참가죽그물바탕말(Dictyota coriaceae)을 이용한 관절염 치료제
    1.
    发明授权

    公开(公告)号:KR101084926B1

    公开(公告)日:2011-11-17

    申请号:KR1020110026265

    申请日:2011-03-24

    Inventor: 김현표 정재훈

    Abstract: PURPOSE: A composition containing Dictyota coriaceae extract or fraction is provided to suppress the expression of MMP-1 and to treat and preventing degenerative arthritis. CONSTITUTION: A pharmaceutical composition for preventing and treating degenerative arthritis or rheumatoid arthritis contains Dictyota coriaceae extract as an active ingredient. A method for preparing the extract comprises: a step of adding 5-50 time(v/w) of water or mixture solvent of water and ethanol to Dictyota coriaceae by enfleurage; a step of filtering and drying the extract; a step of suspending the extract in 1-50 times voluyme(v/w) of water; and a step of fractioning with hexane, chloroform, methylene chloride, or ethyl acetate. A neutraceutical food for preventing and treating degenerative arthritis or rheumatoid arthritis contains the extract as an active ingredient.

    Abstract translation: 目的:提供含有Dictyota coriaceae提取物或级分的组合物以抑制MMP-1的表达并治疗和预防退行性关节炎。 构成:用于预防和治疗退行性关节炎或类风湿性关节炎的药物组合物含有茜草科提取物作为活性成分。 制备提取物的方法包括:通过灌肠向茜草科加入5-50次(v / w)水或水和乙醇的混合溶剂的步骤; 过滤和干燥提取物的步骤; 将提取物悬浮在1-50倍体积(v / w)的水中的步骤; 和用己烷,氯仿,二氯甲烷或乙酸乙酯分馏的步骤。 用于预防和治疗退行性关节炎或类风湿性关节炎的营养食品含有提取物作为活性成分。

    산조인 및 복령의 조합 추출물을 포함하는 불안증 또는 불면증의 치료 및 예방용 조성물
    2.
    发明公开
    산조인 및 복령의 조합 추출물을 포함하는 불안증 또는 불면증의 치료 및 예방용 조성물 无效
    组合物包括枸杞子和多糖的组合提取物用于治疗和预防安非他酮或胰岛素

    公开(公告)号:KR1020160077727A

    公开(公告)日:2016-07-04

    申请号:KR1020140188000

    申请日:2014-12-24

    Inventor: 김현표 정재훈

    CPC classification number: A61K36/725 A23L33/105 A61K36/076

    Abstract: 본발명은산조인및 복령조합추출물을포함하는불안증또는불면증의치료및 예방용조성물에관한것으로, 상세하게는본 발명의조합추출물은 ICR 웅성생쥐를이용한펜토바비탈나트륨 (Pentobarbita sodium) 유도수면에대한효능시험(실험예 1); ICR 웅성생쥐을이용한일반운동활성시험(Open field test) (실험예 2); 회전판(rotating rod)에서운동활성에대한효과시험을통하여산조인또는복령추출물단독에서는나타나지않는유의적인수면연장효과가산조인및 복령추출물과의조합으로당업자가예기치못한불면증치료효과가상승적으로나타남을확인하여불면증의치료및 예방의유용한약학조성물또는건강기능식품으로서사용할수 있다.

    Abstract translation: 本发明涉及包含Zizyphi Semen和Poria cocos的组合提取物的组合物,用于治疗和预防焦虑或失眠。 更具体地,本发明的组合提取物显示出通过Zizyphi Semen与茯苓科植物的组合延长睡眠的显着效果,其通过以下测试确定不能被单独的提取物或Zizyphi Semen或Poria cocos显示:a 使用ICR雄性大鼠测定戊巴比妥钠诱导睡眠的影响的测试(测试实施例1) 使用ICR雄性大鼠的野外试验(试验例2) 以及用于确定在旋转杆中对运动活动的影响的测试。 因此,可以获得本领域技术人员不能期待的治疗失眠的协同效应。 因此,根据本发明的组合物可以用作用于治疗和预防失眠的药物组合物或保健食品。

    참가죽그물바탕말 추출물을 유효성분으로 함유하는 퇴행성 뇌질환 치료 및 예방용 조성물
    3.
    发明授权
    참가죽그물바탕말 추출물을 유효성분으로 함유하는 퇴행성 뇌질환 치료 및 예방용 조성물 有权
    包括提取苦丁酸处理和预防神经变性疾病的组合物

    公开(公告)号:KR101106376B1

    公开(公告)日:2012-01-18

    申请号:KR1020110027357

    申请日:2011-03-28

    Inventor: 김현표 정재훈

    Abstract: PURPOSE: A pharmaceutical composition or health food containing Dictyota coriacea extract is provided to improve learning and space perception ability. CONSTITUTION: A pharmaceutical composition for preventing and treating Alzheimer dementia contains water and ethanol mixture extract of Dictyota coriacea as an active ingredient. A health food for preventing and treating Alzheimer dementia contains the extract as an active ingredient. The extract is isolated using water, low alcohol of C1-C4, or mixture solvent thereof. A health food for preventing and treating amnesia and neurodegenerative diseases contains the extract as an active ingredient.

    Abstract translation: 目的:提供含有Dictyota coriacea提取物的药物组合物或保健食品,以提高学习和空间感知能力。 构成:用于预防和治疗阿尔茨海默氏痴呆的药物组合物含有Dictyota coriacea的水和乙醇混合物提取物作为活性成分。 用于预防和治疗阿尔茨海默氏痴呆症的保健食品含有提取物作为活性成分。 使用水,C1-C4的低级醇或其混合溶剂分离提取物。 用于预防和治疗遗忘症和神经退行性疾病的保健食品含有提取物作为活性成分。

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