Abstract:
본 발명은 이카리틴 및 퀘르세틴을 포함하는 간질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명은 이카리틴 및 퀘르세틴을 보함하는 간질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 조성물은 이카리틴 또는 퀘르세틴 단독 사용에 비해 혼합 사용할 경우 간세포보호효과가 우수한 것을 확인하고, 최적배합비를 도출하였으며, 또한 상기 조성물은 간보호작용을 보이며 정상 세포에 독성을 유발하지 않는다는 것을 확인함으로써, 간질환 치료제 또는 간질환 예방을 위한 건강기능성 식품의 유효성분으로 사용할 수 있는 효과가 있다.
Abstract:
A food additive composition containing a mixed herb medicine extract of licorice root, wheat, and jujube is provided to be used as a food additive by confirming an excellent cerebral nerve protecting activity which shows the shortening of escape latency through the water-maze performance in animal models having cerebral nerve damage derived by beta amyloid. A food additive composition containing a mixed herb medicine extract of licorice root, wheat, and jujube is prepared by mixing licorice root, wheat, and jujube in a dried weight ratio of 1~10:5~50:1~10; settling the herb mixture in distilled water as a solvent at 30~100°C for 0.5~10hr, wherein the volume ratio of the herb mixture and the distilled water is 1:1~30; hydrothermal-extracting it; centrifuging, filtering, and concentrating the extract, wherein the 0.01~90wt% of the extract is included in 100wt% of the composition. In addition, other herb medicine is able to be selected from the group consisting of Euphoria longana, Bambusae Caulis in Liquamen, Astragali radix, Zizyphi spinosi Semen, Amomum villosum Lour, radish, ginseng, pine needles, red ginseng, Alpinia oxyphylla miquel, Polygala tenuifolia Willdenow, or iris. The extracting solvent is one or more solvents selected from the group consisting of water comprising refined water, C1-C4 lower alcohol, or propylene glycol, ethyl acetate, butylene glycol, ether, and chloroform.
Abstract:
A composition for treating and preventing obesity comprising the extract of Zizyphus jujuba Mill. var. inermis Rehder is provided to inhibit body weight increase, reduce neutral lipid concentration and cholesterol concentration, and increase high density cholesterol concentration. The composition for treating and preventing obesity comprises the extract of Zizyphus jujuba Mill. var. inermis Rehder as an effective ingredient, wherein the Zizyphus jujuba Mill. var. inermis Rehder extract is prepared with a solvent selected from water, ethanol and methanol; the amount of the Zizyphus jujuba Mill. var. inermis Rehder extract is 0.1-50 wt.%; the daily dosage of Zizyphus jujuba Mill. var. inermis Rehder extract is 0.0001 to 100 mg/kg; and the composition is a health food composition.