公开(公告)号：US4596705A

公开(公告)日：1986-06-24

申请号：US539998

申请日：1983-10-07

Applicant: Gottfried Schepky ,  Rolf Brickl ,  Peter Gruber ,  Jochen Schmid ,  Ursula Springmeier

Inventor： Gottfried Schepky ,  Rolf Brickl ,  Peter Gruber ,  Jochen Schmid ,  Ursula Springmeier

IPC: C07D487/04 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61K9/50 ,  A61K9/52 ,  A61K31/505 ,  A61K47/12 ,  A61P7/02 ,  A61K9/22

CPC classification number: A61K9/2013 ,  A61K31/505 ,  A61K9/4841 ,  A61K9/5078

Abstract: This invention relates to vehicles for the administration of mopidamol. More specifically, this invention relates to a method of treating cardiovascular disorders, malignancy, or thrombosis in a host in need of such treatment which comprises administering to said host a cardiovascularly, antimetastic, or antithrombotic effective amount of a composition comprised of (i) mopidamol or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 1 acid equivalent to 1 mol of mopidamol.

Abstract translation: 本发明涉及给予莫匹达莫的载体。 更具体地说，本发明涉及在需要这种治疗的宿主中治疗心血管疾病，恶性肿瘤或血栓形成的方法，该方法包括向所述宿主施用心血管，抗重复或抗血栓形成的有效量的组合物，所述组合物包含（i）莫比达莫 或其酸加成盐和（ii）至少一种药理学上可接受的酸或酸物质，存在酸加成盐的酸的总量和酸或酸性物质的比例为至少约1当量酸1摩尔 莫比达莫

公开(公告)号：US4650664A

公开(公告)日：1987-03-17

申请号：US772166

申请日：1985-09-03

Applicant: Gottfried Schepky ,  Rolf Brickl ,  Peter Gruber ,  Jochen Schmid ,  Ursula Springmeier

Inventor： Gottfried Schepky ,  Rolf Brickl ,  Peter Gruber ,  Jochen Schmid ,  Ursula Springmeier

IPC: C07D487/04 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61K9/50 ,  A61K9/52 ,  A61K31/505 ,  A61K47/12 ,  A61P7/02 ,  A61K9/54

CPC classification number: A61K9/2013 ,  A61K31/505 ,  A61K9/4841 ,  A61K9/5078

Abstract: This invention relates to vehicles for the administration of mopidamol. More specifically, this invention relates to a method of treating cardiovascular disorders, malignancy, or thrombosis in a host in need of such treatment which comprises administering to said host a cardiovascularly, antimetastic, or antithrombotic effective amount of a composition comprised of (i) mopidamol or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 1 acid equivalent to 1 mol of mopidamol or its acid addition salt.

Abstract translation: 本发明涉及给予莫匹达莫的载体。 更具体地说，本发明涉及在需要这种治疗的宿主中治疗心血管疾病，恶性肿瘤或血栓形成的方法，该方法包括向所述宿主施用心血管，抗重复或抗血栓形成的有效量的组合物，所述组合物包含（i）莫比达莫 或其酸加成盐和（ii）至少一种药理学上可接受的酸或酸物质，存在酸加成盐的酸的总量和酸或酸性物质的比例为至少约1当量酸1摩尔 莫比达莫或其酸加成盐。