公开(公告)号：KR1020080029020A

公开(公告)日：2008-04-03

申请号：KR1020050110877

申请日：2005-11-18

Applicant: (주)셀트리온

Inventor： 이준원 ,  오혜연 ,  정순관 ,  장신재 ,  홍승서

IPC: A61K38/17 ,  C12N15/00 ,  C07K1/14

CPC classification number: A61K38/193 ,  A61K47/10 ,  A61K47/26 ,  C07K14/53

Abstract: An erythorpoietin composition is provided to maintain erythoropoietin stable, increase safety of the erythoropoietin and prevent the erythoropoietin from being absorbed into the container wall surface by comprising the erythoropoietin, Tween 20, propylene glcyol and mannitol. An erythorpoietin composition with storage stability comprises 100-100,000 IU of erythorpoietin, 0.0002-0.5% of Tween 20, 0.005-0.3% of propylene glycol, and 0.01-3% of mannitol.

Abstract translation: 提供促红细胞生成素组合物以维持促红细胞生成素稳定，增加促红细胞生成素的安全性，并且通过包含促红细胞生成素，吐温20，丙烯甘油醇和甘露醇，防止促红细胞生成素被吸收到容器壁表面。 具有保存稳定性的促红细胞生成素组合物包含100-100,000IU的促红细胞生成素，0.0002-0.5％的吐温20,0.005-0.3％的丙二醇和0.01-3％的甘露醇。