公开(公告)号：KR1020140110565A

公开(公告)日：2014-09-17

申请号：KR1020130025144

申请日：2013-03-08

Applicant: 대구한의대학교산학협력단

Inventor： 이진태 ,  전동하 ,  권대준 ,  김희영 ,  김학윤 ,  장영아 ,  김세현

IPC: A61K36/49 ,  A61P17/00

CPC classification number: A61K36/49 ,  A61K8/02 ,  A61K8/97 ,  A61K9/06 ,  A61K9/70 ,  A61Q17/04 ,  A61Q19/00

Abstract: The present invention relates to a composition comprising a chestnut shell extract or a purified extract thereof as an active ingredient and, more specifically, to the composition that can be usefully applied as a pharmaceutical composition or a cosmetic composition for external skin application for preventing and treating skin aging by confirming that the chestnut shell extract or the purified extract thereof is excellent in DPPH radical scavenging activity, increasing ABTS radical cation decolorization activity, increasing superoxide dismutase (SOD) like activity, measuring inhibitory activity of xanthine oxidase, and nitrite scavenging inhibitory activity.

Abstract translation: 本发明涉及包含栗子壳提取物或其纯化提取物作为活性成分的组合物，更具体地说，涉及可用作药物组合物或外用皮肤防治用化妆品组合物的组合物 通过证实栗子壳提取物或其纯化提取物具有优异的DPPH自由基清除活性，增加ABTS自由基阳离子脱色活性，增加超氧化物歧化酶（SOD）活性，测量黄嘌呤氧化酶的抑制活性和亚硝酸盐清除抑制活性 。