진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물
    1.
    发明公开
    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물 有权
    用于预防和治疗含有GINSENOSIDE Rbl和Rg3的神经性疼痛的组合物,化合物K或来自PANAX GINSENG的SAPONIN提取物作为有效成分

    公开(公告)号:KR1020130025926A

    公开(公告)日:2013-03-12

    申请号:KR1020130010544

    申请日:2013-01-30

    Abstract: PURPOSE: A composition for preventing and treating neuropathic pain containing a ginseng originated saponin extract or saponin separated from the same is provided to apply the composition to produce health food. CONSTITUTION: Health food for preventing and treating neuropathic pain contains ginsenoside Rg3 denoted by chemical formula 3 as an active ingredient. In the chemical formula, R1 is Glc2-Glc and R2 is H. A composition for preventing and treating spinal cord injury contains 0.1-50wt% of ginseng originated saponin extract for the total amount of the composition. The composition for preventing and treating spinal cord injury can be produced into a form selected from: oral dosage forms including powder, granules, tablets, capsules, soft capsules, suspension, emulsion, syrup, or aerosol; and other dosage forms including external preparations, suppositories, or sterilized injection liquid.

    Abstract translation: 目的:提供用于预防和治疗包含与其分离的人参起始皂甙提取物或皂甙的神经性疼痛的组合物以施用该组合物以产生保健食品。 构成:用于预防和治疗神经性疼痛的保健食品含有由化学式3表示的人参皂苷Rg3作为活性成分。 在化学式中,R1是Glc2-Glc,R2是H.用于预防和治疗脊髓损伤的组合物含有0.1-50wt%的人参起始皂苷提取物,用于组合物的总量。 用于预防和治疗脊髓损伤的组合物可以制成选自以下形式:口服剂型,包括粉末,颗粒,片剂,胶囊,软胶囊,悬浮液,乳剂,糖浆或气雾剂; 和其它剂型,包括外用制剂,栓剂或灭菌注射液。

    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물
    2.
    发明公开
    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물 有权
    用于预防和治疗含有GINSENOSIDE RB1和RG3的神经性疼痛的组合物,化合物K或来自PANAX GINSENG的SAPONIN提取物作为有效成分

    公开(公告)号:KR1020120082637A

    公开(公告)日:2012-07-24

    申请号:KR1020110004037

    申请日:2011-01-14

    CPC classification number: A61K36/258 A23V2200/322

    Abstract: PURPOSE: A composition containing ginsenoside Rb1 and Rg3, compound K, or ginseng-derived saponin extract is provided to suppress pain caused by peripheral nerve injury, central nervous injury, and inflammation. CONSTITUTION: A composition for preventing and treating neuropathic pain contains Panax ginseng-derived saponin extract or saponin isolated from the extract as an active ingredient. The extract is prepared using water, C1-C12 alcohol, or a mixture thereof. A composition contains a compound of chemical formula 1 isolated from the saponin extract as an active ingredient. The compound includes ginsenoside Rb1 of chemical formula 2, ginsenoide Rg3 of chemical formula 3, and compound K of chemical formula 4.

    Abstract translation: 目的:提供含有人参皂苷Rb1和Rg3,化合物K或人参皂甙提取物的组合物,以抑制由周围神经损伤,中枢神经损伤和炎症引起的疼痛。 构成:用于预防和治疗神经性疼痛的组合物含有作为活性成分从提取物中分离的人参来源的皂甙提取物或皂角苷。 提取物是使用水,C1-C12醇或其混合物制备的。 组合物含有从皂甙提取物中分离出的化学式1化合物作为活性成分。 该化合物包括化学式2的人参皂苷Rb1,化学式3的人参皂苷Rg3和化学式4的化合物K.

    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물
    5.
    发明公开
    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물 有权
    用于预防和治疗含有GINSENOSIDE Rbl和Rg3的神经性疼痛的组合物,化合物K或来自PANAX GINSENG的SAPONIN提取物作为有效成分

    公开(公告)号:KR1020130024942A

    公开(公告)日:2013-03-08

    申请号:KR1020130010545

    申请日:2013-01-30

    CPC classification number: A61K36/258 A23L33/105 A23V2200/322 A61K2039/55577

    Abstract: PURPOSE: A composition containing ginsenoside Rb1 and Rg3, compound K, or a ginseng-derived saponin extract is provided to suppress the pain caused by inflammation. CONSTITUTION: A pharmaceutical composition for preventing and treating neuropathic pain contains ginsenoside Rb1 and Rg3, compound K, or a ginseng-derived saponin extract as active ingredients. The pharmaceutical composition for preventing and treating neuropathic pain contains ginsenoside compound K as an active ingredient. [Reference numerals] (AA,BB) Paw withdrawal threshold(g); (CC,DD,GG,HH) Time after injection(hour); (EE,FF) Paw withdrawal latency(s)

    Abstract translation: 目的:提供含有人参皂苷Rb1和Rg3,化合物K或人参来源的皂甙提取物的组合物,以抑制由炎症引起的疼痛。 构成:用于预防和治疗神经性疼痛的药物组合物包含人参皂苷Rb1和Rg3,化合物K或人参衍生的皂苷提取物作为活性成分。 用于预防和治疗神经性疼痛的药物组合物含有人参皂苷化合物K作为有效成分。 (参考编号)(AA,BB)爪退出阈值(g); (CC,DD,GG,HH)注射后时间(小时); (EE,FF)爪退出延迟(s)

    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물
    6.
    发明授权
    진세노사이드 Rb1 및 Rg3,Compound K,또는 인삼유래 사포닌 추출물을 유효성분으로 함유하는 신경병증성 통증 예방 및 치료용 조성물 有权
    用于预防和治疗神经性疼痛的组合物,其包含人参皂甙Rb1和Rg3,化合物K或来源于人参的皂苷提取物作为活性成分

    公开(公告)号:KR101263451B1

    公开(公告)日:2013-05-10

    申请号:KR1020110004037

    申请日:2011-01-14

    Abstract: 본발명은진세노사이드 Rb1 및 Rg3, Compound K, 또는인삼유래사포닌추출물을유효성분으로함유하는신경병증성통증예방및 치료용조성물에관한것으로서, 구체적으로진세노사이드 Rb1 및 Rg3, Compound K, 또는인삼유래사포닌추출물각각의중추신경손상, 말초신경손상및 염증으로유발된통증을억제하는효과를확인하였으며, 이러한통증의억제효과는에스트로겐수용체를매개하여일어나며또한척수내미세교신경세포의통증관련인자발현을억제함으로써작용한다.

    Abstract translation: 本发明恩金人参皂苷Rb1和皂苷Rg3,化合物K,或人参皂苷衍生的提取物作为含有,作为活性成分,神经性疼痛的预防和对,具体的处理组合物,人参皂苷Rb1和皂苷Rg3,化合物K,或人参 雌激素受体介质抑制皂苷提取物对中枢神经系统损伤,周围神经损伤和炎症的抑制作用, Lt。

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