公开(公告)号：KR1020110120153A

公开(公告)日：2011-11-03

申请号：KR1020100039699

申请日：2010-04-28

Applicant: 고려대학교 산학협력단

Inventor： 이성준 ,  조보람 ,  박효민

IPC: A61K31/015 ,  A61K36/752 ,  A61P25/20 ,  A61P11/00

Abstract: PURPOSE: An adenosine A2a receptor agonist containing limonene is provided to ensure sleep promotion and anti-inflammation. CONSTITUTION: An adenosine A2a receptor agonist contains limonene as an active ingredient. The limoenen is isolated from citrus rind. A pharmaceutical composition for sleep promotion contains the adenosine A2a receptor agonist. A pharmaceutical composition for anti-inflammation contains the adenosine A2a receptor agonist. The pharmaceutical composition is used in the form of powder, granules, tablets, emulsion, syrup, aerosol, or soft or hard gelatin capsule. The dose of the pharmaceutical composition is 0.01-1000 mg/kg for adult.

Abstract translation: 目的：提供含有柠檬烯的腺苷A2a受体激动剂，以确保睡眠促进和抗炎。 构成：腺苷A2a受体激动剂含有柠檬烯作为活性成分。 柠檬油是从柑橘皮中分离出来的。 用于睡眠促进的药物组合物含有腺苷A2a受体激动剂。 用于抗炎的药物组合物含有腺苷A2a受体激动剂。 药物组合物以粉末，颗粒，片剂，乳剂，糖浆，气溶胶或软或硬明胶胶囊的形式使用。 成人剂量为0.01-1000mg / kg。