公开(公告)号：KR101259688B1

公开(公告)日：2013-05-02

申请号：KR1020100138318

申请日：2010-12-29

Applicant: 고려대학교 산학협력단

Inventor： 송문정 ,  한진아 ,  이동호

IPC: A61K31/37 ,  A61K31/366 ,  A61P31/12

Abstract: 본발명은안젤리신(angelicin) 또는그의약학적으로허용가능한염을유효성분으로함유하는항허피스바이러스용약학적조성물을제공한다. 상술한본 발명에의하면감마허피스바이러스등 허피스바이러스에의한질환내지질병을약물독성또는약물내성없이효율적으로치료또는예방할수 있는이점이있다.

公开(公告)号：KR1020120076247A

公开(公告)日：2012-07-09

申请号：KR1020100138318

申请日：2010-12-29

Applicant: 고려대학교 산학협력단

Inventor： 송문정 ,  한진아 ,  이동호

IPC: A61K31/37 ,  A61K31/366 ,  A61P31/12

Abstract: PURPOSE: A pharmaceutical composition containing angelicin or phramaceutically accepable salt thereof is provided to effectively treat or prevent diseases by herpes virus without drug toxicity or drug resistance. CONSTITUTION: A pharmaceutical composition for anti-herpes contains angelicin of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. The angelicin is derived from Psoralea corylifolia. The composition has an antiviral activity to gamma herpes virus including Epstein-Barr virus(EBV) or Kaposi's sarcoma associated virus(KSHV). The concentration of the angelicin is 15-120 ug/ml.

Abstract translation: 目的：提供含有安琪霉素或其药物可接受的盐的药物组合物，以有效治疗或预防疱疹病毒的疾病，无药物毒性或耐药性。 构成：抗疱疹药物组合物含有化学式1的安息香素或其药学上可接受的盐作为活性成分。 天竺葵素来自茯苓（Psoralea corylifolia）。 该组合物对包括爱泼斯坦 - 巴尔病毒（EBV）或卡波西肉瘤相关病毒（KSHV）的γ疱疹病毒具有抗病毒活性。 天angel素的浓度为15-120ug / ml。