PCT/CA2002/000769

    申请日：2002-05-24

    Applicant: UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. ,  LEE, Jeremy, Stuart ,  SKINNER, Ryan, John, Jr.

    Inventor： LEE, Jeremy, Stuart ,  SKINNER, Ryan, John, Jr.

    IPC: H01L51/20

    CPC classification number: H01L51/0595 ,  B82Y10/00 ,  G11C13/0014 ,  G11C13/0019 ,  H01L51/0077 ,  H01L51/0093

    Abstract: Organic circuit elements and methods are disclosed. An organic circuit element includes a plurality of members, each of which includes an oligonucleotide duplex. The plurality of members includes at least one donor member for receiving conduction electrons from an electron donor, at least one acceptor member for communicating with an electron acceptor to provide a region of attraction for the conduction electrons, and at least one regulator member intersecting with at least one of the plurality of members to define at least one electric field regulation junction, for cooperating with an electric field regulator to regulate an electric field at the junction. A method of regulating an electronic signal between first and second locations in a conductive nucleic acid material includes varying an electrostatic potential at a third location in the nucleic acid material interposed between the first and second locations. The third location may include the regulation junction.

    Abstract translation: 公开了有机电路元件和方法。 有机电路元件包括多个构件，每个构件包括寡核苷酸双链体。 多个构件包括用于从电子给体接收传导电子的至少一个施主构件，用于与电子受体连通以提供导电电子的吸引区域的至少一个受体构件，以及与传导电子相交的至少一个调节构件 所述多个构件中的至少一个构件限定至少一个电场调节结，用于与电场调节器配合以调节所述接合处的电场。 调节导电核酸材料中第一和第二位置之间的电子信号的方法包括改变介于第一和第二位置之间的核酸材料中的第三位置处的静电电位。 第三个位置可能包括调节接头。

    PLANT STRESS TOLERANCE GENES, AND USES THEREFOR
    8.
    发明申请
    PLANT STRESS TOLERANCE GENES, AND USES THEREFOR 审中-公开

    公开(公告)号：WO2004044207A9

    公开(公告)日：2004-05-27

    申请号：PCT/CA2003/001754

    申请日：2003-11-14

    Applicant: UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. ,  ROBERTSON, Albert, James ,  GUSTA, Lawrence, Victor ,  WU, Guohai

    Inventor： ROBERTSON, Albert, James ,  GUSTA, Lawrence, Victor ,  WU, Guohai

    IPC: C12N15/82

    Abstract: Plant stresses such as pest infestations, disease, drought, flood, and excessive temperatures can lead to significant losses of crops each year. There is a continuing need to develop novel plant varieties that are less susceptible to damage or loss by such stresses. The present invention provides for the isolation, characterization and use of an entirely novel class of plant genes, generally designated ROB5 . Transgenic plants expressing ROB5 can show a dramatic improvement in their capacity to tolerate a variety of stress conditions. Moreover, ROB5 expression can further lead to marked increases in plant growth rates and plant vigor. The present invention encompasses all such ROB5 genes and peptides encoded thereby, plants expressing corresponding ROB5 constructs, and plant products thereof.

    A SHUNT AND METHOD TREATMENT OF GLAUCOMA
    9.
    发明申请
    A SHUNT AND METHOD TREATMENT OF GLAUCOMA 审中-公开
    GLAUCOMA的分流和方法处理

    公开(公告)号：WO2003099175A1

    公开(公告)日：2003-12-04

    申请号：PCT/CA2003/000774

    申请日：2003-05-29

    Applicant: UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. ,  GRAHN, Bruce, Harold ,  STOREY, Eric, Shad ,  STILLING, Denise, Sharon

    Inventor： GRAHN, Bruce, Harold ,  STOREY, Eric, Shad ,  STILLING, Denise, Sharon

    IPC: A61F9/007

    CPC classification number: A61M27/002 ,  A61F9/0017 ,  A61F9/00781 ,  A61M39/22 ,  A61M2210/0612

    Abstract: This invention provides a shunt for implantation between the anterior chamber of the eye and the epithelial-lined space through the frontal sinus bone of a patient for the treatment of glaucoma. The shunt includes a tube having a length sufficient to span the distance between the anterior chamber of the eye and the epithelial-lined space of the patient, the tube having an open anterior chamber end and a closed epithelial-lined space end, and a seal device associated with the tube between the anterior chamber and epithelial-lined space ends, for sealing a hole in the frontal sinus bone, and for anchoring the tube against movement from the frontal sinus bone. The shunt also includes a fluid pressure openable valve in the tube, located at or near the epithelial-lined space sinus end, allowing for controlled flow of aqueous humor through the tube when implanted. The invention also extends to a method of treating glaucoma in a patient by surgically implanting the shunt between the anterior chamber of the eye and the frontal sinus.

    Abstract translation: 本发明提供了一种用于在眼前房和通过患者的额窦骨的上皮内衬空间之间植入用于治疗青光眼的分流器。 该分流器包括具有足以跨越眼睛前房与患者上皮衬里空间之间距离的长度的管，该管具有开放的前房末端和封闭的上皮内衬空间端，以及密封 与前房和上皮衬里的空间端之间的管相关联的装置，用于密封额窦骨中的孔，并用于锚固管以防止从额窦骨移动。 分流器还包括管中的流体压力可打开的阀，位于上皮内衬的空间窦端处或附近，允许房水在植入时通过管的受控流动。 本发明还延伸到通过在眼前房和额窦之间手术植入分流器来治疗患者青光眼的方法。

    METHODS AND APPARATUS FOR MOLECULAR DATA STORAGE, RETRIEVAL AND ANALYSIS
    10.
    发明申请
    METHODS AND APPARATUS FOR MOLECULAR DATA STORAGE, RETRIEVAL AND ANALYSIS 审中-公开

    公开(公告)号：WO2003089666A3

    公开(公告)日：2003-10-30

    申请号：PCT/CA2003/000574

    申请日：2003-04-17

    Applicant: UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. ,  LEE, Jeremy, S. ,  WETTIG, Shawn, D. ,  KRAATZ, Heinz-Bernhard

    Inventor： LEE, Jeremy, S. ,  WETTIG, Shawn, D. ,  KRAATZ, Heinz-Bernhard

    IPC: G11C13/02

    Abstract: In various aspects, the invention provides molecular systems for storing and retrieving information. In some embodiments, polymers capable of selectively binding metal ions, such as nucleic acids, are used to record information in the form of a particular molecular conformation. Electrochemical assay methods employing nanopores may be used to read and write information using such polymeric media. In some embodiments, information may be recorded in a nucleic acid polymer by magnetically modulating the translocation of the nucleic acid through a channel in a medium, while simultaneously modulating the electrostatic potential across the channel. In this way, the incorporation of a divalent metal ion in the nucleic acid duplex may be modulated to store information. In an alternative aspect, the invention provides analogous processes for detecting a base pair mismatch in a nucleic acid polymer.

Patent Agency Ranking