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公开(公告)号：KR1020140089996A
公开(公告)日：2014-07-16
申请号：KR1020130002173
申请日：2013-01-08
Applicant: 고려대학교 산학협력단
Abstract: The present invention relates to a manufacturing method for a PDMS microchannel for an immunosensor, which uses a mixed mold of glass bead-SU8 instead of the existing SU8 mold. The manufacturing method for a microchannel is implemented by the same process as the existing SU8 mold manufacturing process except the use of a glass bead-SU8 mixture instead of SU8 and plasma processing on a wafer, and does not add any complex process for transforming the inner surface of a microchannel. In addition, the manufacturing method for an immunosensor can have a large surface area in order to efficiently fixate an antibody, and can obtain a PDMS microchannel having a surface with high hydrophobicity. The microchannel can be utilized as an immunosensor by effectively fixating protein particles therein.
Abstract translation: 本发明涉及一种用于免疫传感器的PDMS微通道的制造方法，其使用玻璃珠SU8的混合模具代替现有的SU8模具。 微通道的制造方法通过与现有的SU8模具制造方法相同的方法实现，除了使用玻璃珠SU8混合物代替SU8和在晶片上进行等离子体处理，并且不添加用于转换内部的任何复杂的工艺 微通道表面。 此外，免疫传感器的制造方法可以具有大的表面积，以有效地固定抗体，并且可以获得具有高疏水性表面的PDMS微通道。 微通道可以通过有效地固定其中的蛋白质颗粒而用作免疫传感器。
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公开(公告)号：KR101533425B1
公开(公告)日：2015-07-02
申请号：KR1020130002173
申请日：2013-01-08
Applicant: 고려대학교 산학협력단
Abstract: 본발명은면역센서용 PDMS 미세채널을제조하는방법에있어서, 몰드의제조시기존의 SU8 몰드대신유리비드-SU8의혼합몰드를사용한것을특징으로한다. 본발명의미세채널제조방법은, SU8대신유리비드-SU8 혼합물을사용하고웨이퍼에 O플라즈마처리를하는것 외에는기존의 SU8 몰드제작공정과동일한공정으로진행되고, 미세채널내부표면의변형을위하여복잡한공정이추가되지않는다는점에서유리하다. 또한, 본발명의미세채널제조방법에의하면, 항체를효율적으로고정시키도록넓은표면적을가질뿐 아니라, 표면의소수성이높은 PDMS 미세채널을얻을수 있으며, 이러한미세채널은그 내부에단백질입자를효과적으로고정시킬수 있으므로, 면역센서로서활용가능성이높다.
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