Abstract:
PURPOSE: A pharmaceutical composition containing piperine or plant extract for preventing or treating arthritis is provided to suppress generation of IL-6, PGE2, MMP-1, and MMP-13. CONSTITUTION: A pharmaceutical composition for suppressing or treating arthritis contains piperine or plant extract as an active ingredient. The arthritis is rhematic arthritis. The composition suppresses IL-6, prostaglandin E2, COX-2(cyclooxygenase 2), MMP-1(matrix metalloprotease 1) or MMP-13 generation. A health food for suppressing or treating arthritis contains piperine or plant extract as an active ingredient.