웨스턴 블럿팅 및 면역침강에 이용 가능한 셀레노프로테인 S의 항체 및 그 제조방법
    2.
    发明公开
    웨스턴 블럿팅 및 면역침강에 이용 가능한 셀레노프로테인 S의 항체 및 그 제조방법 有权
    抗西班牙白蛋白抗体可用于西班牙和免疫反应及其制备方法

    公开(公告)号:KR1020100077399A

    公开(公告)日:2010-07-08

    申请号:KR1020080135322

    申请日:2008-12-29

    Abstract: PURPOSE: A selenoprotein S antibody and a method for manufacturing the same are provided to use in western blotting and immunoprecipitation. CONSTITUTION: An antibody which specifically binds to selenoprotein S comprises an amino acid sequence of sequence number 1 or 2. A method for manufacturing the antibody comprises: a step of injecting a peptide of sequence number 1 or 2; and a step of collecting antibody which specifically binds to selenoprotein S from an animal. The peptide contains cystein at N-terminal and is aminated at C-terminal. A gene encoding mutated selenoprotein S comprises TGC sequence which is substituted from TGA, selenocystein codon of selenoprotein S. A kit for diagnosing diabetes or inflammatory diseases contains the selenoprotein S antibody.

    Abstract translation: 目的:提供硒蛋白S抗体及其制备方法用于蛋白质印迹和免疫沉淀。 构成:特异性结合硒蛋白S的抗体包含序列号1或2的氨基酸序列。制备抗体的方法包括:注射序列号1或2的肽的步骤; 以及从动物中收集与硒蛋白S特异性结合的抗体的步骤。 肽含有N-末端的半胱氨酸,并在C末端进行胺化。 编码突变的硒蛋白S的基因包括由TGA,硒蛋白S的硒半胱氨酸密码子取代的TGC序列。用于诊断糖尿病或炎性疾病的试剂盒含有硒蛋白S抗体。

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