公开(公告)号：WO1998006726A1

公开(公告)日：1998-02-19

申请号：PCT/JP1997002819

申请日：1997-08-12

Applicant: MITSUBISHI CHEMICAL CORPORATION ,  UBASAWA, Masaru ,  SEKIYA, Kouichi ,  TAKASHIMA, Hideaki ,  UEDA, Naoko ,  YUASA, Satoshi ,  KAMIYA, Naohiro

Inventor： MITSUBISHI CHEMICAL CORPORATION

IPC: C07F09/6561

CPC classification number: C07F9/6561 ,  C07F9/65616

Abstract: Phosphonate nucleotide compounds represented by general formula (I), their salts, hydrates and solvates thereof, and drugs containing the same, wherein R represents C1-6 alkyl, etc.; R represents hydrogen, halogenated C1-4 alkyl, etc.; R represents hydrogen, halogenated C1-4 alkyl, etc.; R represents hydrogen, halogenated C1-4 alkyl, etc.; and X represents carbon or nitrogen. These drugs are useful as antiviral agents for human immunodeficiency virus, herpes simplex virus, hepatitis B virus, etc., and as antitumor agents.

Abstract translation: 由通式（I）表示的膦酸酯核苷酸化合物，其盐，水合物和溶剂合物，以及含有该膦酸酯的化合物，其中R 1表示C 1-6烷基等; R 2表示氢，卤代C 1-4烷基等; R 3表示氢，卤代C 1-4烷基等; R 4代表氢，卤代C 1-4烷基等; X表示碳或氮。 这些药物可用作人类免疫缺陷病毒，单纯疱疹病毒，乙型肝炎病毒等的抗病毒剂，以及作为抗肿瘤剂。

公开(公告)号：WO2012026608A1

公开(公告)日：2012-03-01

申请号：PCT/JP2011/069370

申请日：2011-08-23

Applicant: CANON KABUSHIKI KAISHA ,  ITO, Shinzaburo ,  AOKI, Hiroyuki ,  MINAMI, Masato ,  FUKUI, Tatsuki ,  KATO, Kouichi ,  YAMAUCHI, Fumio ,  TOMIDA, Yoshinori ,  YUASA, Satoshi ,  YANO, Tetsuya ,  OGAWA, Satoshi ,  KANAZAKI, Kengo ,  SASAGURI, Daisuke ,  TAKAHASHI, Atsushi

Inventor： ITO, Shinzaburo ,  AOKI, Hiroyuki ,  MINAMI, Masato ,  FUKUI, Tatsuki ,  KATO, Kouichi ,  YAMAUCHI, Fumio ,  TOMIDA, Yoshinori ,  YUASA, Satoshi ,  YANO, Tetsuya ,  OGAWA, Satoshi ,  KANAZAKI, Kengo ,  SASAGURI, Daisuke ,  TAKAHASHI, Atsushi

IPC: A61K49/00 ,  A61K49/22 ,  B82Y5/00 ,  A61K9/51

CPC classification number: A61K49/0093 ,  A61K9/5153 ,  A61K49/0034 ,  A61K49/0052 ,  A61K49/225 ,  B82Y15/00 ,  B82Y30/00

Abstract: There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.

Abstract translation: 提供了一种负载ICG的聚合物纳米颗粒，其动态稳定，防止所含ICG的泄漏和所得的变色，并具有高的摩尔吸光系数。 该颗粒含有具有磺酸盐基团和疏水性聚合物的亲水性染料，并且该颗粒还含有具有带正电荷区域的脂质，烟酸衍生物和硫胺衍生物中的至少一种。

公开(公告)号：WO2004079439A3

公开(公告)日：2005-02-24

申请号：PCT/JP2004002931

申请日：2004-03-05

Applicant: CANON KK ,  YUASA SATOSHI

Inventor： YUASA SATOSHI

IPC: G02F1/13 ,  G02F1/1347 ,  G02F1/167 ,  G09G3/34 ,  G09G3/36

CPC classification number: G09G3/36 ,  G02F1/1347 ,  G02F1/13475 ,  G09G3/2003 ,  G09G3/344 ,  G09G3/3607 ,  G09G2300/023 ,  G09G2380/02

Abstract: An image display panel having, in a multilayer structure, a first (1) and second light (2) modulating layers each comprising a periodical planar arrangement of a plurality of light modulating elements (3, 4) for modulating a color or a brightness of an incident light in response to an input signal, wherein the arrangement period of the light modulating element in the first light modulating layer (3) is smaller than the arrangement period of the light modulating element in the second light modulating layer (4).

Abstract translation: 一种图像显示面板，具有多层结构的第一（1）和第二光（2），每个调制层包括多个光调制元件（3,4）的周期性平面布置，用于调制颜色或亮度 响应于输入信号的入射光，其中第一光调制层（3）中的光调制元件的布置周期小于第二光调制层（4）中的光调制元件的布置周期。

公开(公告)号：WO2003028737A1

公开(公告)日：2003-04-10

申请号：PCT/JP2002/008799

申请日：2002-08-30

Applicant: MITSUBISHI PHARMA CORPORATION ,  YUASA, Satoshi ,  KAMIYA, Naohiro

Inventor： YUASA, Satoshi ,  KAMIYA, Naohiro

IPC: A61K31/683

CPC classification number: A61K31/675 ,  A61K31/683 ,  A61K45/00 ,  C12Q1/48 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50

Abstract: The object of the present invention is to detect and identify a medicament which inhibits activation of viral polymerase via RNA binding, and also to provide an anti-viral agent using a medicament which inhibits activation of viral polymerase via RNA binding. The present invention provides an anti-viral agent comprising, as an active ingredient, a medicament which inhibits activation of viral polymerase via RNA binding.

Abstract translation: 本发明的目的是检测和鉴定通过RNA结合抑制病毒聚合酶活化的药物，并且还使用通过RNA结合抑制病毒聚合酶活化的药物提供抗病毒剂。 本发明提供了包含通过RNA结合抑制病毒聚合酶活化的药物作为活性成分的抗病毒剂。

公开(公告)号：WO2004079439A2

公开(公告)日：2004-09-16

申请号：PCT/JP2004/002931

申请日：2004-03-05

Applicant: CANON KABUSHIKI KAISHA ,  YUASA, Satoshi,

Inventor： YUASA, Satoshi,

IPC: G02F1/1347

CPC classification number: G09G3/36 ,  G02F1/1347 ,  G02F1/13475 ,  G09G3/2003 ,  G09G3/344 ,  G09G3/3607 ,  G09G2300/023 ,  G09G2380/02

Abstract: An image display panel having, in a multilayer structure, a first and second light modulating layers each comprising a periodical planar arrangement of a plurality of light modulating elements for modulating a color or a brightness of an incident light in response to an input signal, wherein the arrangement period of the light modulating element in the first light modulating layer is smaller than the arrangement period of the light modulating element in the second light modulating layer.

Abstract translation: 一种具有多层结构的第一和第二光调制层的图像显示板，每个第一和第二光调制层包括多个光调制元件的周期性平面布置，用于响应于输入信号调制入射光的颜色或亮度，其中 第一光调制层中的光调制元件的布置周期小于第二光调制层中的光调制元件的布置周期。

公开(公告)号：WO1997000262A1

公开(公告)日：1997-01-03

申请号：PCT/JP1996001631

申请日：1996-06-14

Applicant: MISTUBISHI CHEMICAL CORPORATION ,  UBASAWA, Masaru ,  TAKASHIMA, Hideaki ,  SEKIYA, Kouichi ,  INOUE, Naoko ,  YUASA, Satoshi ,  KAMIYA, Naohiro

Inventor： MISTUBISHI CHEMICAL CORPORATION

IPC: C07F09/6561

CPC classification number: C07F9/6561 ,  C07F9/65616

Abstract: A compound represented by general formula (I) and having an antiviral activity, wherein R represents hydrogen, C1-6 alkyl or C7-10 aralkyl; R represents C1-6 alkyl, C7-10 aralkyl or phenyl; R and R independently represent each hydrogen, C1-6 alkyl, acyloxymethyl, acylthioethyl or ethyl substituted by at least one halogen atom; R represents hydrogen, C1-4 alkyl, C1-4 hydroxyalkyl or C1-4 alkyl substituted by at least one halogen atom; and X represents carbon or nitrogen.

Abstract translation: 由通式（I）表示并具有抗病毒活性的化合物，其中R 1表示氢，C 1-6烷基或C 7-10芳烷基; R 2表示C 1-6烷基，C 7-10芳烷基或苯基; R 3和R 4独立地表示氢，C 1-6烷基，酰氧基甲基，酰硫基乙基或被至少一个卤素原子取代的乙基; R 5表示氢，C 1-4烷基，C 1-4羟基烷基或被至少一个卤素原子取代的C 1-4烷基; X表示碳或氮。