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公开(公告)号：WO2011119754A2
公开(公告)日：2011-09-29
申请号：PCT/US2011/029654
申请日：2011-03-23
Applicant: EDWARDS LIFESCIENCES CORPORATION , DOVE, Jeffrey, S. , TIAN, Bin , SCHNEIDER, Ralph , COHEN, Jeffrey, S. , JANKOVIC, Ivan , MIGLIAZZA, John, F. , WRIGHT, Gregory, A. , YOUNG, James, M. , CAMPBELL, Louis, A.
Inventor： DOVE, Jeffrey, S. , TIAN, Bin , SCHNEIDER, Ralph , COHEN, Jeffrey, S. , JANKOVIC, Ivan , MIGLIAZZA, John, F. , WRIGHT, Gregory, A. , YOUNG, James, M. , CAMPBELL, Louis, A.
CPC classification number: A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes. The finally thinned membrane may then be treated by capping of calcification nucleation sites and borohydride reduction. The leaflets may be formed to have more than one region of uniform thickness, such as a thicker peripheral sewing region.
Abstract translation: 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并平滑表面。 选择激光器的波长，功率和脉冲速率，这将使纤维表面平滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤表面从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用交联以稳定膜的逐步压缩来避免通过非弹性压缩损伤膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。 然后可以通过封闭钙化成核位点和硼氢化钠还原来处理最终变薄的膜。 传单可以形成为具有多于一个均匀厚度的区域，例如较厚的外围缝合区域。
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公开(公告)号：WO2011119754A3
公开(公告)日：2012-02-16
申请号：PCT/US2011029654
申请日：2011-03-23
Applicant: EDWARDS LIFESCIENCES CORP , DOVE JEFFREY S , TIAN BIN , SCHNEIDER RALPH , COHEN JEFFREY S , JANKOVIC IVAN , MIGLIAZZA JOHN F , WRIGHT GREGORY A , YOUNG JAMES M , CAMPBELL LOUIS A
Inventor： DOVE JEFFREY S , TIAN BIN , SCHNEIDER RALPH , COHEN JEFFREY S , JANKOVIC IVAN , MIGLIAZZA JOHN F , WRIGHT GREGORY A , YOUNG JAMES M , CAMPBELL LOUIS A
CPC classification number: A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes. The finally thinned membrane may then be treated by capping of calcification nucleation sites and borohydride reduction. The leaflets may be formed to have more than one region of uniform thickness, such as a thicker peripheral sewing region.
Abstract translation: 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并使表面平滑。 选择激光器的波长，功率和脉冲率，这将使纤维表面光滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤细胞从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用用于稳定膜的交联逐步压缩以避免通过非弹性压缩损坏膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。 然后可以通过封闭钙化成核位点和硼氢化钠还原来处理最终变薄的膜。 小叶可以形成为具有多于一个均匀厚度的区域，例如较厚的外围缝合区域。
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Patent Agency Ranking
公开(公告)号：US3639973A
公开(公告)日：1972-02-08
申请号：US3639973D
申请日：1970-03-06
Applicant: YOUNG JAMES M
Inventor： YOUNG JAMES M
CPC classification number: B28B23/22 , E04C3/22 , Y10T29/49874 , Y10T29/49888
Abstract: A method of making a multiple tendon, prestressed segmented concrete beam includes the steps of locating and stressing the tendons so as to produce equal compressive prestress laterally across the beam. The method eliminates the vertical end splitting which has occurred during the manufacture of multiple tendon beams in the past.
Abstract translation: 制造多筋，预应力分段混凝土梁的方法包括定位和应力钢筋的步骤，以便在横梁上横向产生相等的压缩预应力。 该方法消除了过去在多个腱束制造过程中发生的垂直分裂。
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公开(公告)号：US3561179A
公开(公告)日：1971-02-09
申请号：US3561179D
申请日：1968-04-29
Applicant: YOUNG JAMES M
Inventor： YOUNG JAMES M
Abstract: A PRESTRESSED, SEGMENTED CONCRETE BEAM, HAS THE TENSILE MEMBERS SO POSITIONED AND STRESSED AS TO EFFECTIVELY UTILIZE THE PRESTRESSING FORCES WHILE PREVENTING VERTICAL SHEARING OR SPLITTING AT THE ENDS OF THE BEAM. A METHOD OF MAKING SUCH A BEAM IS PROVIDED.
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公开(公告)号：US1334878A
公开(公告)日：1920-03-23
申请号：US30405219
申请日：1919-06-13
Applicant: YOUNG JAMES M
Inventor： YOUNG JAMES M
IPC: G02C3/02
CPC classification number: G02C3/02
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公开(公告)号：US987030A
公开(公告)日：1911-03-14
申请号：US1910570068
申请日：1910-07-02
Applicant: YOUNG JAMES M
Inventor： YOUNG JAMES M
CPC classification number: E03D5/092
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公开(公告)号：US854262A
公开(公告)日：1907-05-21
申请号：US1906333637
申请日：1906-09-07
Applicant: W J YOUNG , YOUNG JAMES M
Inventor： YOUNG JAMES M
CPC classification number: E05F13/04 , E05F11/54 , E05Y2201/676 , E05Y2800/00 , Y10S292/72 , Y10T292/1053 , Y10T292/19
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