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公开(公告)号：KR1020140102950A
公开(公告)日：2014-08-25
申请号：KR1020130016495
申请日：2013-02-15
Applicant: 강원대학교산학협력단
CPC classification number: A61K38/47 , A61K8/99 , A61K36/07 , A61Q19/005
Abstract: The present invention relates to a pharmaceutical composition comprising chitinase as an active ingredient for preventing or treating atopic dermatitis and, more specifically, to a pharmaceutical composition for preventing or treating atopic dermatitis and a cosmetic composition for preventing or alleviating atopic dermatitis, comprising chitinase 2 (Chi 2) as an active ingredient. Chitinase 2 (Chi 2) according to the present invention effectively suppresses germination and growth of a spore of an atopic dermatitis-causing bacterium, excellently inhibits vasodilatation induced from atopic dermatitis, and may be used for preparing a medicine and a functional cosmetic for preventing, alleviating, or treating atopic dermatitis.
Abstract translation: 本发明涉及包含几丁质酶作为预防或治疗特应性皮炎的活性成分的药物组合物，更具体地，涉及用于预防或治疗特应性皮炎的药物组合物和用于预防或减轻特应性皮炎的化妆品组合物，其包含几丁质酶2（ Chi 2）作为活性成分。 根据本发明的几丁质酶2（Chi2）有效抑制特应性致敏细菌孢子的发芽和生长，优异地抑制由特应性皮炎引起的血管扩张，可用于制备药物和功能性化妆品， 缓解或治疗特应性皮炎。
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公开(公告)号：KR101791286B1
公开(公告)日：2017-10-30
申请号：KR1020130016495
申请日：2013-02-15
Applicant: 강원대학교산학협력단
Abstract: 본발명은키틴질분해효소를유효성분으로포함하는아토피의예방또는치료용약학적조성물에관한것으로서, 구체적으로키틴질분해효소 2(Chitinase 2, Chi2)를유효성분으로포함하는아토피의예방또는치료용약학적조성물및 아토피예방및 개선용화장료조성물에관한것이다. 본발명에따른키틴질분해효소 2(Chitinase 2, Chi2)는아토피원인균의포자발아와생장을효과적으로억제하는활성이있고, 아토피로유도되는혈관확장억제또한우수하여, 아토피증상을예방, 개선및 치료할수 있는의약품및 기능성화장품의제조에유용하게사용할수 있다.
Abstract translation: 本发明涉及含有几丁质分解酶作为有效成分，具体而言，几丁质分解酶2（几丁质酶2，χ2）特应性皮炎，包括作为活性成分的物质的药物组合物预防或治疗特应性的预防或治疗药物的医药组合物 以及用于预防和改善特应症的化妆品组合物。 几丁质分解酶2（几丁质酶2，χ2）根据本发明的孢子发芽并有效地抑制特应性微生物的生长的活性，抑制血管舒张由特应性诱导和也优异，可以预防，改善和治疗特应性症状 并且可以有效地用于药物和功能性化妆品的制造。
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