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公开(公告)号：KR101894100B1
公开(公告)日：2018-08-31
申请号：KR1020120021319
申请日：2012-02-29
Applicant: 고려대학교 산학협력단
Abstract: 본발명은바이오센서에관한것이다. 본발명의일 실시예에따른바이오센서는, 검출부를포함하는하부플레이트, 하부플레이트와결합하고, 서로나란히위치하는제1 상부플레이트와제2 상부플레이트를포함하는상부플레이트및 하부플레이트와상부플레이트사이에위치하는필터를포함하고, 제1 상부플레이트는필터와대응하는위치에형성된검체투입부와, 제2 상부플레이트와인접한면에서제2 상부플레이트를향해돌출된제1 돌출부를포함하고, 제2 상부플레이트는제1 상부플레이트와인접한면에서제1 상부플레이트를향해돌출된제2 돌출부를포함하며, 제1 상부플레이트와제2 상부플레이트는제1 돌출부와제2 돌출부의접합에의해결합한다. 이에의해, 액상인검체의누수를방지하고, 검체로부터분석물질을신속하게분리할수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020140054743A
公开(公告)日：2014-05-09
申请号：KR1020120120609
申请日：2012-10-29
Applicant: 고려대학교 산학협력단
Abstract: The present invention discloses a microfluidic circuit element. The microfluidic circuit element of the present invention includes: microfluidic channels including grooves formed on a substrate; and fluid sample inlets and outlets which are formed on the upper surface and are connected to the both ends of the microfluidic channels. Fluid samples are injected to the microfluidic channels through the inlets to flow inside the channel, and are discharged through the outlets after the reaction is completed. Nano-interstices shorter than the center units of the microfluidic channels are formed on at least one corner unit of the both inner side walls of the microfluidic channels by using the flow direction of the fluid samples as a reference. And a flow delay unit is formed on a nano-interstice to slow the flow of the fluid samples.
Abstract translation: 本发明公开了一种微流体电路元件。 本发明的微流体电路元件包括：微流体通道，其包括形成在基板上的凹槽; 以及形成在上表面上并连接到微流体通道的两端的流体样品入口和出口。 流体样品通过入口注入微流体通道，在通道内流动，并在反应完成后通过出口排出。 通过使用流体样品的流动方向作为参考，在微流体通道的两个内侧壁的至少一个角部单元上形成比微流体通道的中心单元短的纳米空隙。 并且在纳米间隙上形成流动延迟单元以减缓流体样品的流动。
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公开(公告)号：KR101816933B1
公开(公告)日：2018-01-09
申请号：KR1020120028960
申请日：2012-03-21
Applicant: 고려대학교 산학협력단
IPC: G01N33/53 , G01N33/538
Abstract: 본발명은바이오센서및 그의작동방법을개시한다. 본발명은, 검체가유동하는제 1 채널이형성되며, 상기제 1 채널로상기검체를주입하는검체주입홀이형성되는바디부와, 상기바디부에형성되어상기제 1 채널및 외부와연결되어상기제 1 채널내부의공기를외부로배출시키는벤트홀부와, 상기검체주입홀및 외부에노출되는상기벤트홀부의입구부중 적어도하나에연결되어미리설정된시간에따라상기검체주입홀및 상기벤트홀부의입구부중 적어도하나를개폐시키는밸브를포함한다.
Abstract translation: 本发明公开了一种生物传感器及其操作方法。 本发明中，第一信道被形成为样品流，以及主体部，其在所述主体部分形成有用于将样品注入该第一沟道形成样品注入孔被连接到所述第一信道和一个外 通气孔部分，用于将第一通道内的空气排放到外部;以及通气孔部分，用于将样本注射器孔的入口和通气孔部分连接到通气孔部分的入口端口， 至少有一个用于打开和关闭阀门的阀门。
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公开(公告)号：KR101475440B1
公开(公告)日：2014-12-22
申请号：KR1020120120609
申请日：2012-10-29
Applicant: 고려대학교 산학협력단
Abstract: 본발명은미세유체회로소자를개시한다. 본발명은, 기재내부에형성된홈을포함하는미세유체채널, 및상기기재의상면에형성되고미세유체채널의양 말단과각각연결된유체시료투입구및 배출구를포함하여, 상기유체시료가상기투입구를통해상기미세유체채널에주입되어채널을흐르면서반응을완료된뒤 상기배출구를통해배출되도록형성되는미세유체회로소자로서, 상기유체시료의흐름방향을기준으로상기미세유체채널의양 측면내벽의모서리부중 적어도하나에상기미세유체채널의중앙부보다낮은높이의나노틈새가형성되고, 상기나노틈새에는상기유체시료의속도를지연시키는유속지연부가형성된다.
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公开(公告)号：KR1020130107119A
公开(公告)日：2013-10-01
申请号：KR1020120028960
申请日：2012-03-21
Applicant: 고려대학교 산학협력단
IPC: G01N33/53 , G01N33/538
Abstract: PURPOSE: A biosensor is provided to enable simple preparation without a separate driving force for transferring a sample, for example a pump. CONSTITUTION: A biosensor (100) comprises: a body part (110) which has a first channel in which a sample flows and a sample injection hole (121) for injecting the sample to the first channel; a bent hole part which is formed at the body part and discharges air in the first channel to the outside by being connected to the outside; and a valve (170) which is connected to the sample injection hole and/or the inlet of the bent hole part and opens and closes the sample injection hole and/or the inlet according to a predetermined time. A method for operating the biosensor comprises the steps of: placing the sample at the inlet of the first channel and moving the sample along the first channel; measuring the flow rate of the sample; and controlling the sample injection hole and/or the bent hole part based on the measured flow rate of the sample.
Abstract translation: 目的：提供一种生物传感器，以便在没有单独驱动力的情况下进行简单的准备来传送样品，例如泵。 构成：生物传感器（100）包括：身体部分（110），其具有样品流过的第一通道和用于将样品注射到第一通道的样品注入孔（121）; 弯曲孔部，其形成在主体部，并且通过与外部连接而将第一通道中的空气排出到外部; 以及连接到样品注入孔和/或弯曲孔部的入口的阀（170），并且在预定时间内打开和关闭样品注入孔和/或入口。 用于操作生物传感器的方法包括以下步骤：将样品放置在第一通道的入口处并沿着第一通道移动样品; 测量样品的流速; 并且基于所测量的样品流量控制样品注入孔和/或弯曲孔部分。
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公开(公告)号：KR1020130099648A
公开(公告)日：2013-09-06
申请号：KR1020120021319
申请日：2012-02-29
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: A biosensor is provided to rapidly separate an analysis object from a specimen, and to prevent the leakage of the specimen. CONSTITUTION: A biosensor (10) comprises: a lower plate (200) including a detection unit; an upper plate (100) including a first upper plate (110) and a second upper plate (120) facing each other, and being combined to the lower plate; and a filter located in between the lower and upper plates. The first upper plate includes a specimen insertion unit (114) formed on the location corresponding to the filter, and a first protrusion (112) protruded toward the second upper plate. The second upper plate includes a second protrusion (122) protruded toward the first upper plate. The first and second upper plates are combined to each other using the combination of the first and second protrusions.
Abstract translation: 目的：提供生物传感器以快速分离样品中的分析物体，并防止样品泄漏。 构成：生物传感器（10）包括：下板（200），包括检测单元; 包括彼此面对的第一上板（110）和第二上板（120）的上板（100），并与下板组合; 以及位于下板和上板之间的过滤器。 第一上板包括形成在与过滤器相对应的位置处的试样插入单元（114）和朝向第二上板突出的第一突起（112）。 第二上板包括朝向第一上板突出的第二突起（122）。 使用第一和第二突起的组合将第一和第二上板彼此组合。
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