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公开(公告)号：KR102223958B1
公开(公告)日：2021-03-08
申请号：KR1020180118817A
申请日：2018-10-05
Applicant: 건국대학교 산학협력단
IPC: C08L1/28 , A61F13/02 , A61K9/06 , A61K31/65 , A61K47/40 , A61L27/52 , A61L27/56 , C08J3/075 , C08J3/24 , C08K5/1515 , C12N5/00
CPC classification number: C08L1/286 , A61F13/0213 , A61K31/65 , A61K47/40 , A61K9/06 , A61L27/52 , A61L27/56 , C08J3/075 , C08J3/24 , C08K5/1515 , C08L5/16 , C12N5/0068 , A61F2013/00748 , A61L2430/34 , C08J2205/022 , C12N2533/30
Abstract: 본 발명은 기계적 강도를 향상시킨 소수성 약물 전달용 카르복시메틸셀룰로오스 기반 초흡수성 하이드로젤에 관한 것이다. 본 발명에 따른 하이드로젤은 팽윤성을 감소시키지 않으면서 CMC 하이드로젤의 기계적 강도를 크게 향상시킬 수 있고, 우수한 팽윤성에 기인하여 소수성 약물 방출 특성이 우수하고, 효과적인 살균 활성을 가질 수 있다.
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公开(公告)号：KR1020090017244A
公开(公告)日：2009-02-18
申请号：KR1020070081841
申请日：2007-08-14
Applicant: 건국대학교 산학협력단
CPC classification number: B01J31/06 , C07C253/32 , C07C255/25 , C07C269/06 , C07C2601/14
Abstract: A material that catalyzes an environmentally friendly strecker reaction is provided, and a method for producing alpha-aminonitrile using the material that catalyzes the environmentally friendly strecker reaction is provided. A carbohydrate catalyst catalyzing a strecker reaction is a compound represented by the following formula A or B. R1 and R2 of the compound of the formula B are a hydroxyl group(-OH) or a succinyl group. The R1 of the compound of the formula B is the hydroxyl group(-OH), and the R2 of the compound of the formula B is the succinyl group. A matrix of the strecker reaction in which the catalyst engages is malonaldehyde bis(phenylimine), N-benzylidene benzene sulfoneamine, or N-benzylidene-N-(diphenylmethyl)amine. The compound of the formula A is derived from X. oryzae pv. oryzae KACC 10331. The compound of the formula B is derived from Rhizobium meliloti 1021(ATCC 51124).
Abstract translation: 提供催化环境友好的沥青路面反应的材料，并提供使用催化环境友好的沥青路面反应的材料生产α-氨基腈的方法。 催化催化剂反应的碳水化合物催化剂是由下式A或B表示的化合物。式B化合物的R 1和R 2是羟基（-OH）或琥珀酰基。 式B化合物的R1是羟基（-OH），式B化合物的R2是琥珀酰基。 催化剂接合的催化剂反应的基质是丙二醛双（苯亚胺），N-亚苄基苯磺胺或N-亚苄基-N-（二苯基甲基）胺。 式A的化合物衍生自米曲霉 米曲霉KACC 10331.式B的化合物衍生自根瘤菌根瘤菌（Rhizobium meliloti）1021（ATCC 51124）。
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公开(公告)号：KR1020150084535A
公开(公告)日：2015-07-22
申请号：KR1020140004652
申请日：2014-01-14
Applicant: 건국대학교 산학협력단
IPC: A61K47/40 , A61K31/14 , A61K31/352 , A61K31/35
CPC classification number: A61K47/40 , A61K31/352 , A61K47/61
Abstract: 본발명은피세틴의수용성및 생체이용률을개선하는조성물및 그방법에관한것으로더욱상세하게는사이클로소포라오스(cyclosophoraose) 다이머를유효성분으로포함하는난용성플라보노이드의수용성및 생체이용률개선용조성물및 방법에관한것이다.
Abstract translation: 本发明涉及一种用于提高非瑟酮的溶解性和生物利用度的组合物和方法，更具体地说，涉及一种用于提高不溶性类黄酮含量的环孢菌二聚体作为活性成分的溶解性和生物利用度的组合物和方法。
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Patent Agency Ranking
公开(公告)号：KR1020130113198A
公开(公告)日：2013-10-15
申请号：KR1020120035590
申请日：2012-04-05
Applicant: 건국대학교 산학협력단
CPC classification number: A61K47/36 , A61K31/451 , Y10S514/97
Abstract: PURPOSE: Acyclic succinoglycan is provided to be used as a novel solubilizing agent and a therapeutic agent because the acyclic succinoglycan is a safe biomaterial. CONSTITUTION: A solubilizing composition contains compounds of chemical formula 1 as an active ingredient. The compound is derived from Sinorhizobium melioti. The composition contains the compound of chemical formula 1 and a therapeutic drug. The therapeutic drug is haloperidol.
Abstract translation: 目的：提供非环状琥珀酰聚糖作为新型增溶剂和治疗剂，因为无环琥珀酰聚糖是安全的生物材料。 构成：增溶组合物含有化学式1的化合物作为活性成分。 该化合物衍生自中华根瘤菌（Sinorhizobium melioti）。 该组合物含有化学式1的化合物和治疗药物。 治疗药物是氟哌啶醇。
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公开(公告)号：KR102223958B1
公开(公告)日：2021-03-08
申请号：KR1020180118817
申请日：2018-10-05
Applicant: 건국대학교 산학협력단
IPC: C08L1/28 , A61K9/06 , A61K47/40 , A61K31/65 , C08J3/075 , C08J3/24 , C08K5/1515 , A61F13/02 , A61L27/52 , A61L27/56 , C12N5/00 , A61F13/00
Abstract: 본발명은기계적강도를향상시킨소수성약물전달용카르복시메틸셀룰로오스기반초흡수성하이드로젤에관한것이다. 본발명에따른하이드로젤은팽윤성을감소시키지않으면서 CMC 하이드로젤의기계적강도를크게향상시킬수 있고, 우수한팽윤성에기인하여소수성약물방출특성이우수하고, 효과적인살균활성을가질수 있다.
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公开(公告)号：KR1020180015939A
公开(公告)日：2018-02-14
申请号：KR1020160099574
申请日：2016-08-04
Applicant: 건국대학교 산학협력단
IPC: A61K9/48 , A61K9/50 , A61K31/352
CPC classification number: A61K9/4866 , A61K9/5036 , A61K9/5042 , A61K31/352
Abstract: 본발명은본 발명은소수성분자포집용조성물및 상기조성물에항박테리아활성을가지는약물을탑재한박테리아감염의예방또는치료용조성물에관한것이다. 본발명은소수성약물이효율적으로포집될뿐 아니라팽윤력, 긴보수(water retention) 시간및 우수한약물방출패턴을보이면서도세포독성을나타내지않아우수한전달시스템으로유용하게이용될수 있다.
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公开(公告)号：KR101639160B1
公开(公告)日：2016-07-12
申请号：KR1020150081977
申请日：2015-06-10
Applicant: 건국대학교 산학협력단
Inventor： 정선호 , 조은애 , 무하메드나지르타히르 , 김환희 , 유재혁
IPC: B01J20/26 , B01J20/32 , C02F103/30 , C02F103/28
CPC classification number: Y02W10/37
Abstract: 본발명은신규한 N-벤질트리아졸덱스트란유도체화합물, 이의제조방법및 이를이용한메틸바이올렛흡착용조성물에관한것이다.
Abstract translation: 本发明涉及由化学式1表示的新型N-苄基三唑葡聚糖衍生物化合物及其制备方法和使用其的吸收甲基紫色素的组合物。
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公开(公告)号：KR1020150087002A
公开(公告)日：2015-07-29
申请号：KR1020140007348
申请日：2014-01-21
Applicant: 건국대학교 산학협력단
CPC classification number: C08B37/0006 , A61K31/352 , A61K47/36
Abstract: 본발명은알파-나프토플라본의수용성개선용조성물및 그방법에관한것으로더욱상세하게는하이드록시프로필사이클로소포라오스를유효성분으로포함하는난용성플라보노이드의수용성개선용조성물및 방법에관한것이다.
Abstract translation: 本发明涉及一种改善α-萘并噻吩的水溶性的组合物及其方法，更具体地说涉及一种组合物和改善水溶性差的类黄酮的水溶性的方法，所述组合物和水溶性包括环糊精羟丙酯作为活性成分。 本发明包括由化学式1表示的环丙基羟丙基纤维素。因此，与C-CD相比，HP Cys能够有效地增加α-NF的溶解度。
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